Results 41 to 50 of about 21,877 (208)
Novel Polymorphisms and Genetic Characteristics of the Prion Protein Gene in Pheasants
Frontiers in Veterinary Science, 2022 Transmissible spongiform encephalopathies (TSEs) also known as prion diseases, are fatal neurodegenerative diseases. Prion diseases are caused by abnormal prion protein (PrPSc) derived from normal prion protein (PrPC), which is encoded by the prion ...
Kyung Han Kim +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2020 Abstract Chapter 1 provides a brief introduction to genes and how they work for those without the necessary background or for review. Its emphasis is on the major types of genetic polymorphisms including single-nucleotide polymorphisms (SNPs), allele and genotype frequencies, and the utility of genetic polymorphisms in studying the ...
Dhafer A.F. Al-Koofee +1 more
openaire +3 more sources
Genetic polymorphisms as determinants of pesticide toxicity: Recent advances
Toxicology Reports, 2019 Occupational and environmental exposure to pesticides may induce harmful effects on human health by promoting the development of a wide range of disorders.
Michele Teodoro +3 more
doaj +1 more source
iScience, 2022 Summary: Neuronal oscillations, their inter-areal synchronization, and scale-free dynamics constitute fundamental mechanisms for cognition by regulating communication in neuronal networks.
Jaana Simola +7 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Genetic polymorphisms of αS1-, αS2- and k-casein in Maltese goat breed
Italian Journal of Animal Science, 2011 The casein genes are organized as a tight cluster including αS1- (CSN1S1), β- (CSN2), αS2- (CSN1S2) and k-casein (CSN3). Investigation at casein haplotype level is therefore necessary to detect effects which could be used for the genetic
A. Caroli +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
ASPIRIN RESISTANCE CANDIDATE GENES AND THEIR ASSOCIATION WITH THE RISK OF CARDIOVASCULAR EVENTS
Кардиоваскулярная терапия и профилактика, 2013 The review presents the current literature evidence on the most likely genetic polymorphisms of aspirin resistance, such as polymorphisms of cyclooxygenase, glycoproteins GP Ib/IIIa, GP Ibα, GP VI, and adenosine diphosphate receptors P2Y1 and P2Y12.
Yu. I. Grinshtein +2 more
doaj +1 more source
Brazilian Journal of Anesthesiology, 2022 Background: The genetic polymorphisms of the alpha-2A adrenergic receptor (ADRA2A), which plays a significant role in sedation, anxiety relief, and antinociception, particularly in dexmedetomidine, may differ in the degree of sedation.
Yoon Ji Choi +4 more
doaj +1 more source