Results 151 to 160 of about 472,544 (350)

The Study of 201TlCl Short-Term Effects on Rat Serum Factors [PDF]

open access: yesمجله علوم و فنون هسته‌ای, 2011
Tl-201 administration for cardial scan using SPECT has been performed for more than 4 decades, while in Iran it has been produced and used for 17 years.
A.R Jalilian, M Alinejad
doaj  

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

Clinical guidelines for the management of cutaneous leishmaniasis in British military personnel. [PDF]

open access: yes, 2005
Bailey, MS   +7 more
core   +1 more source

The prevalence of the elevation serum alanine amino transaminase at gorgan in Northern Iran [PDF]

open access: yes, 2011
The elevation of serum alanine aminotranferase levels is associated most commonly with some forms of liver diseases. The aim of this study was to determine the prevalence of elevated serum alanine aminotransferase levels and the possible liver damages in
Mansourian, A.R.   +2 more
core  

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

open access: yesAdvanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi   +15 more
wiley   +1 more source

Laminin Levels as a Biomarker for Liver injury in Methamphetamine Addict

open access: yesمجلة كلية الطب
Background: Methamphetamine (METH) is a potent synthetic stimulant that significantly impacts the central nervous system and can lead to severe liver damage.
Halla Gh. Mahmood, Shahbaa W. Sami
doaj   +1 more source

Interactions between Cystathionase and Aspartate Aminotransferase

open access: yesJournal of Biological Chemistry, 1972
The interaction of cystathionase with the apoprotein of the enzyme aspartate aminotransferase induces, concomitant with inhibition of cystathionase activity, an increase in aminotransferase activity. The interaction between both proteins brings about a change in the amplitude of the circular dichroic band corresponding to pyridoxal-5-P bound to the ...
openaire   +2 more sources

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

open access: yesAdvanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang   +23 more
wiley   +1 more source

Species Dependent Toxicity Comparison Outcome

open access: yesAdvanced Science, EarlyView.
By quantitatively assessing and comparing toxicity responses across different animal species and material compositions, our data reveal that toxicity rankings among different materials may be reversed across species. ABSTRACT Toxicity comparison plays a crucial role in material selection across diverse application fields.
Lian Xiao   +7 more
wiley   +1 more source

Sex Hormone-Binding Globulin Levels Are Inversely Associated With Nonalcoholic Fatty Liver Disease in HIV-Infected and -Uninfected Men. [PDF]

open access: yes, 2019
BackgroundNonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease worldwide. Elevated sex hormone-binding globulin (SHBG) levels have been observed in the setting of HIV and may protect against some metabolic disorders.
Brown, Todd T   +10 more
core  

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