Results 151 to 160 of about 183,407 (264)

Aspirin Use for Secondary Prevention Amid Negative Messaging in Patients With Cardiovascular Disease.

JAMA Netw Open
Van't Hof JR, Duval S, Oldenburg N, Eder M, Luepker RV.   +4 more
europepmc   +1 more source

ABCD-GENE Score Stratifying Risk-Benefit Profile of Clopidogrel-Aspirin Therapy in Ischemic Stroke Within 24-72 Hours. [PDF]

J Stroke
Chen Y, Jiang L, Gao Y, Chen W, Yan H, Wang T, Yang Y, Pan Y, Wang Y.   +8 more
europepmc   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Body mass index adjusted aspirin dosing does not overcome pharmacokinetic and pharmacodynamic disadvantages in obese pregnant women at risk for preeclampsia: a prospective cohort study. [PDF]

Front Med (Lausanne)
Karaduman FS, Cim N, Caliskan M, Cim B, Ergani SY, Guleroglu FY, Cetin A.   +6 more
europepmc   +1 more source

Aspirin Poisoning [PDF]

BMJ, 1936
openaire   +2 more sources

Efficient Current‐Driven Perpendicular Magnetization Switching Through the Synergy of the Orbital and Spin Hall Effects

Advanced Science, EarlyView.
NiNb alloys enable efficient charge‐to‐spin conversion by combining the spin Hall effect of nickel with the orbital Hall effect of niobium. Composition tuning yields spin‐torque efficiencies of −1.4 to −1.7 and a non‐monotonic efficiency‐resistivity relationship, revealing orbital‐spin synergy beyond conventional spin Hall materials and offering a ...
Chuangwen Wu, Jing Zhou, Yibo Fan, Jiali Chen, Rongce Sun, Zonghao Deng, Zengxin Wei, Chuantong Ren, Xingen Zheng, Zhaowei Zhang, Jing Zhang, Jingfeng Li, Jinkui Zhao, Wei Jiang, Haibo Ke, Hao Wu, Weihua Wang   +16 more
wiley   +1 more source

Aspirin therapy after heart transplantation is associated with higher myocardial perfusion reserve assessed by cardiovascular magnetic resonance imaging. [PDF]

JHLT Open
Jablonowski R, Löfman IH, Andersson HB, Gjesdal G, Fogarasi C, Kellman P, Melin M, Engblom H, Arheden H, Carlsson M, Nickander J, Braun OÖ.   +11 more
europepmc   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Age-Related Platelet Cox-1 Upregulation in Atrial Fibrillation. [PDF]

Int J Mol Sci
Valeriani E, Cammisotto V, Menichelli D, Pastori D, Castellani V, Bartimoccia S, Cucchiara G, Pannunzio A, Palumbo IM, Martinelli O, Carnevale R, Violi F, Pignatelli P.   +12 more
europepmc   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source