Results 21 to 30 of about 240,598 (262)

Clinical characteristics of antimitochondrial antibody-positive patients at a safety net health care system in Arizona. [PDF]

, 2017
Background and aimsTo assess whether aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (AP) levels can predict the diagnosis of primary biliary cholangitis (PBC) or any other diagnoses and whether PBC occurs either
Ayutyanont, Napatkamon, Bhattarai, Bikash, Gish, Robert, Jayaram, Lakshmi, Movahedi, Zohreh, Nadir, Abdul, Tan, Susanna   +6 more
core   +1 more source

Phosphoenolpyruvate Carboxykinase Is Involved in the Decarboxylation of Aspartate in the Bundle Sheath of Maize [PDF]

, 1999
We recently showed that maize (Zea mays L.) leaves contain appreciable amounts of phosphoenolpyruvate carboxykinase (PEPCK; R.P. Walker, R.M. Acheson, L.I. Técsi, R.C. Leegood [1997] Aust J Plant Physiol 24: 459–468).
Chen, Z., Leegood, R.C., Walker, R.P., Wingler, A.   +3 more
core   +2 more sources

Isolated elevation of aspartate aminotransferase (AST) in an asymptomatic patient due to macro‐AST

Journal of clinical laboratory analysis (Print), 2018
A rare and benign cause of isolated aspartate aminotransferase (AST) increase is due to the presence of macro aspartate aminotransferase (macro‐AST). Macro‐AST is not usually considered by clinicians, leading to a large number of unnecessary and even ...
Arturo González Raya, Ramón Coca Zúñiga, Eva Martín Salido   +2 more
semanticscholar   +1 more source

Glutamine-Glutamate Cycle Flux Is Similar in Cultured Astrocytes and Brain and Both Glutamate Production and Oxidation Are Mainly Catalyzed by Aspartate Aminotransferase

Biology, 2017
The glutamine-glutamate cycle provides neurons with astrocyte-generated glutamate/γ-aminobutyric acid (GABA) and oxidizes glutamate in astrocytes, and it returns released transmitter glutamate/GABA to neurons after astrocytic uptake.
L. Hertz, D. Rothman
semanticscholar   +1 more source

A Biochemical Logic Approach to Biomarker-Activated Drug Release [PDF]

J. Mater. Chem. 22, 19709-19717 (2012), 2013
The present study aims at integrating drug-releasing materials with signal-processing biocomputing systems. Enzymes alanine transaminase (ALT) and aspartate transaminase (AST)---biomarkers for liver injury---were logically processed by a biocatalytic cascade realizing Boolean AND gate. Citrate produced in the system was used to trigger a drug-mimicking
arxiv   +1 more source

Coupling enhanced sampling of the apo-receptor with template-based ligand conformers selection: Performance in pose prediction in the D3R-GC4 [PDF]

Journal of Computer-Aided Molecular Design 34, 149-162 (2020), 2020
We report the performance of our newly introduced Ensemble Docking with Enhanced sampling of pocket Shape (EDES) protocol coupled to a template-based algorithm to generate near-native ligand conformations in the 2019 iteration of the Grand Challenge organized by the D3R consortium.
arxiv   +1 more source

Association of the Aspartate Aminotransferase to Alanine Aminotransferase Ratio with BNP Level and Cardiovascular Mortality in the General Population: The Yamagata Study 10-Year Follow-Up

Disease Markers, 2016
Background. Early identification of high risk subjects for cardiovascular disease in health check-up is still unmet medical need. Cardiovascular disease is characterized by the superior increase in aspartate aminotransferase (AST) to alanine ...
Miyuki Yokoyama, Tetsu Watanabe, Y. Otaki, Hiroki Takahashi, T. Arimoto, T. Shishido, T. Miyamoto, T. Konta, Y. Shibata, M. Daimon, Y. Ueno, T. Kato, T. Kayama, I. Kubota   +13 more
semanticscholar   +1 more source

Lighter serum copper isotopic composition in patients with early non-alcoholic fatty liver disease [PDF]

, 2020
Objective The occurrence of non-alcoholic fatty liver disease (NAFLD) is globally increasing. To challenge the current incidence of NAFLD, non-invasive markers that could identify patients at risk or monitor disease progression are an important need ...
Costas Rodriguez, Marta, Devisscher, Lindsey, Hastuti, Agustina Ari Murti Budi, Lefere, Sander, Van Campenhout, Sanne, Van Vlierberghe, Hans, Vanhaecke, Frank   +6 more
core   +1 more source

Energetics of ion competition in the DEKA selectivity filter of neuronal sodium channels [PDF]

Condens. Matter Phys., 2015, vol. 18, No. 1, 13601, 2015
The energetics of ionic selectivity in the neuronal sodium channels is studied. A simple model constructed for the selectivity filter of the channel is used. The selectivity filter of this channel type contains aspartate (D), glutamate (E), lysine (K), and alanine (A) residues (the DEKA locus).
arxiv   +1 more source

Serum alanine aminotransferase/aspartate aminotransferase ratio is one of the best markers of insulin resistance in the Chinese population

Nutrition and Metabolism, 2017
BackgroundThe alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio is reportedly associated with insulin resistance (IR). However, few studies have explored the relationship between the ALT/AST ratio and IR in the Chinese population ...
Li Zhao, Jing Cheng, Yingchao Chen, Qin Li, B. Han, Yi Chen, F. Xia, Chi Chen, D. Lin, Xuemei Yu, Ningjian Wang, Yingli Lu   +11 more
semanticscholar   +1 more source