Results 31 to 40 of about 10,541 (227)

Characterization of expressed FMDV capsid proteins. [PDF]

, 2016
(A) Uninfected BHK cells (control, lane 1) or cells infected with rSFV (lane 2), rSFV-FMDV-P1-2A (lane 3), rSFV-FMDV-P1-2A-3CC142S (lane 4) or rSFV-FMDV-P1-2A-mIRES-3C (lane 5) were harvested and the cell lysates were fractionated by SDS–PAGE.
Graham J. Belsham (116715), Alison Burman (395426), Anette Bøtner (72594), Terry Jackson (363618), Charlotta Polacek (17305), Louise Lohse (2832977), Maria Gullberg (380560), Gerald M. McInerney (250016)   +7 more
core   +1 more source

Comparative expression analysis of inflammatory and immune-related genes in cattle during acute infection with foot-and-mouth disease virus in Egypt

Journal of Veterinary Research, 2021
Foot-and-mouth disease is a highly infectious viral disease affecting all cloven-footed domestic animals. The three foot-and-mouth disease virus (FMDV) serotypes A, O and SAT2 are at present the greatest threat to susceptible animals in Egypt. The aim of
El Nahas Abeer F., Abd El Naby Walaa S.H., Khatab Shymaa A., Fergany Al-Zahraa A., Rashed Rashed R.   +4 more
doaj   +1 more source

Structure of the FMDV translation initiation site and of the structural proteins [PDF]

Nucleic Acids Research, 1983
A cDNA clone of Foot and Mouth Diseases Virus (FMDV), strain C1, has been sequenced. The limits of the structural genes were defined by comparison with the available protein data. We identified two potential translation initiation sites for the viral polyprotein separated by 84 nucleotides.
E, Beck, S, Forss, K, Strebel, R, Cattaneo, G, Feil   +4 more
openaire   +2 more sources

Detection of FMDV serotypes using truncated, His-tagged bovine αvβ6 with anti-FMDV monoclonal antibodies. [PDF]

, 2016
Wells were coated with purified, His-tagged αvβ6 and incubated with viruses representative of the different FMDV serotypes (Panels A-G as indicated). FMDV was detected using a range of FMDV serotype-specific MAbs (see methods for antibody details).
Gareth Shimmon (3142221), Stephen Berryman (3142212), Donald P. King (116717), Britta A. Wood (2918993), Alison Burman (395426), Terry Jackson (363618), Toby Tuthill (3142215), Alison Morris (371631), Valerie Mioulet (3142218), Emiliana Brocchi (845655), Santina Grazioli (845653)   +10 more
core   +1 more source

Viral Protein 1 (VP1) Sequence-Based Genetic Diversity of SAT 2 FMDV Circulating in Ethiopia from 1990 to 2015

Veterinary Medicine: Research and Reports, 2023
Fanos Woldemariyam,1,2 Jan Paeshuyse1 1Laboratory of Host-Pathogen Interaction, Division of Animal and Human Health Engineering, Department of Biosystems, KU Leuven, Leuven, Belgium; 2Department of Biomedical Sciences, College of Veterinary Medicine ...
Woldemariyam F, Paeshuyse J
doaj  

Conserved Linear Epitopes in the VP1 Protein of Foot-and-Mouth Disease Virus Serotype SAT2: Identification and Characterization. [PDF]

Transbound Emerg Dis
Foot‐and‐mouth disease virus (FMDV) serotype Southern African Territories 2 (SAT2), historically endemic to sub‐Saharan Africa, has recently expanded its geographical range to the Middle East, posing a significant transboundary threat to global livestock industries.
Zhu YQ, Shi XT, Burman A, Shi ZW, Xi T, Liao HC, Luo JC, Chen J, Wang L, Xie YG, Yang QQ, Tian H, Zheng HX, King DP.   +13 more
europepmc   +2 more sources

Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms

Frontiers in Immunology, 2018
Foot-and-mouth disease (FMD) is a highly contagious, severe viral illness notifiable to the World Organization for Animal Health. The causative agent, FMD virus (FMDV), replicates rapidly and efficiently inhibits host translation and the innate immune ...
Xu Ye, Xu Ye, Ting Pan, Ting Pan, Dang Wang, Dang Wang, Liurong Fang, Liurong Fang, Jun Ma, Jun Ma, Xinyu Zhu, Xinyu Zhu, Yanling Shi, Yanling Shi, Keshan Zhang, Haixue Zheng, Huanchun Chen, Huanchun Chen, Kui Li, Shaobo Xiao, Shaobo Xiao   +20 more
doaj   +1 more source

The pH stability of foot-and-mouth disease virus

Virology Journal, 2017
ᅟ This review summarized the molecular determinants of the acid stability of FMDV in order to explore the uncoating mechanism of FMDV and improve the acid stability of vaccines.
Hong Yuan, Pinghua Li, Xueqing Ma, Zengjun Lu, Pu Sun, Xingwen Bai, Jing Zhang, Huifang Bao, Yimei Cao, Dong Li, Yuanfang Fu, Yingli Chen, Qifeng Bai, Jie Zhang, Zaixin Liu   +14 more
doaj   +1 more source

Foot-and-mouth disease virus VP1 target the MAVS to inhibit type-I interferon signaling and VP1 E83K mutation results in virus attenuation.

PLoS Pathogens, 2020
VP1, a pivotal capsid protein encoded by the foot-and-mouth disease virus (FMDV), plays an important role in receptor-mediated attachment and humoral immune responses.
Pathum Ekanayaka, Seo-Yong Lee, Thilina U B Herath, Jae-Hoon Kim, Tae-Hwan Kim, Hyuncheol Lee, Kiramage Chathuranga, W A Gayan Chathuranga, Jong-Hyeon Park, Jong-Soo Lee   +9 more
doaj   +1 more source

The Carrier Conundrum; A Review of Recent Advances and Persistent Gaps Regarding the Carrier State of Foot-and-Mouth Disease Virus

Pathogens, 2020
The existence of a prolonged, subclinical phase of foot-and-mouth disease virus (FMDV) infection in cattle was first recognized in the 1950s. Since then, the FMDV carrier state has been a subject of controversy amongst scientists and policymakers.
Carolina Stenfeldt, Jonathan Arzt
doaj   +1 more source