Geographic variation in the aetiology, epidemiology and microbiology of bronchiectasis [PDF]
, 2018 Bronchiectasis is a disease associated with chronic progressive and irreversible dilatation of the bronchi and is characterised by chronic infection and associated inflammation.
A Fairs +124 more
core +2 more sources
The Aetiology of Elevated Total Serum Immunoglobulin E in Children
Acta Paediatrica, Volume 114, Issue 11, Page 2993-2999, November 2025.ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä +2 more
wiley +1 more source
Evidence Supporting a Role for Mammalian Chitinases in Efficacy of Caspofungin against Experimental Aspergillosis in Immunocompromised Rats [PDF]
, 2013 Objectives:Caspofungin, currently used as salvage therapy for invasive pulmonary aspergillosis (IPA), strangely only causes morphological changes in fungal growth in vitro but does not inhibit the growth. In vivo it has good efficacy.
Bakker-Woudenberg, I.A.J.M. (Irma) +6 more
core +5 more sources
Asthma and aspergillosis: Which One causes another
Biomedical and Biotechnology Research Journal, 2020 The respiratory system of the human body is always under exposure to a great number of fungal spores every day. Asexual spores of Aspergillus are the most frequent type occurring in various environments.
Roaa Noori Ali +1 more
doaj +1 more source
Estimated Burden of Serious Fungal Infections in Mozambique
Journal of Fungi, 2018 Mozambique is a sub-Saharan African country with limited information on the burden of fungal disease. We estimate the burden of serious fungal infections for the general healthy population and for those at risk, including those infected with HIV ...
Jahit Sacarlal, David W. Denning
doaj +1 more source
Interleukin-4 Causes Susceptibility to Invasive Pulmonary Aspergillosis through Suppression of Protective Type I Responses [PDF]
, 2017 Aspergillus fumigatus, an opportunistic fungal pathogen, causes multiple allergic and non-allergic airway diseases. Invasive pulmonary aspergillosis (IPA) is a nonallergic, life-threatening disease of immunocompromised patients. In a murine model of IPA,
Bacci, Angela +10 more
core
Cytokines induce effector T-helper cells during invasive aspergillosis; what we have learned about T-helper cells? [PDF]
, 2015 Invasive aspergillosis caused by Aspergillus species (Aspergillus fumigatus, A. flavus and A. terreus) is life-threatening infections in immunocompromised patients.
Agam P. Singh +5 more
core +2 more sources
The Changing Transplant Landscape in the Era of Elexacaftor/Tezacaftor/Ivacaftor: A Word of Caution
Clinical Transplantation, Volume 39, Issue 10, October 2025.ABSTRACT Background Elexacaftor/tezacaftor/ivacaftor (ETI) has dramatically changed the landscape of cystic fibrosis (CF) care, including in those who require lung transplantation. The objectives of the study were to describe the cohort demographics and outcomes of primary lung transplant recipients before and after the availability of ETI.
Julie Semenchuk +8 more
wiley +1 more source
Severe Allergic Bronchopulmonary Mycosis and Long-Term Follow-Up
Case Reports in Immunology, 2018 Allergic bronchopulmonary aspergillosis (ABPA) is the most common immunologic reaction following fungal allergen exposure in asthmatic patients. A less frequent syndrome in response to other fungal species like candida is allergic bronchopulmonary ...
Hossein Esmaeilzadeh +5 more
doaj +1 more source