Results 141 to 150 of about 240,598 (262)

Self‐Propelled In Situ Polymerized Nanoparticles Activating the STING Pathway for Enhanced Bladder Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐propelled nanomedicine delivery system forms DMCU nanoparticles in the bladder via in situ polymerization of dopamine hydrochloride, Mn2+, cGAMP, and urease. The urease‐driven propulsion enhances retention and drug delivery. These nanoparticles activate the STING pathway, stimulating dendritic cells and T cells to boost anti‐bladder cancer ...
Lei Peng, Anguo Zhao, Rongkang Li, Yujun Liu, Daitian Tang, Dashi Deng, Qi Zhuang, Rui Liang, Shaohua Zhang, Song Wu   +9 more
wiley   +1 more source

The primary structure of aspartate aminotransferase from pig heart muscle. Partial sequences determined by digestion with pepsin and trypsin [PDF]

, 1972
Shawn Doonan, Hilary J. Doonan, Francesca Riva, C. A. Vernon, John M. Walker, Francesco Bossa, Donatella Barra, Manuel Carloni, P. Fasella   +8 more
openalex   +1 more source

In Situ Assembly of Fluorogenic RNA for Screening Natural Anti‐Liver Fibrosis Products via Dynamic Visualization of COL1A1 mRNA

Advanced Science, EarlyView.
This study introduces an in situ assembly of fluorogenic RNA approach for screening natural anti‐liver fibrosis compounds and dynamic visualization of endogenous COL1A1 mRNA in live cells. It offers a simple, cost‐effective approach of visualizing RNA dynamics and conducting drug screening in live cells, presenting a significant potential for the ...
Rui Bai, Li‐Zeng Zhu, Changfa Shao, Zheng Yin, Qun Liu, Yu Gu, Bin Liu   +6 more
wiley   +1 more source

Kinetics of the Inhibition of Aspartate Aminotransferase Isozymes by dl‐Glyceraldehyde 3‐Phosphate [PDF]

, 1971
Levy Kopelovich, Lawrence Sweetman, Jerome S. Nisselbaum   +2 more
openalex   +1 more source

Nucleic Acid‐Locked Smart Carrier for Photothermal/Chemotherapy‐Amplified Immunogenic Cell Death to Enhance Systemic Antitumor Efficacy

Advanced Science, EarlyView.
Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang, Tianyu Gai, Jiwei Wang, Yucai Wu, Si‐Ming Zeng, Dongyuan Zhao, Wei Li   +6 more
wiley   +1 more source

GENETIC ANALYSIS OF ASPARTATE AMINOTRANSFERASE ISOZYMES FROM HYBRIDS BETWEEN DROSOPHILA MELANOGASTER AND DROSOPHILA SIMULANS AND MUTAGEN-INDUCED ISOZYME VARIANTS [PDF]

, 1976
E. H. Grell
openalex   +1 more source

New pediatric percentiles of liver enzyme serum levels (alanine aminotransferase, aspartate aminotransferase, γ‐glutamyltransferase): Effects of age, sex, body mass index, and pubertal stage

Hepatology, 2018
Sarah Bussler, M. Vogel, Diana Pietzner, Kristian Harms, Theresa Buzek, Melanie Penke, N. Händel, A. Körner, U. Baumann, W. Kiess, G. Flemming   +10 more
semanticscholar   +1 more source

Customized Hydrogel System for the Spatiotemporal Sequential Treatment of Periodontitis Propelled by ZEB1

Advanced Science, EarlyView.
Through elaborate design, a biodegradable scaffold with excellent mechanical properties and suitability is fabricated, providing spatial support for subsequent physiological activities. The prepared GA‐HBC‐LIC hydrogel possesses sequential antibacterial, antioxidant, anti‐inflammatory and immunomodulatory functions, offering a suitable chemical and ...
Jiafei Chen, Xiaoxu Guan, Lina Chen, Bingzhu Zheng, Feiyu Li, Chao Fang, Yike Fu, Xiang Li, Huiming Wang, Yi Zhou   +9 more
wiley   +1 more source

Phosphorylation of threonine residue in apo-aspartate aminotransferase during the inhibition with N-(pyridoxyl-5′-phosphate)-L-glutamic acid

, 1969
R. M. Khomutov, Severin Se, Elena N. Khurs, N.N. Gulyaev   +3 more
openalex   +1 more source

Alanine aminotransferase and aspartate aminotransferase measurements with two automated analyzers, SMAC and the ABA-100, compared. [PDF]

, 1979
G V Purcell, D B Behenna, P R Walsh
openalex   +1 more source