Managing Aminotransferase Elevations in Patients with Friedreich Ataxia Treated with Omaveloxolone: A Review and Expert Opinion on Use Considerations. [PDF]
Perlman S+4 more
europepmc +1 more source
Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu+14 more
wiley +1 more source
TK2268 encodes the major aminotransferase involved in the conversion from oxaloacetic acid to aspartic acid in <i>Thermococcus kodakarensis</i>. [PDF]
Su Y+5 more
europepmc +1 more source
YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis
This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li+8 more
wiley +1 more source
Achillea millefolium capsule improved liver enzymes and lipid profile compared to placebo in patients with type 2 diabetes: a double-blind randomized clinical trial. [PDF]
Daneshvar-Ghahfarokhi S+4 more
europepmc +1 more source
Heparin interferes with aspartate aminotransferase activity determination in the Ektachem 700. [PDF]
J D Berg+3 more
openalex +1 more source
Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang+9 more
wiley +1 more source
Silent Threats to the Liver: Acute Hepatotoxicity Attributed to Selective Androgen Receptor Modulators (SARMs). [PDF]
Habeb B, Valdes O, Khair S, Thomson ES.
europepmc +1 more source