Results 1 to 10 of about 10,541 (227)

Preparation and Characterization of Nanoliposome Containing Isolated VP1 Protein of Foot and Mouth Disease Virus as a Model of Vaccine [PDF]

open access: yesArchives of Razi Institute, 2022
Foot-and-mouth disease (FMD) is an acute and highly contagious disease in livestock, such as cattle, sheep, and pigs, leading to a lot of economic losses.
M Kazemi   +5 more
doaj   +1 more source

An anti-picornaviral strategy based on the crystal structure of foot-and-mouth disease virus 2C protein

open access: yesCell Reports, 2022
Summary: The foot-and-mouth disease virus (FMDV) 2C protein shares conserved motifs with enterovirus 2Cs despite low sequence identity. Here, we determine the crystal structure of an FMDV 2C fragment to 1.83 Å resolution, which comprises an ATPase domain,
Chu Zhang   +10 more
doaj   +1 more source

Analysis of Foot and Mouth Disease Virus Polyprotein for Multi Peptides Vaccine Design: An In silico Strategy

open access: yesJournal of Pure and Applied Microbiology, 2022
Foot-and-mouth disease virus (FMDV) is small RNA virus from Picornaviridae family; genus Aphthovirus. FMDV causes maximum levels of infectivity in cattle and harmful socioeconomic effects. The present report attempted to design vaccine candidate from the
Ranya Mohmed Sid Ahmed   +2 more
doaj   +1 more source

A Single Dose of Dendrimer B2T Peptide Vaccine Partially Protects Pigs against Foot-and-Mouth Disease Virus Infection

open access: yesVaccines, 2020
Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed animals whose control relies on efficient vaccination. We have reported that dendrimer peptide B2T, with two copies of FMDV B-cell epitope VP1 (136−154) linked ...
Rodrigo Cañas-Arranz   +8 more
doaj   +1 more source

High-Resolution Composition Analysis of an Inactivated Polyvalent Foot-and-Mouth Disease Vaccine

open access: yesPathogens, 2020
Appropriate vaccine selection is crucial in the control of foot-and-mouth disease (FMD). Vaccination can prevent clinical disease and reduces viral shedding, but there is a lack of cross-protection between the seven serotypes and their sublineages ...
Leonie F. Forth   +3 more
doaj   +1 more source

Into the Deep (Sequence) of the Foot-and-Mouth Disease Virus Gene Pool: Bottlenecks and Adaptation during Infection in Naïve and Vaccinated Cattle

open access: yesPathogens, 2020
Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been described in detail in natural host species. In this study, virus samples collected
Ian Fish   +4 more
doaj   +1 more source

Molecular and serological typing of foot-and-mouth disease virus serotypes currently circulating in Egypt [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2021
Foot-and-mouth disease (FMD) is an extremely contagious viral disease affects all cloven- hoofed animals. The present study aimed to investigate the epidemiological situation of FMD in Egypt during 2017 and 2018, based on antigenic and genetic ...
Maryam M. ِbd El-Rhman   +3 more
doaj   +1 more source

Transient Expression of Coat Protein of Foot and Mouth Disease Virus (FMDV) in Alfalfa (Medicago sativa) by Agroinfiltration [PDF]

open access: yesJournal of Cell and Molecular Research, 2016
An Agrobacterium-mediated transient gene expression assay was carried out in alfalfa (Medicago sativa) leaves for expression of a chimeric gene encoding a part of capsid protein of Foot and Mouth Disease virus called VP1.
Maziar Habibi-Pirkoohi   +5 more
doaj   +1 more source

Antiviral Activity Of Adamantane-Pyrazole Derivatives Against Foot And Mouth Disease Virus Infection In Vivo And In Vitro With Molecular Docking Study

open access: yesJournal of Applied Veterinary Sciences, 2020
Foot-and-mouth disease (FMD) vaccine does not afford early effective protection until adaptive immune protection caused by the vaccination occurs. Therefore, an alternative prophylactic application of antiviral agents for inhibition of the FMD virus is ...
Mohammed M. S. Wassel   +4 more
doaj   +1 more source

A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid Particles. [PDF]

open access: yesPLoS ONE, 2016
Foot-and-mouth disease (FMD) remains one of the most economically important infectious diseases of production animals globally. Vaccination can successfully control this disease, however, current vaccines are imperfect.
Maria Gullberg   +7 more
doaj   +1 more source

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