Results 11 to 20 of about 14,055 (218)

Protein coexpression using FMDV 2A : effect of “linker” residues [PDF]

BioMed Research International, 2013
This article was made open access through BIS OA funding. The research was supported by the MRC.Many biomedical applications absolutely require, or are substantially enhanced by, coexpression of multiple proteins from a single vector.
Minskaia, Ekaterina, Ryan, Martin D.
core   +7 more sources

Immunohistochemical Detection of Foot-and-Mouth Disease Virus in Carrier African Buffalo (Syncerus caffer). [PDF]

Vet Med Sci
FMD viral antigen was consistently associated with the vasculature of the coronary band and interdigital skin as well as in the lungs. The IHC results revealed a novel association of viral antigen with vascular tissue and demonstrated the potential for superior sensitivity over PCR. ABSTRACT Background African buffalo are long‐term carriers of foot‐and‐
Henning A, Quan M, Loots A, Odendaal L.
europepmc   +2 more sources

Molecular Evolution and Epidemiological Dynamics of Foot-and-Mouth Disease Virus O/ME-SA/Ind-2001e Circulating in East Java, Indonesia, in 2022-2025. [PDF]

Vet Med Int
Background Indonesia has been free from foot‐and‐mouth disease virus (FMDV) for decades, but in April 2022, the first major re‐emerging of FMDV was detected in Gresik, East Java, and later spreading nationwide. To understand how dynamic virus spread occurs in Indonesia, we performed an epidemiological study and molecular evolution analyses.
Dinana Z, Rahmahani J, Suwarno, Hamid IS, Al-Arif MA, Yunus M, Tyasningsih W, Ihsan IS, Maharani AT, Maulana FK, Said NS, Fahrodi DU, Rantam FA.   +12 more
europepmc   +2 more sources

FMDV 3A cooperates with PDCD10 to promote FMDV replication by inhibiting VISA-mediated innate immunity. [PDF]

J Virol
ABSTRACT RIG-I like receptors (RLRs) recognize RNA viruses and induce an innate immune response. Although many host factors strictly regulate the signal transduction of the RLR pathway, the mechanisms remain unclear. In the present study, we demonstrated that virus infection slightly increased
Li Q, Nian X, Shang X, Zeng Z, Luo Z, Du B, Ma M, Zhu Z, Yang F, Pei J, Cao W, Yan H, Li L, Xu Y, Ma X, Zheng H.   +15 more
europepmc   +2 more sources

Recovery of viral RNA and infectious foot-and-mouth disease virus from positive lateral-flow devices [PDF]

, 2014
Foot-and-mouth disease Virus (FMDV) is an economically important, highly contagious picornavirus that affects both wild and domesticated cloven hooved animals. In developing countries, the effective laboratory diagnosis of foot-and-mouth disease (FMD) is
Armson, Bryony, Bankowski, Bartlomiej M., Barnett, Paul V., Di Nardo, Antonello, Ferris, Nigel P., Fowler, Veronica L., King, Donald P., Mioulet, Valerie, Reid, Scott M., Valdazo-Gonzalez, Begoña, Wadsworth, Jemma   +10 more
core   +10 more sources

Transient Expression of Coat Protein of Foot and Mouth Disease Virus (FMDV) in Alfalfa (Medicago sativa) by Agroinfiltration [PDF]

Journal of Cell and Molecular Research, 2016
An Agrobacterium-mediated transient gene expression assay was carried out in alfalfa (Medicago sativa) leaves for expression of a chimeric gene encoding a part of capsid protein of Foot and Mouth Disease virus called VP1.
Maziar Habibi-Pirkoohi, Saeid Malekzadeh-Shafaroudi, Hasan Marashi, Saeid Zibaee, Afsaneh Mohkami, Saba NejatizaXeh   +5 more
doaj   +1 more source

Antiviral Activity Of Adamantane-Pyrazole Derivatives Against Foot And Mouth Disease Virus Infection In Vivo And In Vitro With Molecular Docking Study

Journal of Applied Veterinary Sciences, 2020
Foot-and-mouth disease (FMD) vaccine does not afford early effective protection until adaptive immune protection caused by the vaccination occurs. Therefore, an alternative prophylactic application of antiviral agents for inhibition of the FMD virus is ...
Mohammed M. S. Wassel, Wael M. Gamal El-Din , Ahmed Ragab, Gameel A. M. Elhag Ali, Yousry A. Ammar   +4 more
doaj   +1 more source

Picornavirus infection enhances aspartate by the SLC38A8 transporter to promote viral replication.

PLoS Pathogens, 2023
Foot-and-mouth disease, a class of animal diseases, is caused by foot-and-mouth disease virus (FMDV). The metabolic changes during FMDV infection remain unclear. Here, PK-15 cells, serum, and tonsils infected with FMDV were analyzed by metabolomics.
Huisheng Liu, Zixiang Zhu, Qiao Xue, Fan Yang, Weijun Cao, Zhaoning Xue, Xiangtao Liu, Haixue Zheng   +7 more
doaj   +1 more source

Foot-and-mouth disease virus localisation on follicular dendritic cells and sustained induction of neutralising antibodies is dependent on binding to complement receptors (CR2/CR1).

PLoS Pathogens, 2022
Previous studies have shown after the resolution of acute infection and viraemia, foot-and-mouth disease virus (FMDV) capsid proteins and/or genome are localised in the light zone of germinal centres of lymphoid tissue in cattle and African buffalo.
Lucy Gordon, Neil Mabbott, Joanna Wells, Liudmila Kulik, Nick Juleff, Bryan Charleston, Eva Perez-Martin   +6 more
doaj   +1 more source

Heterogeneity and Recombination of Foot-and-Mouth Disease Virus during Multi-Strain Coinfection of Cattle

mSphere, 2023
Superinfection of cattle persistently infected with foot-and-mouth disease virus (FMDV), with a heterologous FMDV strain has been shown to generate novel recombinant viruses.
Carolina Stenfeldt, Ian Fish, Haillie C. Meek, Jonathan Arzt   +3 more
doaj   +1 more source