Results 91 to 100 of about 472,544 (350)

Hepatitis C virus genotypes in liver transplant recipients: Impact on posttransplant recurrence, infections, response to interferon-α therapy and outcome [PDF]

, 1997
Background. End-stage liver disease due to hepatitis C virus (HCV) is the most common indication for liver transplantation in U.S. veterans. We investigated the influence of HCV genotypes on the incidence and timing of recurrent HCV hepatitis, survival ...
Fung, JJ, Gayowski, T, Laskus, T, Marino, IR, Morelli, F, Rakela, J, Singh, N, Starzl, TE, Vargas, H, Wagener, M, Wannstedt, C   +10 more
core   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Pengaruh Penambahan Tepung Daun Kelor (Moringa oleifera) pada Pakan Tikus Putih Terhadap Aktivitas Enzim Alanin Aminotransferase dan Aspartate Aminotransferase

Indonesia Medicus Veterinus, 2018
Penelitian ini menggunakan 25 ekor tikus putih betina, masing-masing kelompok terdiri atas lima ekor tikus putih betina P0 (hewan coba diberikan pakan tanpa penambahan tepung daun kelor), P1 (pakan di tambahkan tepung daun kelor 2,5 %) P2 (pakan di ...
Asri Setiyowati, Iwan Harjono Utama, Ni Luh Eka Setiasih   +2 more
doaj  

Eating quickly is associated with a low aspartate aminotransferase to alanine aminotransferase ratio in middle-aged adults: a large-scale cross-sectional survey in Japan

Archives of Public Health, 2020
Background An elevated alanine aminotransferase (ALT) and a low aspartate aminotransferase (AST) to ALT ratio (AST/ALT ratio) suggest nonalcoholic fatty liver disease and nonalcoholic steatohepatitis, increasing the risk of liver cirrhosis and ...
Eri Ozaki, Hirotaka Ochiai, Takako Shirasawa, Takahiko Yoshimoto, Satsue Nagahama, Jun Muramatsu, Takahiko Chono, Takayoshi Ito, Haruhiro Inoue, Akatsuki Kokaze   +9 more
doaj   +1 more source

CRYPTOGENIC INCREASED ACTIVITY OF ASPARTATE AMINOTRANSFERASE: A CASE REPORT

Slovenska pediatrija, 2021
We present a case of cryptogenic elevation of aspartate aminotransferase (AST) activity. AST is an enzyme found in many tissues, so the serum activity of this enzyme may be elevated in various diseases.
Tjaša Žagar, Rok Orel
doaj   +1 more source

Reactivation of hepatitis B virus with immune-escape mutations after ocrelizumab treatment for multiple sclerosis [PDF]

, 2019
Ocrelizumab is an anti-CD20 monoclonal antibody for the treatment of multiple sclerosis (MS) that is closely related to rituximab. We describe a case of hepatitis B virus (HBV) reactivation in an MS patient with resolved HBV infection receiving ...
Altieri, Marta, Annecca, Rosanna, Aragri, Marianna, Ciardi, Maria R, Iannetta, Marco, Mastroianni, Claudio M, Pontecorvo, Simona, Russo, Gianluca, Salpini, Romina, Svicher, Valentina, Vullo, Vincenzo, Zingaropoli, Maria A   +11 more
core   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Liver functions and medication adherence in tuberculosis patients after 6 months of antituberculosis treatment in Indonesia

Journal of International Medical Research
Objective The objective of this study was to assess liver functions in tuberculosis patients after 6 months of treatment and determine the difference in the level of liver enzymes based on medication adherence and patient characteristics. Methods We used
Dyah Aryani Perwitasari, Triantoro Safaria, Didik Setiawan, Haafizah Dania, Salma Auliya Fatimah, Imaniar Noor Faridah   +5 more
doaj   +1 more source

Plasmids in the aphid endosymbiont Buchnera aphidicola with the smallest genomes. A puzzling evolutionary story.

, 2006
Buchnera aphidicola, the primary endosymbiont of aphids, has undergone important genomic and biochemical changes as an adaptation to intracellular life.
Gil, Rosario, Latorre, Amparo, Perez-Brocal, Vicente, Sabater-Muñoz, Beatriz, Silva, Francisco J   +4 more
core   +1 more source