Results 151 to 160 of about 181,665 (333)

SF3A3 Drives Tumorigenesis in Endometrial Cancer by Enhancing c‐FOS Expression and Represents a Potential Therapeutic Target

Advanced Science, EarlyView.
The role of splicing factor 3A subunit 3 (SF3A3) in driving endometrial cancer (EC) progression and potential therapeutic interventions. SF3A3, a core component of the U2 small nuclear ribonucleoprotein (U2 snRNP), is upregulated in endometrial cancer (EC) and promotes tumor growth and cisplatin resistance. RNA‐binding protein immunoprecipitation (RIP)
Wei Yu, Yi Gu, Hengrui Zhang, Wunan Huang, Lei Sun, Liangjian Ma, Xiaolei Liang, Lexin Liu, Guiping Chen, Weihua Wang, Zhongkai Cao, Xue Li, Xiangjun Chen, Lidan Hu   +13 more
wiley   +1 more source

Salivary and Serum Aspartate Aminotransferases and Alanine Aminotransferases in Insulin-Dependent Diabetes Mellitus and Normal Children: A Comparative Study.

J Int Soc Prev Community Dent, 2018
Vinod KS, Madathil LP, Shetty P, Kaur H, Patel M, Gouraha A.   +5 more
europepmc   +1 more source

Interaction of AMP with cytosolic apo‐aspartate aminotransferase [PDF]

, 1983
Alberto Di Donato, Riccardo Di Fiore, Anna Maria Vittoria Garzillo, Gennaro Marino   +3 more
openalex   +1 more source

Nanosensitizer for Cancer Radioimmunotherapy via Anti‐IL‐35 Blockade Boosted Innate Immunity Activation

Advanced Science, EarlyView.
Zheng et al. designed a tumor microenvironment (TME)‐responsive nanosystem, HmBMH@MSA‐2. It targets tumors, releases MSA‐2 and Mn ions in high glutathione (GSH) conditions, achieving STING agonist delivery and MRI. The nanosystem promotes chemodynamic therapy (CDT), achieves radiosensitization, and activates the cGAS‐STING pathway.
Yinfei Zheng, Shuting Zheng, Yushu Liao, Zede Wu, Chenxi He, Qiuyu Li, Honglei Hu, Zheyu Shen, Yikai Xu, Chenggong Yan, Bingxia Zhao, Meirong Hou   +11 more
wiley   +1 more source

Drug induced liver injury in HIV patients on dolutegravir based antiretroviral therapy regimens in Wolaita Sodo comprehensive specialized hospital. [PDF]

Sci Rep
Abraham F, Toma A, Balcha T, Tigabu BM.
europepmc   +1 more source

Time-dependent Inhibition of Aspartate Aminotransferase Isozymes by dl-Glyceraldehyde 3-Phosphate

, 1970
Levy Kopelovich, Lawrence Sweetman, Jerome S. Nisselbaum   +2 more
openalex   +1 more source

The Proportion of Mitochondrial Isoenzyme of Aspartate Aminotransferase Is Not Elevated in Reye's Syndrome [PDF]

, 1983
Donald M. Mock, Marion O. Scott, Nell I. Mock, Michael Thaler   +3 more
openalex   +1 more source

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

Advanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen   +7 more
wiley   +1 more source

Cytoplasmic Aspartate Aminotransferase: Syncatalytic Sulfhydryl Group Modification

, 1973
Walter Birchmeier, Kenneth J. Wilson, Philipp Christen   +2 more
openalex   +1 more source

Pyroptosis‐Inducing Platinum(IV) Prodrugs via GSDME Pathway for Chemoimmunotherapy and Metastasis Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Three PtIV prodrugs MRP, DRP, and HRP are designed to induce pyroptosis in low GSDME‐expressing tumor cells via the Caspase‐3/GSDME pathway. By relaxing chromatin and reactivating GSDME, HRP can effectively induce pyroptosis, enhance pro‐inflammatory cytokine production, and exhibit potent antitumor effects.
Xinda Yang, Chuansheng Xu, Youliang Zeng, Chunhui Wang, Yan Gao, Jie Ding, Sirui Chen, Yuheng Pan, Xin Zhang, Zongwan Mao, Shuo Shi   +10 more
wiley   +1 more source