Results 51 to 60 of about 2,500,121 (245)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Typology of Negation in the Ardalani Variety of Sorani Kurdish [PDF]

open access: yesمطالعات زبان‌‌ها و گویش‌های غرب ایران
The present study aims to explore negation patterns in Ardalani, a variety of central Kurdish (Sorani) spoken mainly in Sanandaj, within the typological framework proposed by Miestamo (2005).
Roya Tabei   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Consequential insights for advancing informal STEM learning and outcomes for students from historically marginalized communities

open access: yesHumanities & Social Sciences Communications
Consequential STEM experiences in informal settings can address issues of equity by fully engaging historically marginalized high school students in complex socio-scientific issues.
Claudia McLaughlin Ludwig   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Getting out: A preliminary analysis of вы- and из-

open access: yesPoljarnyj Vestnik: Norwegian Journal of Slavic Studies, 2009
This article explores the Russian aspectual prefixes вы- and из- from the perspective of cognitive linguistics. It is shown that the two prefixes have very similar meanings that occupy overlapping parts of the same category network. The meanings attested
Tore Nesset   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A Compilation Model for Aspect-Oriented Polymorphically Typed Functional Languages [PDF]

open access: yes, 2007
. Introducing aspect orientation to a polymorphically typed functional language strengthens the importance of type-scoped advices; i.e., advices with their effects harnessed by type constraints. As types are typically treated as compile time entities, it
Chen, Kung   +11 more
core   +1 more source

Implementing concept-based instruction in the heritage language classroom: A pedagogical proposal

open access: yesEuroAmerican Journal of Applied Linguistics and Languages, 2017
Framed within a Sociocultural Theory of Mind approach to Second Language Learning and Development (Lantolf & Poehner, 2014), this article presents a pedagogical proposal for implementing concept-based instruction (C-BI) in the Spanish heritage language ...
Próspero N. García
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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