Results 71 to 80 of about 10,661 (224)
Eucalyptol antagonized the apoptosis and immune dysfunction of grass carp hepatocytes induced by tetrabromobisphenol
, 2023 Wenying Sun +4 more
openalex +1 more source
MedComm, Volume 6, Issue 12, December 2025.Radiation‐induced biological effects are an extremely complex and extensive mechanism that involves multiple aspects of physiological activities in organisms. In the medical field, utilizing the damaging effects of radiation to treat tumors is a commonly employed therapeutic approach.
Zhihe Hu +5 more
wiley +1 more source
Cells, 2019 The ASK1-signalosome→p38 MAPK and SAPK/JNK signaling networks promote senescence (in vitro) and aging (in vivo, animal models and human cohorts) in response to oxidative stress and inflammation.
John Papaconstantinou
doaj +1 more source
MedComm, Volume 6, Issue 12, December 2025.Protein arginine methyltransferase 1 (PRMT1) is a pivotal enzyme that catalyzes the asymmetric dimethylation of arginine residues, thereby functioning as a critical epigenetic regulator of diverse biological processes such as gene expression, RNA splicing, and DNA repair.
Yanqun Luo +4 more
wiley +1 more source
E3 Ubiquitin Ligases: Structures, Biological Functions, Diseases, and Therapy
MedComm, Volume 6, Issue 12, December 2025.E3 ligases function as critical regulators of cellular protein degradation, and their dysregulation is a core pathogenic mechanism in a wide array of human diseases, including cancer, cardiovascular conditions, neurodegenerative disorders, and autoimmune diseases.
Haochen Wang +6 more
wiley +1 more source
Mediators of Inflammation, 2020 Background. Apoptosis signal-regulating kinase 1 (ASK1) has been reported to induce fibrotic signaling in the setting of oxidative stress. However, the role of ASK1 and its mechanism of action in angiotensin II- (Ang II-) induced liver fibrosis remain ...
Pei-pei Fang +7 more
doaj +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.Hypoxia induces HMGB1's nucleus‐to‐cytoplasm translocation, which binds to Nrf2 to repress Nrf2 nuclear translocation to suppress Nrf2/HO‐1 activation to promote NLRP3 inflammasome/Caspase‐1‐mediated pyroptosis, thereby exacerbating MIRI. ABSTRACT Objective Myocardial ischemia–reperfusion injury (MIRI) represents an inevitable risk event for acute ...
Fuzhen Zheng +7 more
wiley +1 more source
Scientific Reports, 2017 Alveolar type II epithelial cells (ATII) are instrumental in early wound healing in response to lung injury, restoring epithelial integrity through spreading and migration. We previously reported in separate studies that focal adhesion kinase-1 (FAK) and
Manik C. Ghosh +6 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2017 Inflammation is implicated in ischemic stroke and is involved in abnormal homeostasis. Activation of the immune system leads to breakdown of the blood–brain barrier and, thereby, infiltration of immune cells into the brain.
So Yeong Cheon +10 more
doaj +1 more source