Results 41 to 50 of about 414,727 (380)

Should patients with abnormal liver function tests in primary care be tested for chronic viral hepatitis: cost minimisation analysis based on a comprehensively tested cohort [PDF]

, 2011
Background Liver function tests (LFTs) are ordered in large numbers in primary care, and the Birmingham and Lambeth Liver Evaluation Testing Strategies (BALLETS) study was set up to assess their usefulness in patients with no pre-existing or self ...
AA Butt, Alan J Girling, B Weber, C Trepo, CS Wang, D Lavanchy, David T Arnold, DJ McLernon, DR Dufour, DS Pratt, DW Hutton, E Castelnuovo, E Tanaka, E Yano, EG Giannini, F Kanwal, FJ de Serres, GA Poland, GJ Dore, GM Pendino, HC Kim, IK Veldhuijzen, J Nakamura, J Thompson Coon, JK Limdi, JV Metcalf, K Stein, K Witte, KJ Petrie, KM Kim, L Olivarez, Louise M Bentham, M Persico, M Weinstein, M Worwood, MW Whitehead, P Sherwood, PM Todd, PT Donnan, R D'Souza, R Hultcrantz, R Jamali, RG Newcombe, Richard J Lilford, RM Theal, Ruth P Jacob, S Bellentani, S Daniel, SN Lu, UL Mathiesen, World Health Organization, World Health Organization, World Health Organization, Geneva   +52 more
core   +3 more sources

Stratified aspartate aminotransferase-to-platelet ratio index accurately predicts survival in hepatocellular carcinoma patients undergoing curative liver resection

Tumor Biology, 2017
The aspartate aminotransferase-to-platelet ratio index has been reported to predict prognosis of patients with hepatocellular carcinoma. This study examined the prognostic potential of stratified aspartate aminotransferase-to-platelet ratio index for ...
Hao-Jie Yang, Jing-Hang Jiang, Yu-Ting Yang, Zhe Guo, Ji-jia Li, Xuan-han Liu, Fei Lu, Feng-Hua Zeng, Jin-Song Ye, Ke-Lan Zhang, Neng-Zhi Chen, Bang-De Xiang, Le-Qun Li   +12 more
doaj   +1 more source

Isolated elevation of aspartate aminotransferase (AST) in an asymptomatic patient due to macro‐AST

Journal of clinical laboratory analysis (Print), 2018
A rare and benign cause of isolated aspartate aminotransferase (AST) increase is due to the presence of macro aspartate aminotransferase (macro‐AST). Macro‐AST is not usually considered by clinicians, leading to a large number of unnecessary and even ...
Arturo González Raya, Ramón Coca Zúñiga, Eva Martín Salido   +2 more
semanticscholar   +1 more source

Glutamine-Glutamate Cycle Flux Is Similar in Cultured Astrocytes and Brain and Both Glutamate Production and Oxidation Are Mainly Catalyzed by Aspartate Aminotransferase

Biology, 2017
The glutamine-glutamate cycle provides neurons with astrocyte-generated glutamate/γ-aminobutyric acid (GABA) and oxidizes glutamate in astrocytes, and it returns released transmitter glutamate/GABA to neurons after astrocytic uptake.
L. Hertz, D. Rothman
semanticscholar   +1 more source

Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium. [PDF]

, 2019
ObjectivePopulations of Mexican American ancestry are at an increased risk for nonalcoholic fatty liver disease. The objective of this study was to determine whether loci in known and novel genes were associated with variation in aspartate ...
Chen, Yii-Der I, Fingerlin, Tasha E, Goodarzi, Mark O, Guo, Xiuqing, Langefeld, Carl D, Norris, Jill M, Palmer, Nicholette D, Raffel, Leslie J, Rotter, Jerome I, Taylor, Kent D, Wagenknecht, Lynne E, Wang, Nan, Watanabe, Richard M, Williams, Adrienne H, Xiang, Anny H, Young, Kendra A   +15 more
core   +2 more sources

The association of aspartate transaminase-to-alanine transaminase ratio and metabolic syndrome among HIV patients in Sidama Region, South Ethiopia

SAGE Open Medicine, 2023
Objective: Studies on the association of the aspartate transaminase-to-alanine transaminase ratio with the metabolic syndrome and its components among HIV patients were scarce.
Wondwossen Abera, Temesgen Bizuayehu Wube, Tsegaye Alemayehu   +2 more
doaj   +1 more source

Association of the Aspartate Aminotransferase to Alanine Aminotransferase Ratio with BNP Level and Cardiovascular Mortality in the General Population: The Yamagata Study 10-Year Follow-Up

Disease Markers, 2016
Background. Early identification of high risk subjects for cardiovascular disease in health check-up is still unmet medical need. Cardiovascular disease is characterized by the superior increase in aspartate aminotransferase (AST) to alanine ...
Miyuki Yokoyama, Tetsu Watanabe, Y. Otaki, Hiroki Takahashi, T. Arimoto, T. Shishido, T. Miyamoto, T. Konta, Y. Shibata, M. Daimon, Y. Ueno, T. Kato, T. Kayama, I. Kubota   +13 more
semanticscholar   +1 more source

Relationship between the Serum De Ritis Ratio and Diabetes Tests in Korean Adults Who Underwent Health Screening at a General Hospital in Gyeonggi-do

Korean Journal of Clinical Laboratory Science, 2023
The purpose of this study was to analyze the relationship between diabetes and liver function test results. Unlike type 2 diabetes mellitus (T2DM), hepatogenous diabetes is caused by abnormal liver function.
Hyun Ho SUNG, Ho-Keun CHOI
doaj   +1 more source

Serum alanine aminotransferase/aspartate aminotransferase ratio is one of the best markers of insulin resistance in the Chinese population

Nutrition and Metabolism, 2017
BackgroundThe alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio is reportedly associated with insulin resistance (IR). However, few studies have explored the relationship between the ALT/AST ratio and IR in the Chinese population ...
Li Zhao, Jing Cheng, Yingchao Chen, Qin Li, B. Han, Yi Chen, F. Xia, Chi Chen, D. Lin, Xuemei Yu, Ningjian Wang, Yingli Lu   +11 more
semanticscholar   +1 more source

Effects of Potassium Iodide on Aspartate Aminotransferase [PDF]

European Journal of Biochemistry, 1974
The absorption spectrum of the phosphopyridoxal form of the enzyme, aspartate aminotransferase, can be perturbed by the anion iodide over a wide range of pH values.The binding of this anion to the catalytic site of the enzyme brings about a decrease in the absorption at 360 nm and a concomitant increase in the absorption band centered at 430 nm ...
Jorge E. Churchich, Noranna Burridge
openaire   +3 more sources