Results 61 to 70 of about 182,211 (308)

Ovarian cancer ascites increase Mcl-1 expression in tumor cells through ERK1/2-Elk-1 signaling to attenuate TRAIL-induced apoptosis

open access: yesMolecular Cancer, 2012
Background Ascites may affect the progression of ovarian cancer (OC). In particular, soluble factors present in OC ascites can create a protective environment for tumor cells that promote de novo resistance to drug- and death receptor-induced apoptosis ...
Goncharenko-Khaider Nadzeya   +4 more
doaj   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

open access: yesAdvanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng   +16 more
wiley   +1 more source

A Male Infant with Congenital Chylous Ascites Accompanied by Hypertension

open access: yesErciyes Medical Journal, 2020
Background: Congenital chylous ascites is a condition that arises from a disorder of the abdominal lymphatic system. Case Report: In this case study, a nine-month-old infant diagnosed with congenital chylous ascites in the newborn period presented with ...
Derya Altay   +3 more
doaj   +1 more source

Prognostic value of the ascites characteristics in pseudomyxoma peritonei originating from the appendix

open access: yesFrontiers in Surgery, 2023
BackgroundPseudomyxoma peritonei (PMP) is a rare disease, with the overall survival (OS) influenced by many factors. To date, no ascites characteristics have been reported to predict OS of patients with PMP.
Bing Wang   +16 more
doaj   +1 more source

Differential Diagnosis of Gynecologic Organ-Related Diseases in Women Presenting with Ascites

open access: yes, 2010
Ascites is a pathologic accumulation of fluid within the peritoneal cavity, and usually develops as a result of liver disease, congestive heart failure or nephrotic syndrome. Ascites is also a common manifestation of some gynecologic diseases.
鄭敏慧;顏明賢;趙灌中;許博欽;王鵬惠   +1 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Chronic recurrent biliary ascites: An unusual scenario [PDF]

open access: yesScripta Medica, 2014
Biliary ascites in adults occurs most often as a complication of biliary procedures - endoscopic, radiologic or operative, but can occur after trauma as well.
Kutty Geeta, Gupta Shweta, Sekosan Marin
doaj  

Efficacy and Safety of Ascites Treatment in Liver Cirrhosis

open access: yesБезопасность и риск фармакотерапии, 2022
Cirrhosis is one of the major health problems worldwide; and ascites is often its first and foremost manifestation. Despite the advances in modern hepatology, the presence of ascites is associated with a poor prognosis and high mortality.
G. A. Ignatenko   +4 more
doaj   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

open access: yesAdvanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu   +7 more
wiley   +1 more source

Delayed Presentation of Bladder Rupture Presenting as Ascites and Acute Kidney Injury

open access: yes, 2023
We report the case of a middle-aged male who presented with an acute abdomen with imaging findings suspicious for ascites and bloods suggestive of an acute kidney injury.
Nicol, Alice   +2 more
core   +1 more source

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