Results 21 to 30 of about 7,295 (180)

IRES-mediated translation of foot-and-mouth disease virus (FMDV) in cultured cells derived from FMDV-susceptible and -insusceptible animals [PDF]

BMC Veterinary Research, 2016
Foot-and-mouth disease virus (FMDV) possess a positive sense, single stranded RNA genome. Internal ribosomal entry site (IRES) element exists within its 5' untranslated region (5'UTR) of the viral RNA. Translation of the viral RNA is initiated by internal entry of the 40S ribosome within the IRES element. This process is facilitated by cellular factors
Kanda, Takehiro, Ozawa, Makoto, Tsukiyama-Kohara, Kyoko   +2 more
openaire   +2 more sources

Protein Coexpression Using FMDV 2A: Effect of “Linker” Residues [PDF]

BioMed Research International, 2013
Many biomedical applications absolutely require, or are substantially enhanced by, coexpression of multiple proteins from a single vector. Foot-and-mouth disease virus 2A (F2A) and “2A-like” sequences (e.g.,Thosea asignavirus 2A; T2A) are used widely for this purpose since multiple proteins can be coexpressed by linking open reading frames (ORFs) to ...
Minskaia, Ekaterina, Ryan, Martin D.
openaire   +4 more sources

Cloning and expression of non-structural 3ABC gene from FMD virus serotype O in Escherichia coli [PDF]

مجله بیوتکنولوژی کشاورزی, 2015
After about one hundred year after its identification, Foot and Mouth Disease (FMD) is the first viral disease in animals that impose a major risk to  the world's livestock industry.
Seyyed Amir Reza Parizadeh, Mohmmad Reza Nasiri, Saeid Zibaei, Mojtaba Tahmoures Pour, Mohmmad Reza Basami   +4 more
doaj   +1 more source

Viral Protein 1 (VP1) Sequence-Based Genetic Diversity of SAT 2 FMDV Circulating in Ethiopia from 1990 to 2015

Veterinary Medicine: Research and Reports, 2023
Fanos Woldemariyam,1,2 Jan Paeshuyse1 1Laboratory of Host-Pathogen Interaction, Division of Animal and Human Health Engineering, Department of Biosystems, KU Leuven, Leuven, Belgium; 2Department of Biomedical Sciences, College of Veterinary Medicine ...
Woldemariyam F, Paeshuyse J
doaj  

Comparative expression analysis of inflammatory and immune-related genes in cattle during acute infection with foot-and-mouth disease virus in Egypt

Journal of Veterinary Research, 2021
Foot-and-mouth disease is a highly infectious viral disease affecting all cloven-footed domestic animals. The three foot-and-mouth disease virus (FMDV) serotypes A, O and SAT2 are at present the greatest threat to susceptible animals in Egypt. The aim of
El Nahas Abeer F., Abd El Naby Walaa S.H., Khatab Shymaa A., Fergany Al-Zahraa A., Rashed Rashed R.   +4 more
doaj   +1 more source

The pH stability of foot-and-mouth disease virus

Virology Journal, 2017
ᅟ This review summarized the molecular determinants of the acid stability of FMDV in order to explore the uncoating mechanism of FMDV and improve the acid stability of vaccines.
Hong Yuan, Pinghua Li, Xueqing Ma, Zengjun Lu, Pu Sun, Xingwen Bai, Jing Zhang, Huifang Bao, Yimei Cao, Dong Li, Yuanfang Fu, Yingli Chen, Qifeng Bai, Jie Zhang, Zaixin Liu   +14 more
doaj   +1 more source

Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms

Frontiers in Immunology, 2018
Foot-and-mouth disease (FMD) is a highly contagious, severe viral illness notifiable to the World Organization for Animal Health. The causative agent, FMD virus (FMDV), replicates rapidly and efficiently inhibits host translation and the innate immune ...
Xu Ye, Xu Ye, Ting Pan, Ting Pan, Dang Wang, Dang Wang, Liurong Fang, Liurong Fang, Jun Ma, Jun Ma, Xinyu Zhu, Xinyu Zhu, Yanling Shi, Yanling Shi, Keshan Zhang, Haixue Zheng, Huanchun Chen, Huanchun Chen, Kui Li, Shaobo Xiao, Shaobo Xiao   +20 more
doaj   +1 more source

The Application of the Gibson Assembly Method in the Production of Two pKLS3 Vector-Derived Infectious Clones of Foot-and-Mouth Disease Virus

Vaccines, 2023
The construction of a full-length infectious clone, essential for molecular virological study and vaccine development, is quite a challenge for viruses with long genomes or possessing complex nucleotide sequence structures.
Ploypailin Semkum, Nattarat Thangthamniyom, Penpitcha Chankeeree, Challika Keawborisuth, Sirin Theerawatanasirikul, Porntippa Lekcharoensuk   +5 more
doaj   +1 more source

The Carrier Conundrum; A Review of Recent Advances and Persistent Gaps Regarding the Carrier State of Foot-and-Mouth Disease Virus

Pathogens, 2020
The existence of a prolonged, subclinical phase of foot-and-mouth disease virus (FMDV) infection in cattle was first recognized in the 1950s. Since then, the FMDV carrier state has been a subject of controversy amongst scientists and policymakers.
Carolina Stenfeldt, Jonathan Arzt
doaj   +1 more source

The High Immunity Induced by the Virus-Like Particles of Foot-and-Mouth Disease Virus Serotype O

Frontiers in Veterinary Science, 2021
Foot-and-mouth disease (FMD), caused by FMD virus (FMDV), is a highly contagious and economically devastating viral disease of cloven-hoofed animals worldwide.
Yan Xiao, Yan Xiao, Suling Zhang, He Yan, Xiaolin Geng, Yanwei Wang, Xin Xu, Mengyue Wang, Haohao Zhang, Baicheng Huang, Wenqiang Pang, Ming Yang, Kegong Tian, Kegong Tian   +13 more
doaj   +1 more source