Results 1 to 10 of about 1,215,632 (331)

Cellular and Humoral Immune Responses after Immunisation with Low Virulent African Swine Fever Virus in the Large White Inbred Babraham Line and Outbred Domestic Pigs

Viruses, 2022
African swine fever virus is currently present in all of the world’s continents apart from Antarctica, and efforts to control the disease are hampered by the lack of a commercially available vaccine.
Lynnette C. Goatley, Rachel H. Nash, Catherine Andrews, Zoe Hargreaves, Priscilla Tng, Ana Luisa Reis, Simon P. Graham, Christopher L. Netherton   +7 more
doaj   +1 more source

Development and Validation of a Mucosal Antibody (IgA) Test to Identify Persistent Infection with Foot-and-Mouth Disease Virus

Viruses, 2021
It is well known that approximately 50% of cattle infected with foot-and-mouth disease (FMD) virus (FMDV) may become asymptomatic carrier (persistently infected) animals.
Jitendra K. Biswal, Antonello Di Nardo, Geraldine Taylor, David J. Paton, Satya Parida   +4 more
doaj   +1 more source

Molecular Basis of Antigenic Drift in Serotype O Foot-and-Mouth Disease Viruses (2013–2018) from Southeast Asia

Viruses, 2021
Foot and mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals with serious economic consequences. FMD is endemic in Southeast Asia (SEA) and East Asia (EA) with the circulation of multiple serotypes, posing a threat to Australia ...
Sasmita Upadhyaya, Mana Mahapatra, Valerie Mioulet, Satya Parida   +3 more
doaj   +1 more source

The Identification of Host Proteins That Interact with Non-Structural Proteins-1α and -1β of Porcine Reproductive and Respiratory Syndrome Virus-1

Viruses, 2023
Porcine reproductive and respiratory syndrome viruses (PRRSV-1 and -2) are the causative agents of one of the most important infectious diseases affecting the global pig industry.
Sofia Riccio, Kay Childs, Ben Jackson, Simon P. Graham, Julian Seago   +4 more
doaj   +1 more source

Capsid-Specific Antibody Responses of Domestic Pigs Immunized with Low-Virulent African Swine Fever Virus

Vaccines, 2023
African swine fever (ASF) is a lethal disease in pigs that has grave socio-economic implications worldwide. For the development of vaccines against the African swine fever virus (ASFV), immunogenic antigens that generate protective immune responses need ...
Priscilla Y. L. Tng, Laila Al-Adwani, Egle Pauletto, Joshua Y. K. Hui, Christopher L. Netherton   +4 more
doaj   +1 more source

Identification of a BTV-Strain-Specific Single Gene That Increases Culicoides Vector Infection Rate

Viruses, 2021
Since the 2000s, the distribution of bluetongue virus (BTV) has changed, leading to numerous epidemics and economic losses in Europe. Previously, we found a BTV-4 field strain with a higher infection rate of a Culicoides vector than a BTV-1 field strain ...
Honorata M. Ropiak, Simon King, Marc Guimerà Busquets, Kerry Newbrook, Gillian D. Pullinger, Hannah Brown, John Flannery, Simon Gubbins, Carrie Batten, Paulina Rajko-Nenow, Karin E. Darpel   +10 more
doaj   +1 more source

A Pool of Eight Virally Vectored African Swine Fever Antigens Protect Pigs against Fatal Disease

Vaccines, 2020
Classical approaches to African swine fever virus (ASFV) vaccine development have not been successful; inactivated virus does not provide protection and use of live attenuated viruses generated by passage in tissue culture had a poor safety profile ...
Lynnette C. Goatley, Ana Luisa Reis, Raquel Portugal, Hannah Goldswain, Gareth L. Shimmon, Zoe Hargreaves, Chak-Sum Ho, María Montoya, Pedro J. Sánchez-Cordón, Geraldine Taylor, Linda K. Dixon, Christopher L. Netherton   +11 more
doaj   +1 more source

An Improved αvβ6-Receptor-Expressing Suspension Cell Line for Foot-and-Mouth Disease Vaccine Production

Viruses, 2022
Foot-and-mouth disease (FMD) is endemic in large parts of sub-Saharan Africa, Asia and South America, where outbreaks in cloven-hooved livestock threaten food security and have severe economic impacts.
Yongjie Harvey, Ben Jackson, Brigid Veronica Carr, Kay Childs, Katy Moffat, Graham Freimanis, Chandana Tennakoon, Nicholas Juleff, Julian Seago   +8 more
doaj   +1 more source

Demonstration of Co-Infection and Trans-Encapsidation of Viral RNA In Vitro Using Epitope-Tagged Foot-and-Mouth Disease Viruses

Viruses, 2021
Foot-and-mouth disease, caused by foot-and-mouth disease virus (FMDV), is an economically devastating disease affecting several important livestock species.
Kay Childs, Nicholas Juleff, Katy Moffat, Julian Seago   +3 more
doaj   +1 more source

Maternally Derived Antibodies to Foot-and-Mouth Disease Virus Modulate the Antigenic Specificity of Humoral Responses in Vaccinated Cattle

Vaccines, 2023
Vaccination is widely used to control foot-and-mouth disease (FMD), but maternal antibodies may interfere with the response to vaccination in calves. This study, conducted on a regularly vaccinated Malaysian dairy farm, aimed to optimise the vaccination ...
Jamaliah Senawi, Ginette Wilsden, Clare F. J. Browning, Anna B. Ludi, Mazatonazuar Meor Ismail, Halimah Senin, Simon Gubbins, Donald P. King, David J. Paton   +8 more
doaj   +1 more source