Results 81 to 90 of about 832,569 (293)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

SmartTips: Online Products Recommendations System Based on Analyzing Customers Reviews

open access: yesApplied Sciences, 2022
Online customers’ opinions represent a significant resource for both customers and enterprises to extract much information that helps them make the right decision. Finding relevant data while searching the internet is a big challenge for web users, known
Noaman M. Ali   +3 more
doaj   +1 more source

Interdigitation between surface-anchored polymer chains and an elastomer : consequences for adhesion promotion

open access: yes, 2004
We study the adhesion between a cross-linked elastomer and a flat solid surface where polymer chains have been end-grafted. To understand the adhesive feature of such a system, one has to study both the origin of the grafted layer interdigitation with ...
Brown H. R.   +13 more
core   +2 more sources

Supervised Opinion Aspect Extraction by Exploiting Past Extraction Results

open access: yesCoRR, 2016
One of the key tasks of sentiment analysis of product reviews is to extract product aspects or features that users have expressed opinions on. In this work, we focus on using supervised sequence labeling as the base approach to performing the task. Although several extraction methods using sequence labeling methods such as Conditional Random Fields ...
Lei Shu 0004   +3 more
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Aspect term extraction based on word embedding

open access: yesТруды Института системного программирования РАН, 2018
There are many sites in the Internet that allow users to share their opinions and write reviews about all kinds of goods and services. These views may be useful not only for other users, but also for companies which want to track their own reputation and
D. O. Mashkin, E. V. Kotelnikov
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Multi-feature Interaction for Aspect Sentiment Triplet Extraction [PDF]

open access: yesJisuanji kexue yu tansuo
Aspect sentiment triple extraction is one of the subtasks of aspect-level sentiment analysis, which aims to extract aspect terms, corresponding opinion terms and sentiment polarity in sentence.
CHEN Linying, LIU Jianhua, ZHENG Zhixiong, LIN Jie, XU Ge, SUN Shuihua
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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