Results 21 to 30 of about 21,877 (208)
Role of Genetic Polymorphisms in Therapeutic Response to Anti-Asthma Therapy
Allergy, Asthma & Clinical Immunology, 2007 Over the past several decades, significant advances have been seen in the diagnosis and treatment of asthma. Recent research has focused on potential phenotypic and genotypic predictors of response to therapy. In this review, we will examine each of the
Oppenheimer John
doaj +1 more source
Why do Individuals Differ in Viral Susceptibility? A Story Told by Model Organisms
Viruses, 2017 Viral susceptibility and disease progression is determined by host genetic variation that underlies individual differences. Genetic polymorphisms that affect the phenotype upon infection have been well-studied for only a few viruses, such as HIV-1 and ...
Lisa van Sluijs +2 more
doaj +1 more source
Genetic Regulatory Networks of Apolipoproteins and Associated Medical Risks
Frontiers in Cardiovascular Medicine, 2022 Apolipoproteins (APO proteins) are the lipoprotein family proteins that play key roles in transporting lipoproteins all over the body. There are nearly more than twenty members reported in the APO protein family, among which the A, B, C, E, and L play ...
Preethi Basavaraju +6 more
doaj +1 more source
Genetic polymorphisms in lung disease: bandwagon or breakthrough?
Respiratory Research, 2002 The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define pathophysiology, to identify persons at risk for pulmonary disease and to predict ...
Rybicki Benjamin +2 more
doaj +1 more source
Genetic polymorphisms in sepsis
Pediatric Critical Care Medicine, 2005 Wide variability exists in the susceptibility to and outcome from sepsis even within similar intensive care unit populations. Some of this variability in the host may be due to genetic variation in genes coding for components of the innate immune response.To review the evidence for a genetic influence on the susceptibility to and outcome from sepsis ...
Mary K, Dahmer +3 more
openaire +3 more sources
Genetic modifiers of chromatin acetylation antagonize the reprogramming of epi-polymorphisms.
PLoS Genetics, 2012 Natural populations are known to differ not only in DNA but also in their chromatin-associated epigenetic marks. When such inter-individual epigenomic differences (or "epi-polymorphisms") are observed, their stability is usually not known: they may or ...
Anne-Laure Abraham +5 more
doaj +1 more source
Genetic polymorphisms in Afghanistan
Annals of Human Biology, 1977 The gene frequencies in samples of two language groups from Afghanistan, comprising 104 Pushtu and 179 Dari subjects living in Kabul, have been examined for 24 loci. Some systems suggest greater affinity to the west (e.g. the MS gene combination, the esterase D2 allele), some to the east (e.g.
S S, Papiha, D F, Roberts, A G, Rahimi
openaire +2 more sources
Genetic polymorphism and the link to stress-induced metabolic dysfunction
Babcock University Medical Journal, 2023 Background: The impact of stress on health is well-established and it continues to influence modern life. While some individuals may manage stress well, others may experience detrimental impacts on their physical and emotional health. As stress has been
Adekunle Mofolorunso +2 more
doaj +1 more source
Indian Journal of Dermatology, 2015 Background: Psoriasis is a chronic inflammatory disease driven by exaggerated production of pro-inflammatory cytokines and interleukins. Various genetic polymorphisms including IL-1 are implicated in pathogenesis of psoriasis. The exact role of IL-1 gene
Nikhil Moorchung +4 more
doaj +1 more source
Investigating the association between dental age and polymorphisms in genes encoding estrogen receptors [PDF]
Journal of Applied Oral Science, 2023 Background Genetic polymorphisms have been shown to influence several physiological traits, including dental and craniofacial characteristics. Understanding the clinical relevance of genetic polymorphisms in dental practice is crucial to personalize ...
Isabela Ribeiro MADALENA +9 more
doaj +1 more source