Direct detection and characterization of foot-and-mouth disease virus in East Africa using a field-ready real-time PCR platform [PDF]
, 2017 Effective control and monitoring of foot-and-mouth disease (FMD) relies upon rapid and accurate disease confirmation. Currently, clinical samples are usually tested in reference laboratories using standardized assays recommended by The World Organisation
Armson, B. +16 more
core +1 more source
Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context. [PDF]
, 2008 Engineered RNAs carrying substitutions in the integrin receptor-binding Arg-Gly-Asp (RGD) region of foot-and-mouth disease virus (FMDV) were constructed (aa 141-147 of VP1 capsid protein) and their infectivity was assayed in cultured cells and suckling
Baranowski, Eric +4 more
core +3 more sources
Plant-produced viral bovine vaccines: What happened during the last ten years? [PDF]
, 2015 Vaccination has proved to be an efficient strategy to deal with viral infections in both human and animal species. However, protection of cattle against viral infections is still a major concern in veterinary science.
Dus Santos, María José +3 more
core +1 more source
Complete genome sequences of three African foot-and-mouth disease viruses from clinical samples isolated in 2009 and 2010 [PDF]
, 2016 <p>The complete genome sequences of three foot-and-mouth disease viruses (one virus of each serotype SAT1, SAT2 and O) were directly sequenced from RNA extracted from clinical bovine samples, demonstrating the feasibility of full-genome sequencing ...
De Clercq, Kris +8 more
core +1 more source
The High Immunity Induced by the Virus-Like Particles of Foot-and-Mouth Disease Virus Serotype O
Frontiers in Veterinary Science, 2021 Foot-and-mouth disease (FMD), caused by FMD virus (FMDV), is a highly contagious and economically devastating viral disease of cloven-hoofed animals worldwide.
Yan Xiao +13 more
doaj +1 more source
Foot-and-mouth disease in Tanzania from 2001 to 2006. [PDF]
, 2010 Foot-and-mouth disease (FMD) is endemic in Tanzania, with outbreaks occurring almost each year in different parts of the country. There is now a strong political desire to control animal diseases as part of national poverty alleviation strategies ...
Berkvens, D +6 more
core +1 more source
Peptides Interfering 3A Protein Dimerization Decrease FMDV Multiplication
PLOS ONE, 2015 Nonstructural protein 3A is involved in relevant functions in foot-and-mouth disease virus (FMDV) replication. FMDV 3A can form homodimers and preservation of the two hydrophobic α-helices (α1 and α2) that stabilize the dimer interface is essential for virus replication.
González Magaldi, Mónica +5 more
openaire +6 more sources
IRES-mediated translation of foot-and-mouth disease virus (FMDV) in cultured cells derived from FMDV-susceptible and -insusceptible animals [PDF]
BMC Veterinary Research, 2016 Foot-and-mouth disease virus (FMDV) possess a positive sense, single stranded RNA genome. Internal ribosomal entry site (IRES) element exists within its 5' untranslated region (5'UTR) of the viral RNA. Translation of the viral RNA is initiated by internal entry of the 40S ribosome within the IRES element. This process is facilitated by cellular factors
Kanda, Takehiro +2 more
openaire +2 more sources
Frontiers in Cellular and Infection Microbiology, 2021 Endoplasmic reticulum (ER) stress-induced autophagy is closely associated with viral infection and propagation. However, the intrinsic link between ER stress, autophagy, and viral replication during foot-and-mouth disease virus (FMDV) infection is not ...
Jin’en Wu +6 more
doaj +1 more source
UK Foot and Mouth disease: a systemic risk assessment of existing controls [PDF]
, 2016 This article details a systemic analysis of the controls in place and possible interventions available to further reduce the risk of a foot and mouth disease (FMD) outbreak in the United Kingdom.
Longhurst, Philip J. +2 more
core +1 more source