Results 181 to 190 of about 200,089 (263)

Theranostic nanoplatform for high‐performance dual‐modal magnetic resonance imaging‐guided therapy of orthotopic hepatocellular carcinoma

open access: yesBMEMat, EarlyView.
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin   +7 more
wiley   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

open access: yesBMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu   +13 more
wiley   +1 more source

A novel biomimetic liposome drug delivery system mediated by macrophage targeting for precision treatment of encephalitis

open access: yesBMEMat, EarlyView.
An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu   +5 more
wiley   +1 more source

An Increase in Aspartate Aminotransferase Can Predict Worsening Disease Severity in Japanese Patients with COVID-19. [PDF]

open access: yesClin Pract
Matsumoto K   +9 more
europepmc   +1 more source

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

open access: yesBMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li   +9 more
wiley   +1 more source

Presence of Aspartate Aminotransferase in Peri-Implant Crevicular Fluid with and without Mucositis.

open access: yesJ Pharm Bioallied Sci
Devadiya P   +6 more
europepmc   +1 more source

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