Results 61 to 70 of about 237,147 (278)

Humoral Immunity Against Aspergillus fumigatus

Mycopathologia, 2023
Aspergillus fumigatus is one the most ubiquitous airborne opportunistic human fungal pathogens. Understanding its interaction with host immune system, composed of cellular and humoral arm, is essential to explain the pathobiology of aspergillosis disease spectrum.
Sarah Dellière, Vishukumar Aimanianda
openaire   +2 more sources

Azole-ResistantAspergillus fumigatus, Iran

Emerging Infectious Diseases, 2013
To the Editor: Aspergillus fumigatus causes a variety of diseases in humans. The drugs recommended for treatment of Aspergillus diseases are the mold-active azole antifungal drugs (1). However, a wide range of mutations in A. fumigatus confer azole resistance, which commonly involves modifications in the cyp51A gene (2), the target for azole antifungal
Seyedmousavi, S., Hashemi, S.J., Zibafar, E., Zoll, J., Hedayati, M.T., Mouton, J.W., Melchers, W.J.G., Verweij, P.E.   +7 more
openaire   +5 more sources

The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]

, 2017
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
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Non-fumigatus Aspergillus-associated pulmonary events: a diagnostic challenge

Journal of Clinical Microbiology
Diagnosing pulmonary diseases caused by non-fumigatus Aspergillus species remains challenging. We conducted a single-center, retrospective observational study in a French Respiratory Medicine Department.
Cendrine Godet, Valentin Joste, Jean-Pierre Frat, Antoine Khalil, Vincent Bunel, Tiphaine Goletto, Thomas Maitre, Armelle Marceau, Domitille Mouren, Lise Morer, Mathilde Salpin, Gaëlle Weisenburger, Camille Taillé, Jacques Cadranel, Hervé Mal, Christine Bonnal   +15 more
doaj   +1 more source

Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]

, 2017
This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba, van der Lee, Henrich, Verweij, Paul, Warris, Adilia   +3 more
core   +1 more source

Mutations in hmg1, Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus

mBio, 2019
Aspergillus fumigatus is the predominant pathogen of invasive aspergillosis, a disease state credited with over 200,000 life-threatening infections annually.
J. Rybak, Wenbo Ge, N. Wiederhold, J. Parker, S. Kelly, P. Rogers, J. Fortwendel   +6 more
semanticscholar   +1 more source

Therapeutic potential of Calotropis gigantea extract against invasive pulmonary aspergillosis: In vitro and in vivo study

Asian Pacific Journal of Tropical Biomedicine, 2022
Objective: To characterize the antifungal activity of methanolic leaf extract of Calotropis gigantea alone or in combination with amphotericin B against invasive pulmonary aspergillosis in mice. Methods: GC/MS was used for analysis of active constituents
Enas M Ali, Manal A Alfwuaires, Gehan M Badr   +2 more
doaj   +1 more source

Estimating fugitive bioaerosol releases from static compost windrows: feasibility of portable wind tunnel approach [PDF]

, 2005
An assessment of the fugitive release of bioaerosols from static compost piles was conducted at a green waste composting facility in South East England; this representing the initial stage of a programme of research into the influence of process ...
Longhurst, Philip J., Pollard, Simon J. T., Sarkar, Ujjaini, Taha, M. P. M.   +3 more
core   +1 more source

The presence of Aspergillus fumigatus is associated with worse respiratory quality of life in cystic fibrosis.

Journal of Cystic Fibrosis, 2020
BACKGROUND The clinical effects of Aspergillus fumigatus in the cystic fibrosis (CF) airway, with the exception of allergic bronchopulmonary aspergillosis, is unclear.
G. Hong, K. Alby, S. C. Ng, Victoria Fleck, Christina Kubrak, R. Rubenstein, D. Dorgan, S. Kawut, D. Hadjiliadis   +8 more
semanticscholar   +1 more source

Gene essentiality inAspergillus fumigatus [PDF]

Medical Mycology, 2006
Products of essential genes of Aspergillus fumigatus are seen as potential targets for antifungal drugs, and both functional screens and bioinformatics approaches have been used to help identify such genes. The random screening approach makes use of the deletion of one copy of a gene in a diploid, and failure to recover the deletant during ...
Turner, G., Allen, G. J., Keszenman-Pereyra, D., Bromley, M. J.   +3 more
openaire   +3 more sources