The impact of non-caloric artificial sweetener aspartame on female reproductive system in mice model [PDF]
Reproductive Biology and Endocrinology, 2023 Background Artificial sweeteners, used as sugar substitutes have found their ways into almost all the food items due to the notion that they are non-caloric. Aspartame is used in numerous food products throughout the world. The primary users of aspartame
Ab Qayoom Naik +2 more
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Aspartame sensitivity? A double blind randomised crossover study.
PLoS ONE, 2015 BackgroundAspartame is a commonly used intense artificial sweetener, being approximately 200 times sweeter than sucrose. There have been concerns over aspartame since approval in the 1980s including a large anecdotal database reporting severe symptoms ...
Thozhukat Sathyapalan +10 more
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Analysis of toxicity and mechanisms of aspartame in kidney stones with network toxicology and molecular docking strategy [PDF]
Scientific ReportsAspartame, an artificial sweetener, has been implicated in the formation of kidney stones, although the underlying mechanisms remain poorly understood.
Kailiang Xu +4 more
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Metagenomics and transcriptomics analysis of aspartame’s impact on gut microbiota and glioblastoma progression in a mouse model [PDF]
Scientific ReportsAspartame, a widely used artificial sweetener, has been extensively studied for its potential health effects. Emerging evidence suggests that aspartame intake may directly impact the composition and function of the intestinal microbiota, which could ...
Kaikai Meng +8 more
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Aspartame and ischemic stroke: unraveling the molecular link through network toxicology and molecular docking analysis [PDF]
Scientific ReportsAspartame, a widely used artificial sweetener, remains controversial due to neurotoxic risks from its metabolites—phenylalanine, aspartic acid, and methanol.
Tianyu Zhang +4 more
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Maternal Aspartame Exposure Induces Neonatal Pulmonary Metabolic Dysregulation and Redox Imbalance: A Multiomics Investigation of Gut Microbiota-Host Interactions. [PDF]
J Agric Food ChemHo SY +4 more
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BioLink, 2022 Aspartame is an artificial sweetener in foods and beverages. Continuous use of aspartame will result in oxidative stress in the liver. So we need antioxidants from outside the body such as periwinkle leaves.This study aims to determine the effect of ...
Mahriani Mahriani +2 more
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Genotoxicity of Aspartame [PDF]
Drug and Chemical Toxicology, 2004 In the present study, the genotoxic effects of the low-calorie sweetener aspartame (ASP), which is a dipeptide derivative, was investigated using chromosome aberration (CA) test, sister chromatid exchange (SCE) test, micronucleus test in human lymphocytes and also Ames/Salmonella/ microsome test.
Rencüzogullari E. +6 more
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Low-dose aspartame consumption differentially affects gut microbiota-host metabolic interactions in the diet-induced obese rat. [PDF]
PLoS ONE, 2014 Aspartame consumption is implicated in the development of obesity and metabolic disease despite the intention of limiting caloric intake. The mechanisms responsible for this association remain unclear, but may involve circulating metabolites and the gut ...
Marie S A Palmnäs +7 more
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Histopathological and the Dose Depended Effects of Aspartame toxicity on Liver and Kidney of Rats [PDF]
Journal of Applied Veterinary Sciences, 2023 Aspartame is a commonly employed artificial sweetener used by hyperglycemic patients and in food management. Its danger depends on the outcome of previous studies that revealed controversy. The purpose of this study was to look into the histopathological
Omar Azez +3 more
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