Results 131 to 140 of about 239,825 (303)

Aspirin-ticagrelor use after mild acute ischemic stroke: Findings from the get with the guidelines-stroke registry

Journal of Stroke and Cerebrovascular Diseases
Background: Recent guidelines suggest that aspirin-ticagrelor may be considered for stroke prevention after mild acute ischemic stroke. However, it is unclear how commonly this dual antiplatelet therapy (DAPT) regimen is used in practice.
Ava L. Liberman, MD, Cenai Zhang, BS, Sara K. Rostanski, MD, Hooman Kamel, MD MS, Babak B. Navi, MD MS, Natalie T. Cheng, MD, Radhika Sundararajan, MD PhD, Steven R. Messe, MD, Gregg C. Fonarow, MD, Shyam Prabhakaran, MD MS, Ying Xian, MD PhD   +10 more
doaj   +1 more source

Statin Monotherapy Not Inferior to Aspirin or Combined Aspirin and Statins Reducing the Incidences of Cirrhosis, HCC, and Mortality in MAFLD/MASH Patients: A Population Cohort Study [PDF]

Chern-Horng Lee,1 Yu-Han Huang,2 Tzu-Ju Hsu,3 Tzung-Hai Yen,4 Sen-Yung Hsieh5,6 1Department of Geriatric Medicine and General Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, 333, Taiwan; 2Department of Management Office for ...
Huang YH, Yen TH, Lee CH, Hsieh SY, Hsu TJ   +4 more
core  

Acetylsalicylic-acid (aspirin) induces resistance to tobacco mosaic-virus in tobacco

, 1979
Tobacco cv. Xanthi-nc becomes resistant to tobacco mosaic virus (TMV) and produces b proteins when injected with the interferon inducer polyacrylic acid.
White, R. F.
core   +1 more source

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

Advanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo, Nuria Matesanz, Jorge‐Luis Torres, Alba C. Arcones, Juan Ignacio Jiménez‐Loygorri, Alfonso Mora, Leticia Herrera‐Melle, Luis Leiva‐Vega, Maria Elena Rodriguez, Lourdes Hernández‐Cosido, Marta Leon, Paula Yong González, Teresa Durán, Tamara Parracho, Francisca Mulero, Rubén Nogueiras, J. Simon C. Arthur, Angel R. Nebreda, Roger J. Davis, Miguel Marcos, Guadalupe Sabio   +20 more
wiley   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

The role of aspirin in women’s health

, 2011
Freek WA Verheugt1, Antoinette C Bolte21Department of Cardiology, Onze Lieve Vrouwe Gasthuis (OLVG), Amsterdam, The Netherlands; 2VU University Medical Center, Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Amsterdam, The ...
Verheugt FWA, Bolte AC
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study

Caspian Journal of Internal Medicine, 2016
Background: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of ...
Emadouddin Moudi, Seyed-Reza Hosseini, Ali Bijani   +2 more
doaj  

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Bidirectional Disulfide Metathesis Enables Recycling of High‐Performance Thermoset Networks

Advanced Science, EarlyView.
A cyclic aromatic disulfide comonomer enables dual‐mode recyclable pDCPD thermosets through bidirectional disulfide metathesis. The resulting networks combine enhanced mechanical performance with thermal reprocessability and chemical depolymerization into reusable oligomeric fragments, allowing regeneration of high‐performance thermosets with minimal ...
Bohan Li, Jie Zheng, Daniel Paniroi Situmorang, Jia‐xin Neo, Hongzhi Feng, Jinling Li, Loh Xian‐Jun, Zibiao Li, Teck‐Peng Loh   +8 more
wiley   +1 more source