Results 91 to 100 of about 240,598 (262)

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Thrombocytopenia in end-stage renal disease and chronic viral hepatitis B or C [PDF]

, 2018
Objectives. We evaluated platelet counts in end-stage renal disease and chronic viral hepatitis. Materials and Methods. We studied 70 patients with end-stage renal disease and chronic viral hepatitis and compared them to a control group of 45 patients ...
Breaban, Iulia, Ciulei, George, Cozma, Angela, Negrean, Vasile, Orasan, Olga Hilda, Orasan, Remus Aurel, Patiu, Ioan Mihai, Sampelean, Dorel, Secara, Sorina Cezara, Sitar Taut, Adela, Stefan, Andreea Maria, Tarmure Sarlea, Simina, Urian, Laura   +12 more
core   +1 more source

Comparative Metabolomics of Early Development of the Parasitic Plants Phelipanche aegyptiaca and Triphysaria versicolor. [PDF]

, 2019
Parasitic weeds of the family Orobanchaceae attach to the roots of host plants via haustoria capable of drawing nutrients from host vascular tissue. The connection of the haustorium to the host marks a shift in parasite metabolism from autotrophy to at ...
Clermont, Kristen, Collakova, Eva, dePamphilis, Claude W, Liu, Siming, Wang, Yaxin, Westwood, James H, Yang, Zhenzhen, Yoder, John I   +7 more
core   +2 more sources

Theoretical results for chemotactic response and drift of E. coli in a weak attractant gradient [PDF]

J. Theor. Biol. 266(1), 99-106 (2010), 2010
The bacterium Escherichia coli (E. coli) moves in its natural environment in a series of straight runs, interrupted by tumbles which cause change of direction. It performs chemotaxis towards chemo-attractants by extending the duration of runs in the direction of the source.
arxiv  

Clinical prediction system of complications among COVID-19 patients: a development and validation retrospective multicentre study [PDF]

arXiv, 2020
Existing prognostic tools mainly focus on predicting the risk of mortality among patients with coronavirus disease 2019. However, clinical evidence suggests that COVID-19 can result in non-mortal complications that affect patient prognosis. To support patient risk stratification, we aimed to develop a prognostic system that predicts complications ...
arxiv  

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source

Thyroid Dysfunction in Primary Biliary Cholangitis: A Comparative Study at Two European Centers [PDF]

, 2017
open10siOBJECTIVES: Primary biliary cholangitis (PBC) is often associated with other autoimmune diseases, but little is known about the influence of thyroid disease (TD) on the natural history of PBC.

core   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Slow but complete, two state unfolding/refolding of lysozyme in "tuned" ~6M guanidinium carboxylate solutions [PDF]

arXiv, 2011
We using differential scanning calorimetry of the unfolding process to identify conditions in which the pseudo two-state refolding of thermally denatured lysozyme can be observed to occur on time scales of hours, in solutions that approach 6M in guanidinium cation, Gdm+. Remarkably, the fraction of lysozyme re-folded at 25 C reaches, and remains at 1.0.
arxiv  

Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis B-related fibrosis: a leading meta-analysis

BMC Gastroenterology, 2012
BackgroundThe aspartate aminotransferase-to-platelet ratio index (APRI), a tool with limited expense and widespread availability, is a promising noninvasive alternative to liver biopsy for detecting hepatic fibrosis.
Wen-wen Jin, Zhong-Hua Lin, Y. Xin, Xiangjun Jiang, Quanjiang Dong, S. Xuan   +5 more
semanticscholar   +1 more source