Diminishing Use of Liver Biopsy among Liver Transplant Recipients for Hepatitis C. [PDF]
Background and Aims: Hepatitis C virus (HCV) cirrhosis is the leading indication for liver transplantation in the United States and recurrent HCV following liver transplantation is a major cause of allograft loss and mortality.
Aby, Elizabeth +6 more
core +1 more source
The aspartate aminotransferase-to-platelet ratio index has been reported to predict prognosis of patients with hepatocellular carcinoma. This study examined the prognostic potential of stratified aspartate aminotransferase-to-platelet ratio index for ...
Hao-Jie Yang +12 more
doaj +1 more source
Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial [PDF]
Background: Rucaparib, a poly(ADP-ribose) polymerase inhibitor, has anticancer activity in recurrent ovarian carcinoma harbouring a BRCA mutation or high percentage of genome-wide loss of heterozygosity.
Aghajanian, C +116 more
core +1 more source
Assessing Non-Invasive Liver Function in Patients With Intestinal Failure Receiving Total Parenteral Nutrition-Results From the Prospective PNLiver Trial [PDF]
Liver abnormalities in intestinal failure (IF) patients receiving parenteral nutrition (PN) can progress undetected by standard laboratory tests to intestinal failure associated liver disease (IFALD). The aim of this longitudinal study is to evaluate the
Bednarsch, Jan +10 more
core +1 more source
Correlation of biochemical profile at admission with severity and outcome of COVID-19
Background COVID-19 was detected in China in December 2019. The rapid dissemination and novelty of the disease resulted in an epidemic. This study aimed to identify biochemical parameters at admission that can be used to categorize severity and outcome ...
Abdullah Sadiq +6 more
doaj +1 more source
Background. Early identification of high risk subjects for cardiovascular disease in health check-up is still unmet medical need. Cardiovascular disease is characterized by the superior increase in aspartate aminotransferase (AST) to alanine ...
Miyuki Yokoyama +13 more
semanticscholar +1 more source
Effect of Orthodontic Tooth Movement on Salivary Aspartate Aminotransferase Activity
Aspartate aminotransferase is one of biological indicator in gingival crevicular fluid (CGF). Force orthodontic application could increase activity of aspartate aminotransferase in CGF.
Steiven Adhitya +3 more
doaj +1 more source
Use of saliva aspartate aminotransferase in diagnosing periodontal disease
Background and Aims: Periodontal disease is one of the common inflammatory diseases. Several enzymes in saliva and gingival crevicular fluid are evaluated for early diagnosis of periodontal disease.
Harshada Shinde +2 more
doaj +1 more source
A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia. [PDF]
Acute myeloid leukemia (AML) cells meet the higher energy, metabolic, and signaling demands of the cell by increasing mitochondrial biogenesis and mitochondrial protein translation.
Brandwein, Joseph +14 more
core +1 more source
An increased aspartate aminotransferase-to-alanine aminotransferase ratio (AAR) has been widely used as a marker of advanced hepatic fibrosis. Increased AAR was also shown to be significantly associated with the risk of developing cardiovascular (CV ...
G. Zoppini +6 more
semanticscholar +1 more source

