Results 11 to 20 of about 2,522,601 (297)

Effect of genetic polymorphisms on Alzheimer’s disease treatment outcomes: an update

open access: yesClinical Interventions in Aging, 2019
Riyadi Sumirtanurdin,1 Amirah Y Thalib,1 Kelvin Cantona,1 Rizky Abdulah1,2 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, Indonesia; 2Center of Excellence in Higher Education for ...
Sumirtanurdin R   +3 more
doaj   +1 more source

Polymorphism of Genetic Ambigrams [PDF]

open access: yesVirus Evolution, 2021
Abstract Double synonyms in the genetic code can be used as a tool to test competing hypotheses regarding ambigrammatic narnavirus genomes. Applying the analysis to recent observations of Culex narnavirus 1 and Zhejiang mosquito virus 3 ...
Gytis Dudas   +3 more
openaire   +4 more sources

Common Genetic Variation and the Control of HIV-1 in Humans [PDF]

open access: yes, 2009
To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects.
Cirulli, Elizabeth T   +319 more
core   +2 more sources

A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme [PDF]

open access: yes, 2012
Background: Low muscle mass and function have been associated with poorer indicators of physical capability in olderpeople, which are in-turn associated with increased mortality rates.
Kumari, Meena   +99 more
core   +1 more source

Common NFKBIL2 polymorphisms and susceptibility to pneumococcal disease: a genetic association study. [PDF]

open access: yes, 2010
INTRODUCTION: Streptococcus pneumoniae remains a major global health problem and a leading cause of death in children worldwide. The factors that influence development of pneumococcal sepsis remain poorly understood, although increasing evidence points ...
Rautanen, Anna   +59 more
core   +1 more source

Why do Individuals Differ in Viral Susceptibility? A Story Told by Model Organisms

open access: yesViruses, 2017
Viral susceptibility and disease progression is determined by host genetic variation that underlies individual differences. Genetic polymorphisms that affect the phenotype upon infection have been well-studied for only a few viruses, such as HIV-1 and ...
Lisa van Sluijs   +2 more
doaj   +1 more source

Association between TAS2R38 gene polymorphisms and colorectal cancer risk [PDF]

open access: yes, 2011
Molecular sensing in the lingual mucosa and in the gastro-intestinal tract play a role in the detection of ingested harmful drugs and toxins. Therefore, genetic polymorphisms affecting the capability of initiating these responses may be critical for the ...
Stemmler, Susanne   +23 more
core   +1 more source

Investigation of host candidate malaria-associated risk/protective SNPs in a Brazilian Amazonian population. [PDF]

open access: yes, 2012
The Brazilian Amazon is a hypo-endemic malaria region with nearly 300,000 cases each year. A variety of genetic polymorphisms, particularly in erythrocyte receptors and immune response related genes, have been described to be associated with ...
Rockett, Kirk A.   +31 more
core   +1 more source

Genetic Regulatory Networks of Apolipoproteins and Associated Medical Risks

open access: yesFrontiers in Cardiovascular Medicine, 2022
Apolipoproteins (APO proteins) are the lipoprotein family proteins that play key roles in transporting lipoproteins all over the body. There are nearly more than twenty members reported in the APO protein family, among which the A, B, C, E, and L play ...
Preethi Basavaraju   +6 more
doaj   +1 more source

CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development [PDF]

open access: yes, 2016
Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe forms of asthma. It has never been addressed whether SNPs in CHI3L1 and cord blood YKL-40 levels
Gorlanova, Olga   +23 more
core   +2 more sources

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