Results 91 to 100 of about 372,006 (379)

No Headache for PIPs: A PIP Potential for Aspirin Outperforms Other Machine-Learned Potentials [PDF]

J. Chem. Theory Comput. 2024
Assessments of machine-learned (ML) potentials are an important aspect of the rapid development of this field. We recently reported an assessment of the linear-regression permutationally invariant polynomial (PIP) method for ethanol, using the widely used (revised) MD17 dataset. We demonstrated that the PIP approach outperformed numerous other methods,
arxiv   +1 more source

Gaussian Processes with Spectral Delta kernel for higher accurate Potential Energy surfaces for large molecules [PDF]

arXiv, 2021
The interpolation of high-dimensional potential energy surfaces (PESs) is commonly done with physically-inspired deep-neural network models. In this work, we illustrate that Gaussian Processes (GPs) are also capable of interpolating high-dimensional complex physical systems.
arxiv  

Discontinuation of Immunotherapy in Patients With Relapsing Myelitis Without AQP4/MOG Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study assesses the outcomes of immunotherapy discontinuation in patients with relapsing seronegative idiopathic myelitis (SIM), a condition that remains uninvestigated due to its rarity. We reviewed records from 77 patients with relapsing SIM at the National Cancer Center of Korea, focusing on 11 who discontinued treatment after a median ...
Ki Hoon Kim, You‐Ri Kang, Jae‐Won Hyun, Su‐Hyun Kim, Ho Jin Kim   +4 more
wiley   +1 more source

Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. [PDF]

, 2006
BACKGROUND AND PURPOSE: Aspirin resistance may be relatively common and associated with adverse outcome. Meta-analysis has clearly shown that 75 mg plain aspirin is the lowest effective dose; however, it is not known whether the recent increased use of ...
Byrne, Michael F, Conroy, Ronán, Cox, Dermot, Dooley, Michelle, Fitzgerald, Desmond J, Maree, Andrew O   +5 more
core   +1 more source

IDIOSYNCRASY TO ASPIRIN [PDF]

Journal of the American Medical Association, 1911
InThe JournalI recently read a communication 1 in regard to idiosyncrasy to aspirin, of which I had an almost parallel case on November 19. On the advice of a friend a young man took a five-grain tablet of aspirin for headache. In about one hour, still suffering, he took another, and then lay down on a cot in his office.
openaire   +2 more sources

Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao, Hongliang Ge, Chenchao Lin, Xiyue Wu, Jianwu Chen   +4 more
wiley   +1 more source

Amniotic Fluid Ingestion Enhances\ud Opioid-Mediated But Not\ud Nonopioid-Mediated Analgesia [PDF]

, 1990
Ingestion of amniotic fluid or placenta by rats has been shown to enhance several types of opioid-mediated analgesia: that induced by morphine, footshock, vaginal/cervical stimulation, and late pregnancy.
Barton, Debra, Kristal, Dr. Mark B., Tarapacki, J. A.   +2 more
core  

Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial. [PDF]

, 2020
BACKGROUND: Preterm birth remains a common cause of neonatal mortality, with a disproportionately high burden in low-income and middle-income countries.
Achieng, Emmah, ASPIRIN Study Group, Bose, Carl L., Carlo, Waldemar A., Chicuy, Javier, Chomba, Elwyn, Das, Prabir, Derman, Richard J., Esamai, Fabian, Figueroa, Lester, Garces, Ana, Goco, Norman, Goldenberg, Robert L., Goudar, Shivaprasad S., Hemingway-Foday, Jennifer, Hibberd, Patricia L., Hoffman, Matthew K., Jessani, Saleem, Kodkany, Bhalachandra S., Koso-Thomas, Marion, Krebs, Nancy F., Kurhe, Kunal, Liechty, Edward A., Lokangaka, Adrien, McClure, Elizabeth M., Metgud, Mrityunjay, Miodovnik, Menachem, Moore, Janet, Mwapule, Abigail, Mwenechanya, Musaku, Nolen, Tracy L., Nyongesa, Paul, Okitawutshu, Jean, Patel, Archana, Saleem, Sarah, Silver, R., Somannavar, Manjunath, Tshefu, Antoinette, Zehra, Farnaz   +38 more
core   +1 more source

Exploring the equity of GP practice prescribing rates for selected coronary heart disease drugs: a multiple regression analysis with proxies of healthcare need [PDF]

, 2005
Background There is a small, but growing body of literature highlighting inequities in GP practice prescribing rates for many drug therapies. The aim of this paper is to further explore the equity of prescribing for five major CHD drug groups and to ...
A Gibson, A Majeed, A Majeed, A Majeed, A Williams, AM Tod, Antony S St Leger, B Hope, BH Foundation, C Baxter, C Packham, C Packham, D Health, D Health, D Health, D Health, DC Lloyd, DC Lloyd, EUROASPIREII Group., FA Majeed, FA Majeed, FDA Reid, G Davey-Smith, G Davey-Smith, GC Fonarow, H Cooper, H Tunstall-Pedoe, J Bedson, J Hippisley-Cox, J Tudor Hart, JHS Unit, JI Mann, JY Nazroo, K Gardner, M Frischer, M Goddard, M Pringle, M Whitehead, M Whitehead, MC MacLeod, MG Hunink, MG Patel, N Bradshaw, N Chaturvedi, N Danchin, N Rice, NC Campbell, NHS Centre for Reviews and Dissemination, ON Statistics, P Jousilahti, P Primatesta, P Suadicani, P Townsend, Paul R Ward, Peter R Noyce, PG Steg, PH Whincup, PR Ward, PR Ward, PR Ward, PS Unit, PS Unit, R Bhopal, R Bhopal, RM Haynes, S Hopper, S Kerrison, S Langham, S Peckham, SM Bogle, SR Chapman, SS Gottlieb, T Crayford, T Morton-Jones, T Walley, TJ Wang, V Salomaa, WH Organisation.   +77 more
core   +4 more sources

Evaluating Treatment Prioritization Rules via Rank-Weighted Average Treatment Effects [PDF]

arXiv, 2021
There are a number of available methods for selecting whom to prioritize for treatment, including ones based on treatment effect estimation, risk scoring, and hand-crafted rules. We propose rank-weighted average treatment effect (RATE) metrics as a simple and general family of metrics for comparing and testing the quality of treatment prioritization ...
arxiv