Results 61 to 70 of about 83,696 (263)

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation [PDF]

, 2020
The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus. Deletion of a gene encoding a putative deacetylase, Agd3, leads to defects in GAG deacetylation, biofilm formation, and ...
A Ghafoor, A Morin, AB Boraston, AW Blake, C Bundalovic-Torma, C Guerrero, C Ryder, C Steentoft, C Vuong, CM Payne, Collaborative Computational Project Number 4., CS Cummins, DC Sheppard, DE Blair, DE Blair, DJ Little, DJ Little, DJ Little, E Andrés, E Potterton, EN Kitova, F Le Mauff, F Sievers, FN Gravelat, FN Gravelat, GB Whitfield, GD Brown, GM Sheldrick, GM Sheldrick, H Aragunde, H Ashkenazy, H Ostapska, H Takada, H Zakariassen, J Hoßbach, J Sun, JA Jorge, JA Jorge, JJ Distler, JJ Tesmer, JL Reissig, JW Jensen, K Miyazawa, K Mizutani, KM Colvin, LA Kelley, LK Jennings, LS Marmont, M Gonzalez, M Oda, M Strong, MD Winn, MJ Lee, MJ Lee, MM Shaik, N Nwe, NA Baker, NC Bamford, NC Bamford, P Emsley, P Ruperez, P Vasseur, PC Bardalaye, PD Adams, PD Adams, RC Edgar, RE Lewis, S Jana, S Kaur, S Kumar, SC Potter, SF Altschul, T Fontaine, T Inoue, V Pokrovskaya, VE Fadouloglou, VK Köseoğlu, W Vollmer, W Wang, X Wang, X-L Li, Y Araki, Y Itoh, Y Kidani, Y Kidani   +84 more
core   +3 more sources

Correlation between serum galactomannano level and Aspergillus fumigatus specific antibody in patients with allergic bronchopulmonary aspergillus recurrence [PDF]

Jichu yixue yu linchuang
Objective To explore the relationship between serum galactomannano (GM) level and specific antibody level of Aspergillus fumigatus in patients with allergic bronchopulmonary aspergillus (ABPA) recurrence.
WANG Wentao, TAN Wei
doaj   +1 more source

An investigation into the transcription factors and regulatory mechanisms of Aspergillus

Food Safety and Health, EarlyView.
Foodborne pathogen Aspergillus, a prevalent etiologic agent among filamentous fungi, are distinguished by a significant repertoire of transcription factors encoded within their genomes. These regulatory proteins are instrumental in orchestrating key biological processes, including cellular growth, secondary metabolite biosynthesis, mycotoxin production,
Yuxin Qin, Huawei Yu, Jun Tian
wiley   +1 more source

Infection of the pleura by Aspergillus fumigatus [PDF]

Thorax, 1970
Pleural aspergillosis occurs mostly in established cases of pleural empyema with a broncho-pleural fistula. Ten such patients are reported here: in all, Aspergillus fumigatus infection was related to tuberculosis. In three cases with an active, sputum-positive tuberculous process the pleural empyema was a complication of spontaneous pneumothorax in two,
Krakówka P, Ewa Rowinska, Halweg H
openaire   +3 more sources

Profile and functional analysis of small RNAs derived from Aspergillus fumigatus infected with double-stranded RNA mycoviruses

BMC Genomics, 2017
Background Mycoviruses are viruses that naturally infect and replicate in fungi. Aspergillus fumigatus, an opportunistic pathogen causing fungal lung diseases in humans and animals, was recently shown to harbour several different types of mycoviruses.
Selin Özkan, Irina Mohorianu, Ping Xu, Tamas Dalmay, Robert H. A. Coutts   +4 more
doaj   +1 more source

The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps. [PDF]

PLoS Pathogens, 2015
Of the over 250 Aspergillus species, Aspergillus fumigatus accounts for up to 80% of invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and N-acetyl-galactosamine (GalNAc) that ...
Mark J Lee, Hong Liu, Bridget M Barker, Brendan D Snarr, Fabrice N Gravelat, Qusai Al Abdallah, Christina Gavino, Shane R Baistrocchi, Hanna Ostapska, Tianli Xiao, Benjamin Ralph, Norma V Solis, Mélanie Lehoux, Stefanie D Baptista, Arsa Thammahong, Robert P Cerone, Susan G W Kaminskyj, Marie-Christine Guiot, Jean-Paul Latgé, Thierry Fontaine, Donald C Vinh, Scott G Filler, Donald C Sheppard   +22 more
doaj   +1 more source

Rapid Diagnostic Testing for Infective Endocarditis and Myocarditis Using Nanopore Targeted Sequencing

iLABMED, EarlyView.
This research presents a method based on nanopore targeted sequencing (NTS) with pathogen‐specific panels for testing infective endocarditis (IE) and myocarditis. The NTS achieved a detection limit of 20 copies/test for the IE target panel and 10 copies/test for the myocarditis target panel.
Aisi Fu, Xian Wang, Zhiyong Shen, Jiashuang Gu, Ting Zhang, Feiyan Wang, Shiyu Jia, Linmei Yang, Feng Li, Jie Geng, Jun Cheng   +10 more
wiley   +1 more source

Aspergillus fumigatus preexposure worsens pathology and improves control of Mycobacterium abscessus pulmonary infection in mice [PDF]

, 2018
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. Mutations in this chloride channel lead to mucus accumulation, subsequent recurrent pulmonary infections, and ...
Elsegeiny, Waleed, Gopal, Radha, Khader, Shabaana A, Kolls, Jay, McAleer, Jeremy P, Mehta, Shail, Monin, Leticia, Oury, Tim D   +7 more
core   +2 more sources

T-cell epitope-based vaccine prediction against Aspergillus fumigatus: a harmful causative agent of aspergillosis

Journal of Genetic Engineering and Biotechnology, 2022
Background Among the most common causes of invasive aspergillosis and acute bronchopulmonary aspergillosis is Aspergillus fumigatus. Transmission with A.
Darakshan Jabin, Ajay Kumar
doaj   +1 more source

Safety and Feasibility of Pulsed Electric Field Ablation for Early‐Stage Non‐Small Cell Lung Cancer Prior to Surgical Resection

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Methods Surgery remains the standard of care for non‐small cell lung cancer (NSCLC) but is applicable to ≤ 30% of patients. Pulsed Electric Fields (PEF) ablation uses short‐duration, high‐voltage electrical pulses to induce cell death without relying on thermal mechanisms.
Marcelo Jimenez, Javier Flandes, Erik H. F. M. van der Heijden, Calvin S. H. Ng, Jeffrey S. Iding, José F. Garcia‐Hierro, Borja Recalde‐Zamacona, Roel L. J. Verhoeven, Rainbow W. H. Lau, Alicia Moreno‐Gonzalez, Beryl A. Hatton, Partha Seshaiah, Maria B. Plentl, William S. Krimsky   +13 more
wiley   +1 more source