Results 41 to 50 of about 14,055 (218)

Viral Protein 1 (VP1) Sequence-Based Genetic Diversity of SAT 2 FMDV Circulating in Ethiopia from 1990 to 2015

Veterinary Medicine: Research and Reports, 2023
Fanos Woldemariyam,1,2 Jan Paeshuyse1 1Laboratory of Host-Pathogen Interaction, Division of Animal and Human Health Engineering, Department of Biosystems, KU Leuven, Leuven, Belgium; 2Department of Biomedical Sciences, College of Veterinary Medicine ...
Woldemariyam F, Paeshuyse J
doaj  

The Application of the Gibson Assembly Method in the Production of Two pKLS3 Vector-Derived Infectious Clones of Foot-and-Mouth Disease Virus

Vaccines, 2023
The construction of a full-length infectious clone, essential for molecular virological study and vaccine development, is quite a challenge for viruses with long genomes or possessing complex nucleotide sequence structures.
Ploypailin Semkum, Nattarat Thangthamniyom, Penpitcha Chankeeree, Challika Keawborisuth, Sirin Theerawatanasirikul, Porntippa Lekcharoensuk   +5 more
doaj   +1 more source

Crystal structure of the 3C protease from South African Territories type 2 foot-and-mouth disease virus [PDF]

, 2016
The replication of foot-and-mouth disease virus (FMDV) is dependent on the virus-encoded 3C protease (3Cpro). As in other picornaviruses, 3Cpro performs most of the proteolytic processing of the polyprotein expressed from the single open reading frame in
Curry, S, Leen, EN, Maree, FF, Yang, J
core   +4 more sources

FMDV RNA packaging and capsid assembly

, 2021
Foot-and-mouth disease virus (FMDV), of the Picornaviridae family, is a non-enveloped, single-stranded, positive-sense RNA virus. FMDV infects cloven-hooved animals and is an important pathogen for global agriculture due to the economic consequences of both endemic disease and epidemic outbreaks.
openaire   +2 more sources

Foot-and-Mouth Disease Virus 3C Protease Antagonizes Interferon Signaling and C142T Substitution Attenuates the FMD Virus

Frontiers in Microbiology, 2021
3C protease (3Cpro), a chymotrypsin-like cysteine protease encoded by the foot-and-mouth disease virus (FMDV), plays an essential role in processing the FMDV P1 polyprotein into individual viral capsid proteins in FMDV replication.
Pathum Ekanayaka, Sung Ho Shin, Prasanna Weeratunga, Hyuncheol Lee, Hyuncheol Lee, Tae-Hwan Kim, Tae-Hwan Kim, Kiramage Chathuranga, Ashan Subasinghe, Jong-Hyeon Park, Jong-Soo Lee   +10 more
doaj   +1 more source

A qualitative risk assessment of factors contributing to foot and mouth disease outbreaks in cattle along the western boundary of the Kruger National Park [PDF]

, 2009
Between November 2000 and the end of 2007, five outbreaks of foot and mouth disease (FMD) occurred in cattle in the area adjacent to the Kruger National Park (KNP) in the north-eastern corner of South Africa.
Bengis, R.G., Brahmbhatt, Dipa P., Du Plessis, B., Gummow, Bruce, Jori, Ferran, Thomson, G.R., Vosloo, Wilna   +6 more
core   +1 more source

Single-domain antibodies and their formatting to combat viral infections [PDF]

, 2018
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies, De Vlieger, Dorien, Rossey, Iebe, Saelens, Xavier, Schepens, Bert   +4 more
core   +2 more sources

A gold nanoparticle strip for simultaneously evaluating FMDV immunized antibody level and discriminating FMDV vaccinated animals from infected animals

RSC Advances, 2019
A gold nanoparticle strip was developed for rapidly evaluating FMDV type O antibody level and simultaneously discriminating FMDV vaccinated animals from infected animals.
Suzhen Yang, Yaning Sun, Jifei Yang, Yunchao Liu, Hua Feng, Gaiping Zhang   +5 more
openaire   +3 more sources

Sensitivity of specimen type for diagnosing foot-and-mouth diseases in cattle using one-step real-time polymerase chain reaction (3D gene)

Open Veterinary Journal
Background: Indonesia is currently experiencing a foot and mouth disease (FMD) outbreak in livestock, caused by the foot and mouth disease virus. FMDV is easily spread to cause outbreaks in new geographical locations. Identifying Foot and mouth diseases
Siswani Siswani, Mochammad Hatta, Muflihanah Muflihanah, Nurul Muslinah Muhiddin, Fitrine Ekawasti, Rini Damayanti, Riza Zainuddin Ahmad, Putri Reno Intan, Fitriana Fitriana, Muhammad Ibrahim Desem, Ratih Rinendyaputri   +10 more
doaj   +1 more source

Immunomodulatory effect of Isoprinosine on sheep immune response to FMDV [PDF]

Journal of Applied Veterinary Sciences
The present study evaluated the immunomodulatory effect of Isoprinosine when incorporated into an oil adjuvanted polyvalent foot and mouth disease (FMD) vaccine and administered to sheep. The investigation was conducted in two phases.
Ehab Ibrahim, Heba Attia, Mohamed Gamil, Safy Mahdy   +3 more
doaj   +1 more source