Results 71 to 80 of about 2,101,677 (317)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Spatial Distribution of Soil Organic Carbon in the Forests of Nepal

open access: yesLand
Soil organic carbon (SOC) is the major constituent of the soil organic matter. SOC stocks are determined by several factors such as altitude, slope, aspect, canopy cover, and vegetation type.
Rajesh Malla, Prem Raj Neupane
doaj   +1 more source

The Basse Mandinka "future"

open access: yesStudies in African Linguistics, 2012
The present paper provides a detailed analysis of the semantic content of the BE…LA formation found in the Basse Mandinka language. It demonstrates that the meaning of this locution corresponds to a complex set of various temporal, aspectual and modal ...
Alexander Andrason
doaj   +1 more source

Preserving Dynamic Reconfiguration Consistency in Aspect Oriented Middleware [PDF]

open access: yes, 2010
Aspect-oriented middleware is a promising technology for the realisation of dynamic reconfiguration in heterogeneous distributed systems. However, like other dynamic reconfiguration approaches, AO-middleware-based reconfiguration requires that the ...
Surajbali, B., Grace, P., Coulson, G.
core  

ASPECT v2.0.0

open access: yes, 2018
<p>We are pleased to announce the release of ASPECT 2.0.0. ASPECT is the Advanced Solver for Problems in Earth's ConvecTion. It uses modern numerical methods such as adaptive mesh refinement, multigrid, and a modular software design to provide ...
Rene Gassmoeller   +3 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A syntactic and semantic study of the tense and aspect system of modern Persian [PDF]

open access: yes, 1990
A survey of previous shcolarship has shown that there is no satisfactory description of the tense and aspect system of Modern Persian. This dissertation is the first attempt to study the syntax and semantics of Modem Persian verb forms in the light of ...
Khomeijani Farahani, Ali Akbar
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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