Results 1 to 10 of about 11,472 (171)

Development of a Competitive Chemiluminescent Enzyme Immunoassay Based on Recombinant FMDV VP2 Protein for Rapid and Simultaneous Detection of Antibodies Against Foot-and-Mouth Disease Virus Serotypes O and A [PDF]

open access: yesVeterinary Sciences
Timely detection of specific antibodies against foot-and-mouth disease virus (FMDV) is critical to effective prevention and control of the disease.
Shi’ao Bian   +7 more
doaj   +2 more sources

Preparation and Characterization of Nanoliposome Containing Isolated VP1 Protein of Foot and Mouth Disease Virus as a Model of Vaccine [PDF]

open access: yesArchives of Razi Institute, 2022
Foot-and-mouth disease (FMD) is an acute and highly contagious disease in livestock, such as cattle, sheep, and pigs, leading to a lot of economic losses.
M Kazemi   +5 more
doaj   +1 more source

An anti-picornaviral strategy based on the crystal structure of foot-and-mouth disease virus 2C protein

open access: yesCell Reports, 2022
Summary: The foot-and-mouth disease virus (FMDV) 2C protein shares conserved motifs with enterovirus 2Cs despite low sequence identity. Here, we determine the crystal structure of an FMDV 2C fragment to 1.83 Å resolution, which comprises an ATPase domain,
Chu Zhang   +10 more
doaj   +1 more source

Analysis of Foot and Mouth Disease Virus Polyprotein for Multi Peptides Vaccine Design: An In silico Strategy

open access: yesJournal of Pure and Applied Microbiology, 2022
Foot-and-mouth disease virus (FMDV) is small RNA virus from Picornaviridae family; genus Aphthovirus. FMDV causes maximum levels of infectivity in cattle and harmful socioeconomic effects. The present report attempted to design vaccine candidate from the
Ranya Mohmed Sid Ahmed   +2 more
doaj   +1 more source

Leaderless FMDV is fully attenuated in vivo and unable to establish persistent infection

open access: yes, 2023
International audienceMany ways of attenuation of foot-and-mouth disease virus (FMDV) have been ex-plored. One successful method is the deletion of most of the coding sequence for the Leader proteinase Lpro.
Pfaff, Florian   +7 more
core   +3 more sources

A Single Dose of Dendrimer B2T Peptide Vaccine Partially Protects Pigs against Foot-and-Mouth Disease Virus Infection

open access: yesVaccines, 2020
Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed animals whose control relies on efficient vaccination. We have reported that dendrimer peptide B2T, with two copies of FMDV B-cell epitope VP1 (136−154) linked ...
Rodrigo Cañas-Arranz   +8 more
doaj   +1 more source

High-Resolution Composition Analysis of an Inactivated Polyvalent Foot-and-Mouth Disease Vaccine

open access: yesPathogens, 2020
Appropriate vaccine selection is crucial in the control of foot-and-mouth disease (FMD). Vaccination can prevent clinical disease and reduces viral shedding, but there is a lack of cross-protection between the seven serotypes and their sublineages ...
Leonie F. Forth   +3 more
doaj   +1 more source

Into the Deep (Sequence) of the Foot-and-Mouth Disease Virus Gene Pool: Bottlenecks and Adaptation during Infection in Naïve and Vaccinated Cattle

open access: yesPathogens, 2020
Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been described in detail in natural host species. In this study, virus samples collected
Ian Fish   +4 more
doaj   +1 more source

Molecular and serological typing of foot-and-mouth disease virus serotypes currently circulating in Egypt [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2021
Foot-and-mouth disease (FMD) is an extremely contagious viral disease affects all cloven- hoofed animals. The present study aimed to investigate the epidemiological situation of FMD in Egypt during 2017 and 2018, based on antigenic and genetic ...
Maryam M. ِbd El-Rhman   +3 more
doaj   +1 more source

Transient Expression of Coat Protein of Foot and Mouth Disease Virus (FMDV) in Alfalfa (Medicago sativa) by Agroinfiltration [PDF]

open access: yesJournal of Cell and Molecular Research, 2016
An Agrobacterium-mediated transient gene expression assay was carried out in alfalfa (Medicago sativa) leaves for expression of a chimeric gene encoding a part of capsid protein of Foot and Mouth Disease virus called VP1.
Maziar Habibi-Pirkoohi   +5 more
doaj   +1 more source

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