Advances in Hematology, 2009 The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range
Khaled Mansour +3 more
doaj +9 more sources
Frequency of Aspirin Resistance in Ischemic Stroke Patients and Healthy Controls from Colombia [PDF]
Stroke Research and Treatment, 2021 Objective. To evaluate the aspirin resistance prevalence in patients with previous ischemic cerebrovascular disease undergoing aspirin therapy for secondary prevention. Materials and Methods.
Alejandro Roman-Gonzalez +12 more
doaj +2 more sources
Journal of Thrombosis and Haemostasis, 2005 Treatment failures occur with any drug and aspirin is no exception. Evidence is growing to indicate that there are subpopulations that do not respond to antithrombotic action of aspirin. The term 'aspirin resistance' has been used to describe a number of different phenomena, including inability of aspirin to: (i) protect against cardiovascular events ...
J Musiał, Anetta Undas, Marek Sanak
exaly +6 more sources
Long Non-Coding RNA H19 Positively Associates With Aspirin Resistance in the Patients of Cerebral Ischemic Stroke [PDF]
Frontiers in Pharmacology, 2020 Background and purposeAspirin is a novel anti-platelet drug that is intensively recommended for the prevention and treatment of cerebral ischemic stroke.
Jue Wang +8 more
doaj +2 more sources
Effect of aspirin resistance with dyslipidemia against VerifyNOW® measurement in Bethesda hospital Yogyakarta [PDF]
JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2015 Background: Aspirin is first line drug of choice to prevent ischemic stroke. However, some cases are found occuring of aspirin resistance. Objective: This study was to examine the effect of dyslipidemia on the risk of antiplatelet resistance with ...
Hardi astuti witasari +2 more
doaj +4 more sources
Influence of low‐dose aspirin, resistance exercise, and sex on human skeletal muscle PGE2/COX pathway activity [PDF]
Physiological Reports, 2021 Prostaglandin (PG) E2 has been linked to increased inflammation and attenuated resistance exercise adaptations in skeletal muscle. Nonaspirin cyclooxygenase (COX) inhibitors have been shown to reduce these effects.
Masatoshi Naruse +10 more
doaj +2 more sources
Epoxidase inhibitor-aspirin resistance and the relationship with genetic polymorphisms: a review [PDF]
Journal of International Medical ResearchStrokes are the leading cause of death in most regions of the world. Epoxidase inhibitors include the drug aspirin (acetylsalicylic acid). Aspirin is widely used as first-line treatment for the prevention of cardiovascular and cerebrovascular diseases in
Xiaolin Hou
doaj +2 more sources
Factors Associated with Aspirin Resistance in Hong Kong Chinese Patients with Stable Coronary Heart Disease Using the Multiplate® Analyzer and Serum Thromboxane B2 [PDF]
Pharmaceutics, 2022 Introduction: Aspirin resistance may be associated with various conditions. We measured serum thromboxane B2 (TXB2) and platelet function using the Multiplate® Analyzer with arachidonic acid (ASPI) in patients on long term aspirin therapy to identify ...
Weiwei Zeng +7 more
doaj +2 more sources
Platelet Function Assays for the Diagnosis of Aspirin Resistance
Platelets, 2022 Aspirin, an antiplatelet drug, is commonly used at low doses for numerous indications, including prophylaxis of cardiovascular, neurovascular, and venous thromboembolic events.
Nameer Van Oosterom +3 more
doaj +2 more sources
Low miR‐19b‐1‐5p Expression Is Related to Aspirin Resistance and Major Adverse Cardio‐ Cerebrovascular Events in Patients With Acute Coronary Syndrome [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Because of a nonresponse to aspirin (aspirin resistance), patients with acute coronary syndrome (ACS) are at increased risk of developing recurrent event.
Sandeep Singh +12 more
doaj +2 more sources