Results 61 to 70 of about 7,295 (180)

Immunomodulatory effect of Isoprinosine on sheep immune response to FMDV [PDF]

Journal of Applied Veterinary Sciences
The present study evaluated the immunomodulatory effect of Isoprinosine when incorporated into an oil adjuvanted polyvalent foot and mouth disease (FMD) vaccine and administered to sheep. The investigation was conducted in two phases.
Ehab Ibrahim, Heba Attia, Mohamed Gamil, Safy Mahdy   +3 more
doaj   +1 more source

Foot-and-mouth disease virus VP1 promotes viral replication by regulating the expression of chemokines and GBP1

Frontiers in Veterinary Science, 2022
Foot-and-mouth disease virus (FMDV) is an acute, highly contagious, and economically destructive pathogen of vesicular disease that affects domestic and wild cloven-hoofed animals. The FMDV VP1 protein is an important part of the nucleocapsid and plays a
Li Yang, Li Yang, Li Yang, Hong Chen, Hong Chen, Hong Chen, Liqing Liu, Liqing Liu, Liqing Liu, Jingjing Song, Jingjing Song, Jingjing Song, Tian Feng, Tian Feng, Tian Feng, Yihan Li, Yihan Li, Yihan Li, Chao Shen, Lingbao Kong, Lingbao Kong, Lingbao Kong, Xiu Xin, Xiu Xin, Xiu Xin   +24 more
doaj   +1 more source

Molecular Epidemiology of Foot-and-Mouth Disease Virus in Tanzania during 2020 to 2021 Outbreaks [PDF]

Journal of Veterinary Medical Research
Background: Food and mouth disease (FMD) is an endemic disease of cattle and other clovenhoofed animals. The objective of this study was to investigate the genetic characteristics and evolutionary relationships for the 2020 to 2021 field circulating Food
Mkama Mashinagu, Philemon Wambura, Sharadhuli Kimera, Donald King, David Paton, Francois Maree, Herbertha Mpete, Sengiyumva Kandusi, Mark Rweyemamu, Christopher Kasanga   +9 more
doaj   +1 more source

Efficient Extracellular Production of Insulin Glargine in Trichoderma reesei by an Integrative Secretion‐Based Strategy

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
Schematic diagram showing how optimisation of the expression cassette enhances secretory production of insulin Glargine. ABSTRACT Insulin glargine, a long‐acting insulin analog, is essential for diabetes treatment. However, its industrial production remains challenging due to limitations in conventional expression systems.
Aiqin Yan, Xihai Li, Di Zhang, Lunbo Li, Jinfeng Liu, Xuejian Si, Kewen Li, Qingmin Luan, Hong Liu, Yaohua Zhong   +9 more
wiley   +1 more source

Peptides Interfering 3A Protein Dimerization Decrease FMDV Multiplication

PLOS ONE, 2015
Nonstructural protein 3A is involved in relevant functions in foot-and-mouth disease virus (FMDV) replication. FMDV 3A can form homodimers and preservation of the two hydrophobic α-helices (α1 and α2) that stabilize the dimer interface is essential for virus replication.
González Magaldi, Mónica, Vázquez Calvo, Ángela, Torre, Beatriz G. de la, Valle, Javier, Andreu Martínez, David, Sobrino, Francisco   +5 more
openaire   +6 more sources

Plant‐Derived Viral Nanoparticles Enable Simultaneous Guidance of Neuronal Cell Outgrowth and Targeting of Neurodifferentiation Pathways

Small, Volume 22, Issue 1, 2 January 2026.
A neuronal tissue engineering approach employing plant‐derived viral nanoparticles (VNPs) that have been genetically engineered to display functional peptides is presented. These VNPs simultaneously promote neuronal differentiation and directional growth.
Mira Ritter, Natalija Stojanović, Simon Zschieschang, Johannes Grader, MHD Naeem Assasa, Eva Miriam Buhl, Andrea Coschiera, Stefan Schillberg, Juliane Schuphan, Horst Fischer   +9 more
wiley   +1 more source

Diagnostic Overview of Foot-And-Mouth Disease Viruse (FMDV)

South Asian Research Journal of Agriculture and Fisheries, 2023
Foot-and-mouth disease (FMD) is one of the highly contagious diseases of domestic animals. Sensitive, specific, and quick detection of FMD virus antigens and antibodies is an essential corner stone diagnostic tool at each tier of control strategy. Continued development of molecular and genetic technologies combined with novel analytical techniques will ...
Ephrem Shimelis, Shimels Tesfaye, Fanos Tadesse   +2 more
openaire   +1 more source

Foot-and-mouth disease virus (FMDV) with a stable FLAG epitope in the VP1 G-H loop as a new tool for studying FMDV pathogenesis

Virology, 2013
Foot-and-mouth disease virus (FMDV) VP1 G-H loop contains the major antigenic site. By replacing the sequence upstream of the RGD motif with a FLAG epitope, a marker virus for pathogenesis studies was generated. In cell culture, the recombinant virus containing FLAG (A24-FLAG) exhibited similar plaque phenotypes and growth kinetics to parental virus ...
Lawrence, P, Pacheco, J, Uddowla, S, Hollister, J, Kotecha, A, Fry, E, Rieder, E   +6 more
openaire   +3 more sources

Development of gold nanoparticles biosensor for ultrasensitive diagnosis of foot and mouth disease virus

Journal of Nanobiotechnology, 2018
Background Nano-PCR is a recent tool that is used in viral diseases diagnosis. The technique depends on the fundamental effects of gold nanoparticles (AuNPs) and is considered a very effective and sensitive tool in the diagnosis of different diseases ...
Mervat E. Hamdy, Michele Del Carlo, Hussein A. Hussein, Taher A. Salah, Ayman H. El-Deeb, Mohamed M. Emara, Guilia Pezzoni, Dario Compagnone   +7 more
doaj   +1 more source

Advances in Foot-and-Mouth Disease Virus Proteins Regulating Host Innate Immunity

Frontiers in Microbiology, 2020
Foot-and-mouth disease (FMD) is a highly contagious disease that affects cloven-hoofed animals such as pigs, cattle, and sheep. The disease is caused by the foot-and-mouth disease virus (FMDV) which has a non-enveloped virion with icosahedral symmetry ...
Jiangling Peng, Jiamin Yi, Wenping Yang, Jingjing Ren, Yuan Wen, Haixue Zheng, Dan Li   +6 more
doaj   +1 more source