Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source
Midgut proteome of an argasid tick, Ornithodoros erraticus: a comparison between unfed and engorged females [PDF]
16 páginas, 5 figuras y 2 tablas. -- Agradecimientos: Asistencia técnica de Rocío Vizcaíno Marín y María González Sánchez, del Instituto de Recursos Naturales y Agrobiología de Salamanca (IRNASA-CSIC) y de la Dra.
Oleaga, Ana +3 more
core +1 more source
Design, Synthesis and Biological Activity of Selective PHEX Inhibitors
Osteogenesis is a complex biological process that includes synthesis of an organic matrix composed mainly of type I collagen and mineralization of the organic matrix by deposition of hydroxyapatite crystals.
Elaref Ratemi, D. Gravel
semanticscholar +1 more source
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá +5 more
wiley +1 more source
Purification and characterization of microbial protease produced extracellularly from Bacillus subtilis FBL-1 [PDF]
An ammonium sulfate precipitation of fermentation broth produced by Bacillus subtilis FBL-1 resulted in 2.9-fold increase of specific protease activity.
Charalampopoulos, Dimitris +3 more
core +1 more source
N‐Truncated Superoxide Dismutase‐1 in Cerebrospinal Fluid Is Folded and Active
Superoxide dismutase 1 (SOD1) mutations cause amyotrophic lateral sclerosis (ALS) through mechanisms involving protein misfolding and aggregation. While C‐terminal truncations of SOD1 promote neurotoxicity, our study reveals that approximately one‐third of SOD1 in cerebrospinal fluid (CSF) is N‐terminally truncated—a striking observation given the ...
Laura Leykam +10 more
wiley +1 more source
Cloning, sequencing and extracellular expression of the alkaline protease gene from Bacillus stearothermophilus F1 [PDF]
The gene of a highly thermostable alkaline protease was amplified from Bacillus stearothermophilus F1 by polymerase chain reaction using consensus primers based on the sequences of serine protease genes from related species.
Fu, Zhibiao
core
Chemical Characterization, Antioxidant and Enzymatic Activity of Brines from Scandinavian Marinated Herring Products [PDF]
Brines generated during the last marination step in the production of marinated herring (Clupea harengus) were chemically characterized and analyzed for antioxidant and enzyme activities.
Baron, Caroline P. +4 more
core +1 more source
This guide proposes a roadmap combining state‐of‐the‐art computational and experimental approaches (including biophysical, biochemical, and imaging techniques) to identify, characterize, and contextualize extracellular matrix (ECM) protein interactions.
Leanna Leverton +4 more
wiley +1 more source
Structural modeling and functional analysis of the essential ribosomal processing protease Prp from Staphylococcus aureus [PDF]
In Firmicutes and related bacteria, ribosomal large subunit protein L27 is encoded with a conserved N-terminal extension that is removed to expose residues critical for ribosome function. Bacteria encoding L27 with this N-terminal extension also encode a
Christie, Gail E. +3 more
core +2 more sources

