Results 101 to 110 of about 10,661 (224)

Ask1 and Akt act synergistically to promote ROS-dependent regeneration in Drosophila

, 2019
Paula Santabárbara-Ruiz, José Esteban-Collado, Lídia Pérez, Giacomo Viola, Josep F. Abril, Marco Milán, Montserrat Corominas, Florenci Serras   +7 more
openalex   +2 more sources

Inhibition of HDAC4 by GSK3β leads to downregulation of KLF5 and ASK1 and prevents the progression of intravertebral disc degeneration [PDF]

, 2021
Xiao Lin, Dongping Gong, Loufeng Liang, Anwei Liang, Huaxin Liang, Xiayi Xu, Hongli Teng   +6 more
openalex   +1 more source

Abrogating PDK4 activates autophagy-dependent ferroptosis in breast cancer via ASK1/JNK pathway [PDF]

Wenbiao Shi, Jian Wang, Jianbin Chen, Xiaoyan Jin, Yuanfan Wang, Linjun Yang   +5 more
openalex   +1 more source

Zinc finger protein ZPR9 functions as an activator of AMPK-related serine/threonine kinase MPK38/MELK involved in ASK1/TGF-β/p53 signaling pathways [PDF]

, 2017
Hyun‐A Seong, Ravi Manoharan, Hyunjung Ha   +2 more
openalex   +1 more source

<p>Theabrownin Induces Apoptosis and Tumor Inhibition of Hepatocellular Carcinoma Huh7 Cells Through ASK1-JNK-c-Jun Pathway</p>

, 2020
Jiaan Xu, Bo Yan, Lei Zhang, Li Zhou, Jin Zhang, Wenhua Yu, Xiao‐Qiao Dong, Yao Li, Letian Shan   +8 more
openalex   +2 more sources

<p>Ox-LDL Causes Endothelial Cell Injury Through ASK1/NLRP3-Mediated Inflammasome Activation via Endoplasmic Reticulum Stress</p> [PDF]

, 2020
Liwei Hang, Yan Peng, Rui Xiang, Xiangdong Li, Zhiliang Li   +4 more
openalex   +1 more source

Structural study of the ASK1:thioredoxin complex

, 2017
The mitogen-activated protein kinase (MAPK) cascade is an essential member of the cell defense system against stressors. The capability and efficiency of the cell reactions to different stress signals depend on signal transduction pathway, where signals from MAPK kinase kinase (MAP3K) are transferred through phosphorylation to downstream MAPK kinase ...
openaire   +2 more sources

Mechanism of cooperative strigolactone perception by the MAX2 ubiquitin ligase-receptor-substrate complex. [PDF]

Nat Commun
Vancea AI, Huntington B, Steinchen W, Savva CG, Shahul Hameed UF, Arold ST.   +5 more
europepmc   +1 more source

Retraction: The angiotensin receptor neprilysin inhibitor LCZ696 attenuates renal fibrosis via ASK1/JNK/p38 MAPK-mediated apoptosis in unilateral ureteral obstruction. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3 character and an exquisite selectivity profile

, 2020
Simone V. Bigi-Botterill, Anthony Ivetac, Erica L. Bradshaw, Derek C. Cole, Douglas R. Dougan, Jacques Ermolieff, Petro Halkowycz, Ben Johnson, Christopher M. McBride, Jason Pickens, M. Sabat, Steven Swann   +11 more
openalex   +1 more source