Results 141 to 150 of about 189,959 (292)

Comparison of Some Kinetic Properties of Cytoplasmic and Mitochondrial Aspartate Aminotransferases in Holstein Steer Liver [PDF]

, 1989
Megumi Yamada, Manabu Tanaka
openalex   +1 more source

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

Advanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He, Haoyu Wang, Zizhen Yang, Hui Li, Bei Liu, Kaiwei Chen, Zhinan Wu, Xinnan Zhao, Hewei Liang, Mengmeng Wang, Xiaofang Li, Yiyi Zhong, Haifeng Zhang, Liang Xiao, Karsten Kristiansen, Jixing Peng, Yuanqiang Zou, Shangyong Li   +17 more
wiley   +1 more source

Association between alanine aminotransferase-to-aspartate aminotransferase ratio and obstructive sleep apnea: A cross-sectional study of NHANES. [PDF]

Medicine (Baltimore)
Zheng Y, Zheng Y, Xu H.
europepmc   +1 more source

Purification, crystallization and preliminary X-ray analysis of the aspartate aminotransferase ofPlasmodium falciparum [PDF]

, 2010
Rishabh Jain, Rositsa Jordanova, Ingrid Müller, Carsten Wrenger, Matthew R. Groves   +4 more
openalex   +1 more source

Aspartate Aminotransferase, Cytoplasmic [PDF]

, 2020
openaire   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Aspartate aminotransferase-to-platelet ratio index (APRI) for staging of fibrosis in adults with chronic hepatitis C. [PDF]

Cochrane Database Syst Rev
Dreytser E, Blyuss O, Mudrova A, Turankova T, Gurusamy KS, Pavlov CS.   +5 more
europepmc   +1 more source

F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway

Advanced Science, EarlyView.
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling   +16 more
wiley   +1 more source

Correlation of aspartate aminotransferase/platelet ratio index with hepatic venous pressure gradient in cirrhosis [PDF]

, 2014
Vipin Verma, Shiv Kumar Sarin, Praveen Sharma, Ashish Kumar   +3 more
openalex   +1 more source

Ambulatory end-stage liver disease in Ghana; patient profile and utility of alpha fetoprotein and aspartate aminotransferase - platelet ratio index. [PDF]

, 2020
Yvonne Ayerki Nartey, Yaw Asante Awuku, Adwoa Agyei‐Nkansah, Amoako Duah, Sally Afuah Bampoh, Joshua Ayawin, Shadrack Osei Asibey, Niklas K. Björkström, Weimin Ye, Mary Afihene, Lewis R. Roberts, Amelie Plymoth   +11 more
openalex   +1 more source