Results 31 to 40 of about 7,295 (180)

Pathogenesis of virulent and attenuated foot-and-mouth disease virus in cattle

Virology Journal, 2017
Background Understanding the mechanisms of attenuation and virulence of foot-and-mouth disease virus (FMDV) in the natural host species is critical for development of next-generation countermeasures such as live-attenuated vaccines.
Jonathan Arzt, Juan M. Pacheco, Carolina Stenfeldt, Luis L. Rodriguez   +3 more
doaj   +1 more source

Foot-and-mouth disease virus VP1 target the MAVS to inhibit type-I interferon signaling and VP1 E83K mutation results in virus attenuation.

PLoS Pathogens, 2020
VP1, a pivotal capsid protein encoded by the foot-and-mouth disease virus (FMDV), plays an important role in receptor-mediated attachment and humoral immune responses.
Pathum Ekanayaka, Seo-Yong Lee, Thilina U B Herath, Jae-Hoon Kim, Tae-Hwan Kim, Hyuncheol Lee, Kiramage Chathuranga, W A Gayan Chathuranga, Jong-Hyeon Park, Jong-Soo Lee   +9 more
doaj   +1 more source

Molecular characterization and VP1 sequence analysis of Foot and Mouth disease new virus strains isolated during 2015-2017 in Beni-Suef, Egypt [PDF]

Journal of Veterinary Medical Research, 2018
Outbreaks of Foot and Mouth Disease (FMD) cause severe economic loss to the livestock industries in terms of loss of meat, milk production and the high mortality rateespecially in calves.
Amany T. El-Gendy, Abdel-Hamid Bazid, Hanafy M. Madbouly, S.M. Tamam   +3 more
doaj   +1 more source

DIFFERENTIATION BETWEEN FOOT AND MOUTH DISEASE VIRUS INFECTED AND VACCINATED CATTLE USING RECENT TECHNIQUES [PDF]

Assiut Veterinary Medical Journal, 2005
To study the possibility of differentiation between foot and mouth disease virus (FMDV) vaccinated and infected cattle, 100 cattle were used, 70 of them were non vaccinated while the remainder 30 were vaccinated against FMDV.
U. ABD EL HAKIM
doaj   +1 more source

Sec62 Regulates Endoplasmic Reticulum Stress and Autophagy Balance to Affect Foot-and-Mouth Disease Virus Replication

Frontiers in Cellular and Infection Microbiology, 2021
Endoplasmic reticulum (ER) stress-induced autophagy is closely associated with viral infection and propagation. However, the intrinsic link between ER stress, autophagy, and viral replication during foot-and-mouth disease virus (FMDV) infection is not ...
Jin’en Wu, Zhihui Zhang, Zhidong Teng, Sahibzada Waheed Abdullah, Shiqi Sun, Huichen Guo, Huichen Guo   +6 more
doaj   +1 more source

Sensitivity of specimen type for diagnosing foot-and-mouth diseases in cattle using one-step real-time polymerase chain reaction (3D gene)

Open Veterinary Journal
Background: Indonesia is currently experiencing a foot and mouth disease (FMD) outbreak in livestock, caused by the foot and mouth disease virus. FMDV is easily spread to cause outbreaks in new geographical locations. Identifying Foot and mouth diseases
Siswani Siswani, Mochammad Hatta, Muflihanah Muflihanah, Nurul Muslinah Muhiddin, Fitrine Ekawasti, Rini Damayanti, Riza Zainuddin Ahmad, Putri Reno Intan, Fitriana Fitriana, Muhammad Ibrahim Desem, Ratih Rinendyaputri   +10 more
doaj   +1 more source

Development of Foot-and-Mouth Disease Virus-Neutralizing Monoclonal Antibodies Derived From Plasmablasts of Infected Cattle and Their Germline Gene Usage

Frontiers in Immunology, 2019
Cattle are susceptible to foot-and-mouth disease virus (FMDV), and neutralizing antibodies are critical for protection against FMDV infection in this species.
Kun Li, Sheng Wang, Yimei Cao, Huifang Bao, Pinghua Li, Pu Sun, Xingwen Bai, Yuanfang Fu, Xueqing Ma, Jing Zhang, Dong Li, Yingli Chen, Xuerong Liu, Fanglan An, Faju Wu, Zengjun Lu, Zaixin Liu   +16 more
doaj   +1 more source

Foot-and-Mouth Disease Virus 3C Protease Antagonizes Interferon Signaling and C142T Substitution Attenuates the FMD Virus

Frontiers in Microbiology, 2021
3C protease (3Cpro), a chymotrypsin-like cysteine protease encoded by the foot-and-mouth disease virus (FMDV), plays an essential role in processing the FMDV P1 polyprotein into individual viral capsid proteins in FMDV replication.
Pathum Ekanayaka, Sung Ho Shin, Prasanna Weeratunga, Hyuncheol Lee, Hyuncheol Lee, Tae-Hwan Kim, Tae-Hwan Kim, Kiramage Chathuranga, Ashan Subasinghe, Jong-Hyeon Park, Jong-Soo Lee   +10 more
doaj   +1 more source

FMDV RNA packaging and capsid assembly

, 2021
Foot-and-mouth disease virus (FMDV), of the Picornaviridae family, is a non-enveloped, single-stranded, positive-sense RNA virus. FMDV infects cloven-hooved animals and is an important pathogen for global agriculture due to the economic consequences of both endemic disease and epidemic outbreaks.
openaire   +2 more sources

Efficacy of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine in cattle using a direct contact transmission model

BMC Veterinary Research, 2018
Background A direct contact transmission challenge model was used to simulate natural foot-and-mouth disease virus (FMDV) spread from FMDV A24/Cruzeiro/BRA/55 infected ‘seeder’ steers to naïve or vaccinated steers previously immunized with a replication ...
John G. Neilan, Christopher Schutta, José Barrera, Melia Pisano, Laszlo Zsak, Ethan Hartwig, Max V. Rasmussen, Barbara J. Kamicker, Damodar Ettyreddy, Douglas E. Brough, Bryan T. Butman, David A. Brake   +11 more
doaj   +1 more source