Results 81 to 90 of about 6,287,498 (310)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Spatial Distribution of Soil Organic Carbon in the Forests of Nepal

open access: yesLand
Soil organic carbon (SOC) is the major constituent of the soil organic matter. SOC stocks are determined by several factors such as altitude, slope, aspect, canopy cover, and vegetation type.
Rajesh Malla, Prem Raj Neupane
doaj   +1 more source

The Basse Mandinka "future"

open access: yesStudies in African Linguistics, 2012
The present paper provides a detailed analysis of the semantic content of the BE…LA formation found in the Basse Mandinka language. It demonstrates that the meaning of this locution corresponds to a complex set of various temporal, aspectual and modal ...
Alexander Andrason
doaj   +1 more source

Understanding the production of dual BEC with sympathetic cooling

open access: yes, 2001
We show, both experimentally and theoretically, that sympathetic cooling of $^{87}$Rb atoms in the $|F=2,m_F=2>$ state by evaporatively cooled atoms in the $|F=1,m_F=-1>$ state can be precisely controlled to produce dual or single condensate in either ...
Aspect, A.   +5 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Temporal deixis in early child Romanian

open access: yesBucharest Working Papers in Linguistics, 2012
This paper investigates the contrastive use of tense-aspect inflections in early childRomanian. It focuses on the use of the prezent, perfect compus and the periphrastic futuremorphologies. It finds evidence of the ability to inflect a significant number
Ioana Stoicescu
doaj  

PRAGMATIC ASPECT OF GODDES OF PANTURA BOOK COVER [PDF]

open access: yes, 2019
Goddes of Pantura is a photography book created by Arum Tresnaningtyas which discuss about dangdut music in the North-coast of Java. Cover works as an exciting main image representative to represent what it is inside—the book.
Desintha, S. (Siti )   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Perspective and the future-in-the-past

open access: yesGlossa, 2017
The paper investigates the future-in-the-past (FiP) as in Peter would (later) see the Fujiyama. FiP can convey an outlook on events that, as the speaker knows, took place later (“objective sense”).
Regine Eckardt
doaj   +2 more sources

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