Results 141 to 150 of about 321,777 (218)

Perils and progress in epilepsy surgery utilization: Twenty‐five years later

Epilepsia, EarlyView.
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley   +1 more source

Sustained seizure reduction, treatment simplification, and high retention with cenobamate: A 12-month real-world study in refractory and ultra-refractory focal epilepsy. [PDF]

Epilepsia Open
Cutropia F, Di Claudio MT, Robustella M, Costantino U, Ferro CP, Miscio G, Conte E, Amoroso N, Nicolotti O, Altomare CD, Carella M, Liantonio A, Imbrici P, d'Orsi G.   +13 more
europepmc   +1 more source

Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms

Epilepsia, EarlyView.
Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong, Ewan S. Nurse, Ashley Reynolds, Mark J. Cook, Philippa J. Karoly   +4 more
wiley   +1 more source

Long‐term prediction of epilepsy following traumatic brain injury among veterans using routine clinical data

Epilepsia, EarlyView.
Abstract Objective Despite elevated risk for epilepsy following traumatic brain injury (TBI), there are limited tools to assess epilepsy risk following TBI using routine clinical data. The objective of this study was to develop and validate a machine learning approach to predict the onset of posttraumatic epilepsy (PTE) over varying time horizons ...
Mustafa Ozmen, Shashank Vadlamani, James J. Gugger, Megan Amuan, Ramon Diaz‐Arrastia, Mary Jo Pugh, Eamonn Kennedy   +6 more
wiley   +1 more source

AhR activation inhibits DRP1-induced mitochondrial fission in airway smooth muscle during asthma. [PDF]

Am J Respir Cell Mol Biol
Reza MI, Tandberg C, Kumar A, Balraj P, Thompson MA, Prakash YS, Pabelick CM, Britt RD, Sathish V.   +8 more
europepmc   +1 more source

A Phase I study of the pharmacokinetics (PK), bioavailability, dose proportionality, safety, and tolerability of topiramate injection compared to Oral topiramate in healthy adult participants

Epilepsia, EarlyView.
Abstract This Phase I study evaluated the safety, tolerability, and pharmacokinetics of a 30‐min topiramate injection (intravenous [IV] TPM) infusion compared with oral topiramate (oral TPM) in healthy adult participants. In this randomized, open‐label, dose escalation, crossover study with 37 healthy participants received single doses of 50, 100, or ...
Adeboye O. Bamgboye, James C. Cloyd, Bernard D. King, Lisa D. Coles   +3 more
wiley   +1 more source

Hypercapnia enhances airway smooth muscle contractility via STIM1-dependent Ca2+ signaling. [PDF]

JCI Insight
Shigemura M, Kryvenko V, Pacheco JA, Puckelwartz MJ, Aleksic M, Magnani ND, Thompson E, Martin-Romero FJ, Cummins EP, Seeger W, Bräuninger A, Welch LC, Budinger GRS, Lecuona E, Dada LA, Bharat A, Vadász I, Prakriya M, Sznajder JI.   +18 more
europepmc   +1 more source

Could calcitonin gene‐related peptide inhibitors prevent status epilepticus?

Epilepsia, EarlyView.
Abstract Calcitonin gene‐related peptide (CGRP) inhibitors modulate pain and neuroinflammation, a recognized contributor to epileptogenesis and status epilepticus (SE). We examined the association between CGRP inhibitor use and SE hospitalization in epilepsy patients with comorbid migraine.
Michael Nsaka, Noor Baban, Sepideh Allahdadian, Armin Scheffler, Diana Lindner, Dagny Holle, Alain Lekoubou   +6 more
wiley   +1 more source

ASM Affairs [PDF]

Microbiology Australia, 2022
doaj  

AI-derived whole-body MRI metrics in patients with multiple myeloma reveal unique insights into body composition and outcomes. [PDF]

Blood Adv
Basty N, Kaiser M, Pawlyn C, Boyd K, Smith K, Thomas K, Porta N, Meo D, Emsley R, Winfield J, Dragan A, Doran S, Koh DM, Whitcher B, Messiou C.   +14 more
europepmc   +1 more source