Results 41 to 50 of about 7,295 (180)

Virus-like particles of recombinant PCV2b carrying FMDV-VP1 epitopes induce both anti-PCV and anti-FMDV antibody responses [PDF]

Applied Microbiology and Biotechnology, 2018
Mixed infection of porcine circovirus type 2 (PCV2) and foot-and-mouth disease virus (FMDV) is devastating to swine populations. To develop an effective vaccine that can protect the pigs from the infection of PCV2 and FMDV, we used the neutralizing B cell epitope region (aa 135-160) of FMDV to replace the regions aa 123-151 and aa 169-194 of the PCV2b ...
Xin, Li, Xiuping, Meng, Shengnan, Wang, Zhiqin, Li, Lei, Yang, Liqun, Tu, Wenzhen, Diao, Cheng, Yu, Yongli, Yu, Chaoying, Yan, Liying, Wang   +10 more
openaire   +2 more sources

Functional advantages of triplication of the 3B coding region of the FMDV genome [PDF]

The FASEB Journal, 2020
Abstract For gene duplication to be maintained, particularly in the small genomes of RNA viruses, this should offer some advantages. We have investigated the functions of a small protein termed VPg or 3B, which acts as a primer in the replication of foot‐and‐mouth disease virus (FMDV).
Oluwapelumi O. Adeyemi, Joseph C. Ward, Joseph S. Snowden, Morgan R. Herod, David J. Rowlands, Nicola J. Stonehouse   +5 more
openaire   +4 more sources

FMDV Leader Protein Interacts with the NACHT and LRR Domains of NLRP3 to Promote IL-1β Production

Viruses, 2021
Foot-and-mouth disease virus (FMDV) infection causes inflammatory clinical symptoms, such as high fever and vesicular lesions, even death of animals.
Sk Mohiuddin Choudhury, Xusheng Ma, Yuanyuan Li, Xiaofeng Nian, Zhikuan Luo, Yonghua Ma, Zixiang Zhu, Fan Yang, Weijun Cao, Haixue Zheng   +9 more
doaj   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

Animal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng, Xuyan Xiang, Xinyu Qi, Hanrong Zhou, Peiyu Xiao, Fandan Meng, Tongqing An, Haiwei Wang   +7 more
wiley   +1 more source

FMDV 3A cooperates with PDCD10 to promote FMDV replication by inhibiting VISA-mediated innate immunity

Journal of Virology
ABSTRACT RIG-I like receptors (RLRs) recognize RNA viruses and induce an innate immune response. Although many host factors strictly regulate the signal transduction of the RLR pathway, the mechanisms remain unclear. In the present study, we demonstrated that virus infection slightly increased
Qian Li, XiaoFeng Nian, XiaoFen Shang, ZongBo Zeng, ZhiKuan Luo, Bo Du, MeiHua Ma, ZiXiang Zhu, Fan Yang, JingJing Pei, WeiJun Cao, HongBin Yan, Li Li, YiGang Xu, XuSheng Ma, HaiXue Zheng   +15 more
openaire   +3 more sources

A gold nanoparticle strip for simultaneously evaluating FMDV immunized antibody level and discriminating FMDV vaccinated animals from infected animals

RSC Advances, 2019
A gold nanoparticle strip was developed for rapidly evaluating FMDV type O antibody level and simultaneously discriminating FMDV vaccinated animals from infected animals.
Suzhen Yang, Yaning Sun, Jifei Yang, Yunchao Liu, Hua Feng, Gaiping Zhang   +5 more
openaire   +3 more sources

Location and Characterization of the Antigenic Portion of the FMDV Immunizing Protein

Journal of General Virology, 1982
Purified foot-and-mouth disease virus (FMDV) to type O1K was treated with several endopeptidases of differing specificity. The immunizing protein VPThr was cleaved into two detectable fragments by all enzymes except for glutamic acid-specific Staphylococcus aureus V8 protease.
K, Strohmaier, R, Franze, K H, Adam
openaire   +2 more sources

Foot-and-mouth disease virus O/ME-SA/Ind 2001 lineage outbreak in vaccinated Holstein Friesian cattle in Saudi Arabia in 2016

Veterinary Quarterly, 2018
Background: Foot-and-mouth disease virus (FMDV) is a highly contagious viral infection of large ruminants. Despite the massive application of vaccines against FMDV, several outbreaks are still being reported in Africa and Asia.
Maged Gomaa Hemida, Walid Rizk EL-Ghareeb, Fahad Al-Hizab, Abdelazim Ibrahim   +3 more
doaj   +1 more source

Early Growth Response Gene-1 Suppresses Foot-and-Mouth Disease Virus Replication by Enhancing Type I Interferon Pathway Signal Transduction

Frontiers in Microbiology, 2018
Early growth response gene-1 (EGR1) is a multifunctional transcription factor that is implicated in viral infection. In this study, we observed that foot-and-mouth disease virus (FMDV) infection significantly triggered EGR1 expression.
Zixiang Zhu, Xiaoli Du, Pengfei Li, Xiangle Zhang, Fan Yang, Weijun Cao, Hong Tian, Keshan Zhang, Xiangtao Liu, Haixue Zheng   +9 more
doaj   +1 more source

First Serological Evidence of Foot‐and‐Mouth Disease Virus (FMDV) Infection Among Sheep and Goats in Selected Districts of Central Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Serological surveillance revealed foot‐and‐mouth disease virus (FMDV) exposure for the first time in sheep and goats across the studied districts of Bangladesh, highlighting their critical role in FMD epidemiology. These findings emphasize the importance of including sheep and goats in national FMD surveillance and control programmes.
Tahmina Sikder, Md. Jisan Ahmed, Basant Saud, Tasmiah Tarin, Md. Imran Hossain, Anowar Hossen, Mohammed Abdus Samad, Mohammad Rafiqul Islam, Munazah Shahzad, Nadeem Shabir, Won‐Il Kim, Amina Khatun   +11 more
wiley   +1 more source