Results 91 to 100 of about 312,145 (352)

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu   +9 more
wiley   +1 more source

Hydroxychloroquine Associated with Lower Glomerular Filtration Rate Decline in Lupus Nephritis

open access: yesArthritis Care &Research, Accepted Article.
Background Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical. Therefore, we analyzed data from our
Shivani Garg   +9 more
wiley   +1 more source

Aspirin use correlates with survival in women with clear cell ovarian cancer

open access: yesGynecologic Oncology Reports, 2018
Data from colon, breast and prostate cancers suggest that aspirin users have reduced mortality. While the direct mechanism remains uncertain, aspirin can suppress the COX-dependent and independent pathways involved in tumor progression.
Alyssa M. Wield   +5 more
doaj   +1 more source

Global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis burden, 1990–2021

open access: yesArthritis Care &Research, Accepted Article.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen   +14 more
wiley   +1 more source

Association Between Aspirin Use and Risk of Hepatocellular Carcinoma

open access: yesJAMA Oncology, 2018
Importance Prospective data on the risk of hepatocellular carcinoma (HCC) according to dose and duration of aspirin therapy are limited. Objective To examine the potential benefits of aspirin use for primary HCC prevention at a range of doses and ...
Tracey G. Simon   +10 more
semanticscholar   +1 more source

Serum uric acid levels in older adults: Associations with clinical outcomes and implications for reference intervals in those aged 70 years and over

open access: yesArthritis Care &Research, Accepted Article.
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard   +15 more
wiley   +1 more source

Association of early aspirin use with 90-day mortality in patients with sepsis: an PSM analysis of the MIMIC-IV database

open access: yesFrontiers in Pharmacology
ObjectiveIn addition to its antiplatelet and anti-inflammatory properties, aspirin inhibits bacterial proliferation directly. The potential benefits of aspirin may enhance the prognosis for sepsis patients.
Chunsheng Huang   +3 more
doaj   +1 more source

Prevalence and Risk Factors for Aspirin Resistance in Elderly Patients With Type 2 Diabetes

open access: yesInternational Journal of Gerontology, 2011
Background: Aspirin resistance in patients with diabetes is recognized. However, the prevalence and related risk factors for aspirin resistance in elderly patients with Type 2 diabetes have not been reported, which is why we undertook this study. Methods:
Lin Liu   +9 more
doaj   +1 more source

Perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia

open access: yesArthritis Care &Research, Accepted Article.
Background/Aims Asymptomatic hyperuricemia is a precursor of gout and is also associated with cardiovascular disease and chronic kidney disease. The aim of this study was to understand perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia.
Nicola Dalbeth   +19 more
wiley   +1 more source

Aspirin Desensitization and Percutaneous Coronary Intervention in a Patient with Aspirin Hypersensitivity and Acute Coronary Syndrome: A Case Report

open access: yesJournal of Nepal Medical Association
Hypersensitivity to aspirin is rare disorder occurring in 1.88% of the patients. Aspirin-hypersensitive patients requiring single antiplatelet agent may be treated with clopidogrel, an alternative antiplatelet agent.
Suman Acharya   +7 more
doaj   +1 more source

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