Results 41 to 50 of about 88,633 (281)

Aspirin resistance: Prevalence and clinical outcome in Egypt

Egyptian Journal of Critical Care Medicine, 2015
Introduction: The antiplatelet drug aspirin is considered as a cornerstone in medical treatment of patients with CV or cerebrovascular diseases. Despite its use, a significant number of patients had recurrent adverse ischemic events.
Ahmed Salah, Mohammed El-Desuky, Amal Rizk, Amr El-Hadidy   +3 more
doaj   +1 more source

Is there a role for oral triple therapy in patients with acute coronary syndromes without atrial fibrillation? [PDF]

, 2018
© 2018 Bentham Science PublishersBACKGROUND: Acute coronary syndrome (ACS) patients, despite treatment with dual antiplatelet therapy (DAPT), have up to 10% risk of recurrent major adverse cardiac events (MACE) in the short term.
Akhtar, Zaki, Farag, Mohamed, Gorog, Diana Adrienne, Spinthakis, Nikolaos   +3 more
core   +2 more sources

The Use of Prasugrel and Ticagrelor in Pipeline Flow Diversion [PDF]

, 2018
Background: Despite the routine clopidogrel/aspirin anti-platelet therapy, complications like thromboembolism, continue to be encountered with PED.
Atallah, MD, Elias, Bekelis, MD, Kimon, Chalouhi, MD, Nohra, Eller, MD, Gorge, Hasan, MD, David, Jabbour, Pascal, MD, Rosenwasser, MD, MBA, FACS, FAHA MD, Robert H., Saad, MD, Hassan, Stidd, MD, David, Tjoumakaris, MD, Stavropoula   +9 more
core   +2 more sources

Non-compliance is the predominant cause of aspirin resistance in chronic coronary arterial disease patients

Journal of Translational Medicine, 2008
Background Our previous publication showed that 9% of patients with a history of myocardial infarction MI. could be labeled as aspirin resistant; all of these patients were aspirin resistant because of non-compliance.
Reeves Mathew, Barber Kimberly, Schwartz Dianne E, Schwartz Kenneth A, De Franco Anthony C   +4 more
doaj   +1 more source

Sex-specific-differences in cardiovascular risk in type-1-diabetes : a cross sectional study [PDF]

, 2013
Background: Little is known about the impact of sex-specific differences in the management of type 1 diabetes (T1DM). Thus, we evaluated the influence of gender on risk factors, complications, clinical care and adherence in patients with T1DM.
Hinstersteiner, Juliane, Johnson, Julienne, Kamyar, Majid Reza, Kautzky, Alexander, Kautzky-Willer, Alexandra, Lemmens-Gruber, Rosa, Saukel, Johannes, Stich, Kathrin   +7 more
core   +1 more source

CLINICAL SIGNIFICANCE OF ASPIRIN RESISTANCE IN PATIENTS WITH CARDIO-VASCULAR DISEASES

Рациональная фармакотерапия в кардиологии, 2016
Atherothrombosis is a complication of ischemic heart disease, and it leads to development of acute coronary syndrome. Atherothrombosis is characterized by sudden destruction of atherosclerotic plaque, which results into platelets activation and thrombus ...
P. J. Dovgalevsky, N. V. Furman, N. F. Puchinian   +2 more
doaj   +1 more source

Biochemical aspirin resistance in stroke patients: a cross-sectional single centre study [PDF]

, 2013
Background: Aspirin use is known to reduce the recurrence of stroke. However, the clinical response to aspirin has been mixed. The rate of stroke recurrence whilst on aspirin treatment is still unacceptably high.
Ali, Raymond Azman, Basri, Hamidon, Md. Rani, Shahrul Azmin, Mohamed Ibrahim, Norlinah, Remli, Rabani, Sahathevan, Ramesh, Shah, Shamsul Azhar, Tan, Hui Jan, Wan Yahya, Wan Nur Nafisah   +8 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Prevention is better than cure, but...: Preventive medication as a risk to ordinariness? [PDF]

, 2011
Preventive health remains at the forefront of public health concerns; recent initiatives, such as the NHS health check, may lead to recommendations for medication in response to the identification of 'at risk' individuals. Little is known about lay views
Adams S., Backett K., Benson J., Blaxter M., Bosely S., Britten N., Brown S. R., Catherine M. Will, Charmaz K., Cornwell J., Crawford R., Davison C., Davison C., Davison C., Fowkes F. G.R., Greco M., Griffiths F., Hallowell N., Hansen D. L., Hansen D. L., Heald C., Helen C. Eborall, Lumme-Sandt K., Lumme-Sandt K., Lupton D., Mills C. W., Moen J., Murphy E., Nettleton S., Novas C., Nørreslet M., Pound P., Radley A., Rose N., Rothwell P. M., Sachs L., Strauss A., Weiner K., Will C.   +38 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source