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Polymorphism of Genetic Ambigrams [PDF]

open access: yesVirus Evolution, 2021
AbstractDouble synonyms in the genetic code can be used as a tool to test competing hypotheses regarding ambigrammatic narnavirus genomes. Applying the analysis to recent observations ofCulex narnavirus 1andZhejiang mosquito virus 3ambigrammatic viruses indicates that the open reading frame on the complementary strand of the segment coding for RNA ...
Gytis Dudas   +3 more
openaire   +3 more sources

Association of CNR1 and INSIG2 polymorphisms with antipsychotics-induced weight gain: a prospective nested case–control study

open access: yesScientific Reports, 2021
Weight gain is a frequent and severe adverse reaction in patients taking antipsychotics. The objective was to further investigate in a natural setting influential risk factors associated with clinically significant weight gain. An observational follow-up
Natalia Jimeno   +4 more
doaj   +1 more source

An insight into osteoarthritis susceptibility: Integration of immunological and genetic background

open access: yesBiomolecules & Biomedicine, 2021
Osteoarthritis (OA) is a progressive degenerative disease that affects all synovial joints, causing the disability of the main locomotor diarthrodial joints.
Debora Stefik   +6 more
doaj   +1 more source

Phosphodiesterase 8B Polymorphism rs4704397 Is Associated with Infertility in Subclinical Hypothyroid Females: A Case-Control Study [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2020
Background Subclinical hypothyroidism (SCH) remains largely unnoticed as a major cause of infertility due to asymptomatic. Polymorphisms of phosphodiesterase 8B gene (PDE8B) have been linked with various diseases, including female infertility.
Tabassum Mansuri   +4 more
doaj   +1 more source

Characterization of Streptococcus pneumoniae strains causing invasive infections using whole-genome sequencing

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2020
Purpose: antigenic and genetic characterization of Streptococcus pneumoniae strains isolated from patients with invasive forms of pneumococcal infection using whole-genome sequencing.Materials and Methods. The study was performed on 46 S.
Konstantin O. Mironov   +8 more
doaj   +1 more source

ALDH2 and ADH1 genetic polymorphisms may contribute to the risk of gastric cancer: a meta-analysis. [PDF]

open access: yesPLoS ONE, 2014
We conducted a meta-analysis of case-control studies to determine whether ALDH2, ADH1 and ADH2 genetic polymorphisms contribute to the pathogenesis of gastric cancer.The PubMed, CISCOM, CINAHL, Web of Science, Google Scholar, EBSCO, Cochrane Library, and
He-Ling Wang   +3 more
doaj   +1 more source

Association of the Neuropeptide Y LEU7PRO rs16139 and NEUREXIN 3 rs760288 Polymorphisms with Alcohol Dependence

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: Alcoholism is associated with genetic variants of genes related to alcohol metabolizing enzymes, dopaminergic, gamma-aminobutyric acidergic, glutamatergic, opioid, cholinergic, and serotonergic systems. Neurpeptide Y system and Neurexins were
Cem Sengul   +7 more
doaj   +1 more source

Personality traits of schizophrenic patients in remission and their first-degree relatives: a dopaminergic and glutamatergic gene polymorphism study

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: The dopaminergic and glutamatergic systems are of major interest in the etiology of schizophrenia and supposed endophenotypes such as personality traits.
Vesile Altinyazar, Azad Gunderici
doaj   +1 more source

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

open access: yes, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
McCarty, Catherine A.   +4 more
core   +1 more source

Genetic Polymorphisms within The Intronless ACTL7A and ACTL7B Genes Encoding Spermatogenesis-Specific Actin-Like Proteins in Japanese Males [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2019
Actins play essential roles in cellular morphogenesis. In mice, the T-actin1 and 2 genes, which encode actin-like proteins, are specifically expressed in haploid germ cells. Both T-ACTIN1/ACTLB and T-ACTIN2/ACTL7A have also been cloned and studied. The
Hiromitsu Tanaka   +3 more
doaj   +1 more source

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