Results 11 to 20 of about 20,129 (222)

Aspartame sensitivity? A double blind randomised crossover study. [PDF]

PLoS ONE, 2015
BackgroundAspartame is a commonly used intense artificial sweetener, being approximately 200 times sweeter than sucrose. There have been concerns over aspartame since approval in the 1980s including a large anecdotal database reporting severe symptoms ...
Thozhukat Sathyapalan, Natalie J Thatcher, Richard Hammersley, Alan S Rigby, Fraser L Courts, Alexandros Pechlivanis, Nigel J Gooderham, Elaine Holmes, Elaine Holmes, Carel W le Roux, Stephen L Atkin   +10 more
doaj   +8 more sources

Assessment of Aspartame (E951) Occurrence in Selected Foods and Beverages on the German Market 2000–2022

Foods, 2023
This study examines the occurrence of the artificial sweetener aspartame (E951) in foods and beverages sampled by food control authorities in Germany between 2000 and 2022. The dataset was obtained through the Consumer Information Act.
Sydney Schorb, Katharina Gleiss, Roland Wedekind, Eero Suonio, Ann-Kathrin Kull, Marcel Kuntz, Stephan G. Walch, Dirk W. Lachenmeier   +7 more
doaj   +2 more sources

Relationship between Aspartame-Induced Cerebral Cortex Injury and Oxidative Stress, Inflammation, Mitochondrial Dysfunction, and Apoptosis in Sprague Dawley Rats

Antioxidants, 2023
There are emerging concerns about the potential cerebral cortex injury from aspartame due to the accumulation of the various neurotoxic metabolic components in the central nervous system after long-term dietary exposure.
Jureeporn U-pathi, Yen-Chia Yeh, Chia-Wen Chen, Eddy E. Owaga, Rong-Hong Hsieh   +4 more
doaj   +2 more sources

Aspartame increases the risk of liver cancer through CASP1 protein: A comprehensive network analysis insights

Ecotoxicology and Environmental Safety
Background: Aspartame is a widely used artificial sweetener in food and beverages. Its safety concerns and potential carcinogenic risks have garnered increasing attention.
Ni-ren Li, Yi-xuan Zeng, Yu-feng Gu, Pai Xie, Bing-ying Deng, Si-fan Lu, Wang-an Li, Yi Liu   +7 more
doaj   +2 more sources

Effective inhibition of T95 steel corrosion in 15 wt% HCl solution by aspartame, potassium iodide, and sodium dodecyl sulphate mixture

Scientific Reports, 2023
Sustainable development goal 12 advocates the production and consumption of green and sustainable commodities. As such, pressure is mounting on the oil and gas industries for a paradigm shift.
Moses M. Solomon
doaj   +2 more sources

Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells

Biomedicines
Aspartame, a widely used artificial sweetener, is present in many food products and beverages worldwide. It has been linked to potential neurotoxicity and developmental defects.
Athiram Pandaram, Jeyakumari Paul, Wankupar Wankhar, Abhimanyu Thakur, Sakshi Verma, Karthick Vasudevan, Dapkupar Wankhar, Ananth Kumar Kammala, Priyanshu Sharma, Ravindran Jaganathan, Ashok Iyaswamy, Ravindran Rajan   +11 more
doaj   +2 more sources

The impact of non-caloric artificial sweetener aspartame on female reproductive system in mice model

Reproductive Biology and Endocrinology, 2023
Background Artificial sweeteners, used as sugar substitutes have found their ways into almost all the food items due to the notion that they are non-caloric. Aspartame is used in numerous food products throughout the world. The primary users of aspartame
Ab Qayoom Naik, Tabassum Zafar, Vinoy K Shrivastava   +2 more
doaj   +2 more sources

Aspartame carcinogenic potential revealed through network toxicology and molecular docking insights

Scientific Reports
The research employed network toxicology and molecular docking techniques to systematically examine the potential carcinogenic effects and mechanisms of aspartame (l-α-aspartyl-l-phenylalanine methyl ester). Aspartame, a commonly used synthetic sweetener,
Dandan Chen, Xianbing Hou
doaj   +2 more sources

PCN-222 metal–organic framework: a selective and highly efficient sorbent for the extraction of aspartame from gum, juice, and diet soft drink before its spectrophotometric determination

BMC Chemistry, 2020
In this paper, we describe synthesis and application of an iron porphyrinc metal–organic framework PCN-222(Fe) for solid phase extraction of aspartame, an artificial non-saccharine sweetener, from gum, juice and diet soft drink samples prior to its ...
Zahra Safaei Moghaddam, Massoud Kaykhaii, Mostafa Khajeh, Ali Reza Oveisi   +3 more
doaj   +2 more sources

Aspartame Safety as a Food Sweetener and Related Health Hazards

Nutrients, 2023
Aspartame is the methyl-ester of the aspartate-phenylalanine dipeptide. Over time, it has become a very popular artificial sweetener. However, since its approval by the main food safety agencies, several concerns have been raised related to ...
Shurooq Asaad Abdulameer Shaher, D. Mihailescu, B. Amuzescu   +2 more
semanticscholar   +1 more source