Results 131 to 140 of about 321,777 (218)

Linking probable respiratory sarcopenia to frailty in older adults: A cross-sectional and longitudinal analysis. [PDF]

Medicine (Baltimore)
Wu M, Cao F, Huang Y, Chen K, Ding P.
europepmc   +1 more source

Comparative multicenter evaluation of thalamic neuromodulation for treatment‐resistant epilepsy in children

Epilepsia, EarlyView.
Abstract Objective Use of neuromodulation strategies targeting thalamic nuclei, including deep brain stimulation (DBS) and responsive neurostimulation (RNS), for treatment of pediatric drug‐resistant epilepsy (DRE) is increasing, despite limited evidence for efficacy and safety. We present the initial results from the Comparative Multicenter Evaluation
Samuel A. Tenhoeve, Nebras M. Warsi, Allison M. Ludwick, Adam C. Glaser, Marcella R. Ruppert‐Gomez, Scellig S. Stone, Megan Votoupal, Jeffrey S. Raskin, Shanique Doyle, Benjamin Kennedy, Deborah Grenard, Dominic Nistal, Hannah E. Goldstein, Jason S. Hauptman, Gavin Yoon, Kurtis I. Auguste, David D. Gonda, Alon Kashanian, Shaun D. Rodgers, Janette Coble, Jarod L. Roland, Nunthasiri Wittayanakorn, Chima O. Oluigbo, Somnath Das, Jasmine A. Thum, Carolina Gorodetsky, MyLoi Huynh, George M. Ibrahim, Robert J. Bollo   +28 more
wiley   +1 more source

Emergency treatment delay and underdosing are associated with poor outcome in non-convulsive status epilepticus. [PDF]

Epilepsia
Misirocchi F, Ballabeni A, Frapporti M, Borgna A, Zinno L, Meletti S, Florindo I.   +6 more
europepmc   +1 more source

Refining diagnostic boundaries and electroclinical profiles of Lennox–Gastaut syndrome through unsupervised clustering

Epilepsia, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a developmental and epileptic encephalopathy defined by polymorphic seizures, intellectual disability (ID), and characteristic electroencephalographic (EEG) patterns. The applicability and biological validity of current electroclinical criteria remain debated.
Emanuele Cerulli Irelli, Marco Perulli, Maria S. Borioni, Anna Falco, Adolfo Mazzeo, Enrico Cocchi, Maria L. Gambardella, Alessandra Morano, Michela Quintiliani, Maria Picilli, Anna T. Giallonardo, Carlo Di Bonaventura, Domenica I. Battaglia   +12 more
wiley   +1 more source

Mapping airway smooth muscle remodelling <i>in vivo</i> using polarisation-sensitive optical coherence tomography. [PDF]

ERJ Open Res
Hackmann MJ, Cairncross A, Mulrennan SA, Thomas R, Thakkar D, Elliot JG, Donovan G, McLaughlin RA, Cense B, James AL, Noble PB.   +10 more
europepmc   +1 more source

Acute effects of anti‐seizure medications on network level dynamics: A systematic comparison using multielectrode arrays

Epilepsia, EarlyView.
Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku, Lena Gschossmann, Kerstin Hallmann, Heinz Beck, Kunihiko Araki   +4 more
wiley   +1 more source

Serum vitamin D and B9 are positively associated with muscle mass in young and middle-aged adults: a cross-sectional study. [PDF]

Front Nutr
Liu XP, Sun J, Liu Z, Zhang HF, Chen JW.
europepmc   +1 more source

KIT mutation and AHN-associated oncogenic profiles in systemic mastocytosis with an associated hematological neoplasm. [PDF]

Blood Adv
Navarro-Navarro P, Fernández-Giménez CM, García-Montero AC, Álvarez-Twose I, Sánchez-Muñoz L, Henriques A, Pérez-Pons A, González-Tablas M, Teodosio C, González-González M, Matarraz S, López A, Barcena P, Colado E, Esteve J, Senent ML, González-López Ó, Mollejo M, Morales-Cabeza C, Jara-Acevedo M, Orfao A.   +20 more
europepmc   +1 more source

Antiseizure potency and neurotoxicity of the enantiomers of fenfluramine and norfenfluramine in rats and correlations with their concentrations in plasma and brain

Epilepsia, EarlyView.
Abstract Objective Based on the evidence that fenfluramine‐induced anorexia, weight loss, and cardiovascular toxicity are primarily mediated by the d‐enantiomers of fenfluramine and its metabolite norfenfluramine, we investigated pharmacokinetic/pharmacodynamic correlations for the active enantiomers of fenfluramine and norfenfluramine in the rat ...
Yara Sheeni, Dinorah Barasch, Tawfeeq Shekh‐Ahmad, Emilio Perucca, Meir Bialer   +4 more
wiley   +1 more source

Optimizing polytherapy management for Dravet syndrome in the United States: A National Expert Consensus. [PDF]

Epilepsia Open
Wirrell E, Sullivan J.
europepmc   +1 more source