Results 91 to 100 of about 10,661 (224)
Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/p38MAPKα-dependent mechanisms [PDF]
Jing Ma +12 more
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Regulation of Cellular Stress Signaling in Bladder Ischemia
Jing-Hua Yang,1 Yedan Li,2 Roya Azad,2 Kazem Azadzoi3 1Department of Surgery, Boston University School of Medicine, Boston, MA, USA; 2Department of Urology, VA Boston Healthcare System, Boston, MA, USA; 3Department of Urology and Department of Pathology,
Yang J, Li Y, Azad R, Azadzoi K
doaj
ASK1 and Its Role in Neurodegenerative Diseases
The apoptosis signal-regulating kinase 1 (ASK1) is a ubiquitously expressed serine/threonine protein kinase and one of more than 20 members that make up the triple MAP kinase (MAP3K) family of enzymes. Over the past decade, genetic studies have revealed that ASK1 plays a pivitol role in the cellular response to a wide variety of environmental and ...
Sturchler, Emmanuel +3 more
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Induction of Apoptosis Signal Regulating Kinase 1 (ASK1) after Spinal Cord Injury in Rats [PDF]
Shinji Nakahara +6 more
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ASK1: A Therapeutic Target for the Treatment of Multiple Diseases
Ahmed F. Abdel‐Magid
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Targeting ASK1 by CS17919 alleviates kidney‐ and liver‐related diseases in murine models
Background Apoptosis signal‐regulating kinase 1 (ASK1) is a MAP3K kinase in the MAPK signaling pathway activated by stressors and triggers downstream biological effects such as inflammation and apoptosis; therefore, inhibition of ASK1 kinase activity can
Guoqiang Liao +9 more
doaj +1 more source

