Results 91 to 100 of about 6,473,940 (330)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Multi-feature Interaction for Aspect Sentiment Triplet Extraction [PDF]

Jisuanji kexue yu tansuo
Aspect sentiment triple extraction is one of the subtasks of aspect-level sentiment analysis, which aims to extract aspect terms, corresponding opinion terms and sentiment polarity in sentence.
CHEN Linying, LIU Jianhua, ZHENG Zhixiong, LIN Jie, XU Ge, SUN Shuihua
doaj   +1 more source

Encoding Syntactic Information into Transformers for Aspect-Based Sentiment Triplet Extraction

IEEE Transactions on Affective Computing
Aspect-based sentiment triplet extraction (ASTE) aims to extract triplets consisting of aspect terms and their associated opinion terms and sentiment polarities from sentences, a relatively new and challenging subtask of aspect-based sentiment analysis ...
Li Yuan, Jin Wang, Liang-Chih Yu, Xuejie Zhang   +3 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A vocabulary-independent generation framework for DBpedia and beyond [PDF]

, 2017
The dbpedia Extraction Framework, the generation framework behind one of the Linked Open Data cloud’s central hubs, has limitations which lead to quality issues with the dbpedia dataset.
De Meester, Ben, Dimou, Anastasia, Hellman, S., Kontokostas, D, Lehmann, J., Mannens, Erik, Maroy, Wouter, Verborgh, Ruben   +7 more
core  

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Named Entity Recognition in Twitter using Images and Text

, 2017
Named Entity Recognition (NER) is an important subtask of information extraction that seeks to locate and recognise named entities. Despite recent achievements, we still face limitations with correctly detecting and classifying entities, prominently in ...
Esteves, Diego, Lehmann, Jens, Napolitano, Giulio, Peres, Rafael   +3 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Ars Informatica -- Ars Electronica: Improving Sonification Aesthetics [PDF]

, 2005
In this paper we discuss æsthetic issues of sonifications. We posit that many sonifications have suffered from poor acoustic ecology which makes listening more difficult, thereby resulting in poorer data extraction and inference on the part of the ...
Vickers, Paul
core