Results 41 to 50 of about 160,518 (194)

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Serum level directed itraconazole therapy in allergic bronchopulmonary aspergillosis

, 2016
Background Itraconazole (ITZ) is an alternative to steroids in the treatment of allergic bronchopulmonary aspergillosis (ABPA) but therapeutic drug monitoring (TDM) is warranted due to erratic absorption and early relapse.
Agarwal, Kshitij, S.N. Gaur, Kshitij Agarwal, Anuradha Chowdhary, Roger Bruggemann, Meis, J.F., Bruggemann, Roger, Gaur, S.N., Chowdhary, Anuradha, J.F. Meis   +9 more
core   +1 more source

Real‐World Use of Rezafungin for the Treatment of Challenging Aspergillus Infections

Mycoses, Volume 69, Issue 11, November 2026.
ABSTRACT Background Aspergillus infections can pose significant treatment challenges, due in part to increasing triazole resistance. Clinical insight is needed to understand the potential for rezafungin, a next‐generation echinocandin with once‐weekly dosing, to address some limitations of current treatments for Aspergillus infections.
Neil Stone, Pablo Bachiller‐Luque, Simone Giuliano, Sumita Pai, Berta Pernas, Carolina Garcia‐Vidal, Netta Tyler, Sara Ferin, Carlo Tascini, Ana Fernández Cruz   +9 more
wiley   +1 more source

A Retrospective Review of 1821 Cases of Eosinophilia in a Single‐Center Study in Eastern China

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Objective: Our study aims to explore the types of diseases that may cause eosinophilia and the changes in the disease spectrum of different degrees of eosinophilia. Methods We retrospectively analyzed patients who were admitted to the First Affiliated Hospital of Soochow University from July 1, 2023 to June 30, 2024, and had at least twice ...
Yanan Ma, Linlin Wang, Yuexin Cheng, Xiaofei Yang, Suning Chen   +4 more
wiley   +1 more source

Fighting diagnostic confirmation bias: Cystic fibrosis, allergic bronchopulmonary aspergillus, or both?

Clinical Case Reports, 2021
As diagnostic algorithms for cystic fibrosis (CF) continue to evolve, education of general practitioners is essential to prevent delayed diagnosis of CF and allow prompt referral to CF centers.
Patricia Choi, Laura Bauler, M. Myrtha Gregoire‐Bottex   +2 more
doaj   +1 more source

Bronchiectasis as the Sentinel Manifestation of ANCA‐Associated Vasculitis: A Case Report and Literature Review

Respirology Case Reports, Volume 14, Issue 10, October 2026.
A 74‐year‐old woman was treated for 7 years as culture‐negative bronchiectasis before palpable purpura, haemoptysis, and acute kidney injury revealed MPO‐ANCA vasculitis with pauci‐immune crescentic glomerulonephritis. Rituximab‐based induction produced near‐complete resolution of the pulmonary consolidations and sustained clinical remission at 15 ...
Andrew Kim, Celine Vartany, Siddhanth Hegde, Kristie Lau, Lynette Tatosyan, Brannen Liang   +5 more
wiley   +1 more source

Fungal Fantasies: Series of Pulmonary Mycotic Manifestations [PDF]

Indian Journal of Respiratory Care
Fungal involvement in the lungs, known as pulmonary mycosis, can range from mild allergic disease to life-threatening invasive fungal conditions, particularly among immunocompromised individuals and those with underlying lung diseases.
R Anand, S Raghul Raj, S Arun Pandiyan
doaj   +1 more source

T-cell epitope-based vaccine prediction against Aspergillus fumigatus: a harmful causative agent of aspergillosis

Journal of Genetic Engineering and Biotechnology, 2022
Background Among the most common causes of invasive aspergillosis and acute bronchopulmonary aspergillosis is Aspergillus fumigatus. Transmission with A.
Darakshan Jabin, Ajay Kumar
doaj   +1 more source

Therapeutic potential of a Bax inhibitor‐1/TMBIM6 antagonist (BIA) and its analogues in Aspergillus fumigatus‐induced asthma via dual targeting of AKT and epithelial‐derived inflammatory cytokines

British Journal of Pharmacology, Volume 183, Issue 19, Page 5975-5991, October 2026.
Background and Purpose Aspergillus fumigatus (A. fumigatus) exposure causes of severe allergic asthma, characterized by airway inflammation and epithelial dysfunction. TMBIM6 (Bax inhibitor‐1) has been implicated in airway epithelial stress responses and AKT signalling.
Young‐Jin Yu, Ahsan Ullah, Jisun Kim, Mehedi Hasan Bappi, Yerim Heo, Jin Hee Ahn, Hyun‐Kyoung Kim, Han‐Jung Chae   +7 more
wiley   +1 more source

An unusual cause of hilar lymphadenopathy

Lung India, 2006
Allergic bronchopulmonary aspergillosis is an uncommon condition characterized by hypersensitivity to aspergillus antigen. It commonly presents as refractory asthma, fleeting pulmonary opacities and bronchiectasis.
Agarwal Ritesh, Reddy Chandana, Gupta D
doaj