Aspartate Residues Far from the Active Site Drive O-GlcNAc Transferase Substrate Selection
O-GlcNAc is an abundant post-translational modification found on nuclear and cytoplasmic proteins in all metazoans. This modification regulates a wide variety of cellular processes, and elevated O-GlcNAc levels have been implicated in cancer progression.
Cassandra M. Joiner +4 more
openaire +5 more sources
Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer [PDF]
<b>Aim</b>: To comprehensively compare the prognostic value of tumour and patient-related factors in patients undergoing curative surgery for colon cancer.
Benson +41 more
core +1 more source
A 57 year old man with chronic renal failure and cardiac tamponade who developed ischemic hepatitis
Ischemic hepatitis is an infrequent entity, usually associated with low cardiac out put. We present a case of a 57 year-old man with chronic renal failure and cardiac tamponade who developed elevation of serum alanine transferase level of 5,054 U/L ...
Eric López-Méndez +7 more
doaj +1 more source
Effects of Chronic Kidney Disease on Liver Enzymes Activity During Pre and Post Hemodialysis
Background: Worldwide chronic kidney disease is one of the primary public health problems. This study aimed to find the activity of liver enzymes alanine aminotransferase, aspartate transaminase, alkaline phosphatase, and Gamma-glutamyl transferase in ...
Sanjay Kumar Jha +2 more
doaj +1 more source
EFFECT OF COLD AQUEOUS EXTRACT OF FICUS CARCIA LEAVES ON SOME BIOCHEMICAL PARAMETERS OF BLOOD AND TISSUES IN RATS [PDF]
Different concentrations of cold aqueous extract Ficus carcia leaves were studied on the levels of glucose, cholesterol, triglycerides, total lipids, Aspartate amino transferase (AST) and Alanine amino transferase (ALT) activity and total protein in the ...
Sameira M. Al-Katib
doaj +1 more source
Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium. [PDF]
ObjectivePopulations of Mexican American ancestry are at an increased risk for nonalcoholic fatty liver disease. The objective of this study was to determine whether loci in known and novel genes were associated with variation in aspartate ...
Chen, Yii-Der I +15 more
core +2 more sources
Yale - Aspartate Amino Transferase v1 [PDF]
Summary: Procedure used to measure the activity of Aspartate Amino Transferase (AST). AST activity is measured by the enzymatically coupled reactions of AST (to form oxaloacetate from aspartate and α-ketoglutarate) and malate dehydrogenase (conversion of oxaloacetate to malate with oxdiation of NADH to NAD).
Gary Cline, John Stack
openaire +1 more source
Serum γ-glutamyltransferase, alanine aminotransferase and aspartate aminotransferase activity in healthy blood donor of different ethnic groups in Gorgan [PDF]
Introduction: Measure of liver enzymes may help to increase safety of blood donation for both blood donor and recipient. Determination of liver enzymes may prepare valuable clinical information.
Marjani, A. +2 more
core +1 more source
Allosteric Regulation Alters Carrier Domain Translocation in Pyruvate Carboxylase [PDF]
Pyruvate carboxylase (PC) catalyzes the ATP-dependent carboxylation of pyruvate to oxaloacetate. The reaction occurs in two separate catalytic domains, coupled by the long-range translocation of a biotinylated carrier domain (BCCP). Here, we use a series
Budelier, Melissa M. +3 more
core +3 more sources
The impact of aspartate transaminases (AST) and gamma-glutamyl transferase (GGT) in serum of deceased donors on outcomes after liver transplantation (LT) is unclear. This study aimed to explore the relationship between donor highest AST value or first donor GGT value and graft survival.
Rafaela Capelli +11 more
openaire +2 more sources

