Results 21 to 30 of about 545 (197)

PENGARUH DIABETES MELLITUS TERHADAP RESISTENSI ASPIRIN PADA PASIEN STROKE ISKEMIK DI RUMAH SAKIT BETHESDA YOGYAKARTA

Pharmaciana, 2014
The secondary prevention of ischemic stroke can be implemented by giving aspirin. However, some cases of aspirin resistance have been found. The purpose of this study was to examine the influence of diabetes mellitus on the risk of aspirin resistance ...
Hardi Astuti Witasari, Rizaldy Taslim Pinzon, Erna Kristin   +2 more
doaj   +1 more source

Aspirin and clopidogrel resistance; a neglected gap in stroke and cardiovascular practice in Iran: a systematic review and meta-analysis

Thrombosis Journal, 2023
Objective Antiplatelet drugs, such as Aspirin and Clopidogrel (Plavix) are effective in the primary prevention of thromboembolic events. They are commonly used to reduce the risk of recurrence of thromboembolism.
Mohammad Parsa-kondelaji, Hassan Mansouritorghabeh   +1 more
doaj   +1 more source

Prevalence and Risk Factors for Aspirin Resistance in Elderly Patients With Type 2 Diabetes

International Journal of Gerontology, 2011
Background: Aspirin resistance in patients with diabetes is recognized. However, the prevalence and related risk factors for aspirin resistance in elderly patients with Type 2 diabetes have not been reported, which is why we undertook this study. Methods:
Lin Liu, Jian Cao, Li Fan, Guoliang Hu, Yixin Hu, Binpo Zhu, Xiaoli Li, Hao Wang, Jie Bai, Haiyan Shi   +9 more
doaj   +1 more source

Aspirin resistance: Prevalence and clinical outcome in Egypt

Egyptian Journal of Critical Care Medicine, 2015
Introduction: The antiplatelet drug aspirin is considered as a cornerstone in medical treatment of patients with CV or cerebrovascular diseases. Despite its use, a significant number of patients had recurrent adverse ischemic events.
Ahmed Salah, Mohammed El-Desuky, Amal Rizk, Amr El-Hadidy   +3 more
doaj   +1 more source

Low miR‐19b‐1‐5p Expression Is Related to Aspirin Resistance and Major Adverse Cardio‐ Cerebrovascular Events in Patients With Acute Coronary Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Because of a nonresponse to aspirin (aspirin resistance), patients with acute coronary syndrome (ACS) are at increased risk of developing recurrent event.
Sandeep Singh, Maurice W. J. de Ronde, Esther E. Creemers, Ingeborg Van der Made, Roelien Meijering, Mark Y. Chan, Sock Hwee Tan, Chee Tang Chin, A. Mark Richards, Richard W. Troughton, Alan Yean Yip Fong, Bryan P. Yan, Sara‐Joan Pinto‐Sietsma   +12 more
doaj   +1 more source

Non-compliance is the predominant cause of aspirin resistance in chronic coronary arterial disease patients

Journal of Translational Medicine, 2008
Background Our previous publication showed that 9% of patients with a history of myocardial infarction MI. could be labeled as aspirin resistant; all of these patients were aspirin resistant because of non-compliance.
Reeves Mathew, Barber Kimberly, Schwartz Dianne E, Schwartz Kenneth A, De Franco Anthony C   +4 more
doaj   +1 more source

CLINICAL SIGNIFICANCE OF ASPIRIN RESISTANCE IN PATIENTS WITH CARDIO-VASCULAR DISEASES

Рациональная фармакотерапия в кардиологии, 2016
Atherothrombosis is a complication of ischemic heart disease, and it leads to development of acute coronary syndrome. Atherothrombosis is characterized by sudden destruction of atherosclerotic plaque, which results into platelets activation and thrombus ...
P. J. Dovgalevsky, N. V. Furman, N. F. Puchinian   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Factors Associated with Aspirin Resistance in Hong Kong Chinese Patients with Stable Coronary Heart Disease Using the Multiplate^® Analyzer and Serum Thromboxane B₂

Pharmaceutics, 2022
Introduction: Aspirin resistance may be associated with various conditions. We measured serum thromboxane B2 (TXB2) and platelet function using the Multiplate® Analyzer with arachidonic acid (ASPI) in patients on long term aspirin therapy to identify ...
Weiwei Zeng, Tanya T. W. Chu, Elaine Y. K. Chow, Miao Hu, Benny S. P. Fok, Juliana C. N. Chan, Bryan P. Y. Yan, Brian Tomlinson   +7 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source