Results 31 to 40 of about 21,877 (208)

Single nucleotide polymorphisms in asthma candidate genes TBXA2R, ADAM33 FCER1B and ORMDL3 in Pakistani asthmatics a case control study

open access: yesAsthma Research and Practice, 2018
Background Genetic variations in different loci and genes are important in asthma pathogenesis. There is much importance of various immunological pathways in the IgE secretion regulation.
Nusrat Saba   +7 more
doaj   +1 more source

Anti-Müllerian Hormone Gene Polymorphisms: Global Perspectives and Arab Population Insights

open access: yesDubai Medical Journal
Introduction: Anti-Müllerian Hormone (AMH) gene polymorphisms significantly impact ovarian function, follicular development, and fertility outcomes.
Huda Omran
doaj   +1 more source

Polymorphism of human haptoglobin and its clinical importance

open access: yesGenetics and Molecular Biology, 2008
Haptoglobin (Hp) is a plasma glycoprotein, the main biological function of which is to bind free hemoglobin (Hb) and prevent the loss of iron and subsequent kidney damage following intravascular hemolysis.
Vânia Peretti de Albuquerque Wobeto   +2 more
doaj   +1 more source

Association between insertion/deletion polymorphism of the ace gene with risk of hypertension

open access: yesGenetics & Applications, 2023
This study conducted an initial investigation into the association between ACE gene insertion/deletion (I/D) polymorphisms (rs1799752) and hypertension in the Republic of Srpska, Bosnia and Herzegovina.
Jovan Kulić   +6 more
doaj   +1 more source

Gene polymorphisms as markers of disease susceptibility [PDF]

open access: yesJournal of Medical Biochemistry, 2010
The most widespread diseases of modern man have a polygenic basis, including genetic predisposition and factors in the external environment. Such is the case with cardiovascular disease, malignancy, diabetes and so on.
Novaković Ivana   +3 more
doaj  

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean   +7 more
wiley   +1 more source

Emotional dimension associated with the migratory experience of adult refugees and asylum seekers

open access: yesScientific Reports
This study explores the impact of the migratory process on the mental health of refugees and asylum seekers arriving in Spain. It examines the feelings and emotions associated with emigration, alongside its underlying causes. A mixed-methods approach was
María José Cáceres-Titos   +2 more
doaj   +1 more source

Evaluation of multiple approaches to identify genome-wide polymorphisms in closely related genotypes of sweet cherry (Prunus avium L.)

open access: yesComputational and Structural Biotechnology Journal, 2017
Identification of genetic polymorphisms and subsequent development of molecular markers is important for marker assisted breeding of superior cultivars of economically important species.
Seanna Hewitt   +5 more
doaj   +1 more source

The quantitative genetics of phenotypic robustness. [PDF]

open access: yesPLoS ONE, 2010
Phenotypic robustness, or canalization, has been extensively investigated both experimentally and theoretically. However, it remains unknown to what extent robustness varies between individuals, and whether factors buffering environmental variation also ...
Hunter B Fraser, Eric E Schadt
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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