Results 61 to 70 of about 50,941 (289)

Stridor Is an Independent Risk Factor for Mortality and Disease Progression in Patients with Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background and aim Stridor and sleep apnea syndrome (SAS) are common in multiple system atrophy (MSA). Retrospective cohort studies have yielded conflicting results regarding the consequences of stridor and SAS on the disease course. This study aimed to assess the prognostic significance of stridor and SAS, as well as the potential survival ...
Pauline Dodet, Cecile Proust‐Lima, Federico Sirna, David Bendetowicz, Giulia Lazzeri, Rachel Debs, Anna Delamarre, Margaux Dunoyer, Margherita Fabbri, Claire Georges, Imad Ghorayeb, David Grabli, Cécile Londner, Anne Pavy‐Le Traon, Maxime Patout, Olivier Rascol, Isabelle Arnulf, Alexandra Foubert‐Samier, Wassilios G. Meissner   +18 more
wiley   +1 more source

Diagnostic Value of Exome Sequencing in Isolated Polyhydramnios

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield of exome sequencing (ES) in isolated polyhydramnios. Methods This retrospective study included 40 cases of isolated polyhydramnios. All patients underwent screening for gestational diabetes mellitus (GDM) and chromosomal microarray analysis (CMA).
Vered Offen Glassner, Adi Botvinik, Adi Mory, Adi Reches, Karina Krajden Haratz, Britannia Morgan Fleming, Hagit Baris Feldman, Lena Sagi‐Dain, Mordechai Shohat, Rayna Joy Goldstein, Yuval Yaron, Michal Levy   +11 more
wiley   +1 more source

Chest Compressions During Sustained Inflation During Cardiopulmonary Resuscitation in Newborn Infants Translating Evidence From Animal Studies to the Bedside

JACC: Basic to Translational Science, 2019
Summary: Newborn infants receiving chest compressions in the delivery room have a high incidence of mortality (41%) and short-term neurological morbidity (e.g., 57% hypoxic-ischemic encephalopathy and seizures).
Georg M. Schmölzer, MD, PhD
doaj   +1 more source

The Clinical Significance of Fetal Intra-Abdominal Umbilical Vein Varix: A Comparative Study. [PDF]

J Ultrasound Med
Objectives To clarify the clinical significance and optimal management of fetal intra‐abdominal umbilical vein varix (FIUVV). Methods A retrospective study comparing composite asphyxia‐related adverse outcomes including stillbirth, cesarean delivery due to non‐reassuring fetal heart rate (CD NRFHR), Apgar <7, Cord pH <7, neonatal intensive care unit ...
Zloto K, Wiener A, Bibar N, Meyer R, Massarwa A, Fishel Bartal M, Weissmann-Brenner A, Kassif E, Weissbach T.   +8 more
europepmc   +2 more sources

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

Pediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao, Zhongying Yang, Yu He, Jianhua Wei, Luo Ren, Enmei Liu, Na Zang   +6 more
wiley   +1 more source

Postnatal Growth Patterns and Deviations in Singleton and Twin Infants: A Prospective Cohort Study on Infants Appropriate and Small for Gestational Age

Pediatric Discovery, EarlyView.
This is a cohort study including 340 infants stratified into small or appropriate for gestational age. We examined their early physical growth characteristics and described the differences in etiology and catch‐up growth patterns between singleton and twin small for gestational age infants.
Yannan Wan, Ting Pan, Zhanzhan Zhang, Yuanfeng Zhong, Qian Chen, Xuelin Xia, Lin Zhu, Li Chen, Xuan Zhang   +8 more
wiley   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates, Michael Zientek, Kunal S. Taskar, Wen Lin, Tycho Heimbach, Stefan Willmann, Jessica Rehmel, Neil Parrott, Michael Hanley, Justine Badee, Yuan Chen, Susan Cole, Loeckie De Zwart, Sebastian Haertter, Rongrong Jiang, Masakatsu Kotsuma, Guiqing Liang, Yu‐Wei Lin, Jing Liu, Ying Ou, Juliane Rascher, Naveed A. Shaik, Jan Wahlstrom, Xiaofeng Wang, Guangqing Xiao, Ka Lai Yee, S. Y. Amy Cheung   +26 more
wiley   +1 more source

Intramuscular versus intravenous epinephrine administration in a pediatric porcine model of cardiopulmonary resuscitation

Resuscitation Plus
Background: American Heart Association Pediatric Life Support guidelines recommend epinephrine administration via intravenous (IV) or intraosseous (IO) route, with endotracheal (ET) administration admissible in the absence of IV/IO access.
Megan O’Reilly, Janice A. Tijssen, Tze-Fun Lee, Marwa Ramsie, Po-Yin Cheung, Georg M. Schmölzer   +5 more
doaj   +1 more source

Global Health Governance Cannot Keep Relying on the Development‐Goals Model to Effectively Address Health Inequalities Around the World

Sustainable Development, EarlyView.
ABSTRACT The Sustainable Development Goals (SDGs) are nearing their end in 2030, and it is highly unlikely that many of the SDGs would be met by the target date. This calls for the urgent need for an upgraded approach or a new strategy from the “development‐goals” model.
Funom Theophilus Makama
wiley   +1 more source

Could Perinatal Asphyxia Induce a Synaptopathy? New Highlights from an Experimental Model

Neural Plasticity, 2017
Birth asphyxia also termed perinatal asphyxia is an obstetric complication that strongly affects brain structure and function. Central nervous system is highly susceptible to oxidative damage caused by perinatal asphyxia while activation and maturity of ...
María Inés Herrera, Matilde Otero-Losada, Lucas Daniel Udovin, Carlos Kusnier, Rodolfo Kölliker-Frers, Wanderley de Souza, Francisco Capani   +6 more
doaj   +1 more source