Results 11 to 20 of about 88,633 (281)
Factors associated with aspirin resistance in diabetic patients: A metabolic and inflammatory profile analysis. [PDF]
PLoS ONEBackgroundDiabetes mellitus (DM) is strongly linked to both first-time and recurrent atherosclerotic thrombotic events. Although aspirin (ASA) is commonly used to prevent cardiovascular diseases, studies have shown that ASA does not significantly reduce ...
Bo Chen +5 more
doaj +2 more sources
The association between aspirin resistance and extent and severity of coronary atherosclerosis [PDF]
İstanbul Kuzey Klinikleri, 2018 INTRODUCTION[|]Uncontrolled inflammatory responses could contribute to the pathogenesis of many leading causes of human morbidity and mortality. Aspirin is an anti-inflammatory and antithrombotic drug that is used in the primary and secondary protection ...
Serkan Kahraman +5 more
doaj +2 more sources
British Journal of Surgery, 2002 OBJECTIVE: To review the literature addressing the problem of aspirin resistance in patients with vascular disease. DATA SOURCES: A MEDLINE search (1966–February 2002) was performed. Key search terms included aspirin, resistance, resistant, failure, tolerance, and nonresponder.
J, Smout, G, Stansby
+7 more sources
The prevalence and associated factors of aspirin resistance among prophylactic aspirin users [PDF]
Romanian Journal of Neurology, 2021 Background. Aspirin is an antiplatelet used for the secondary prevention after vascular events. It is also suggested for the primary prevention of vascular events in high risk people, however, despite using standard prophylactic doses, aspirin resistance
Samaneh Ghorbani-Shirkouhi +5 more
doaj +1 more source
Aspirin and Clopidogrel Resistance [PDF]
Mayo Clinic Proceedings, 2006 Despite aspirin's and clopidogrel's proven benefit in reducing cardiovascular (CV) events, recurrent CV events still occur in patients receiving antiplatelet therapy. Many of these patients are resistant or only partially responsive to the antiplatelet effects of aspirin and clopidogrel, as determined by standard platelet assays.
Erin D, Michos +4 more
openaire +2 more sources
Low dose aspirin and pregnancy: how important is aspirin resistance? [PDF]
BJOG: an International Journal of Obstetrics and Gynaecology, 2016 Kate Navaratnam, Zarko Alfirevic
exaly +2 more sources
In Silico screening of nonsteroidal anti-inflammatory drugs and their combined action on Prostaglandin H Synthase-1 [PDF]
, 2010 The detailed kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was applied to in silico screening of dose-dependencies for the different types of nonsteroidal anti-inflammatory drugs (NSAIDs), such as: reversible/irreversible, nonselective/selective ...
Demin, Oleg +5 more
core +5 more sources
Aspirin resistance in patients with acute coronary syndrome. Part 2
Кардиоваскулярная терапия и профилактика, 2011 Aim. In patients with acute coronary syndrome (ACS), to investigate the prevalence of aspirin resistance, its clinical features, prognostic effects, and potential correction. Material and methods.
N. S. Frolova +4 more
doaj +1 more source
Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. [PDF]
, 2006 BACKGROUND AND PURPOSE: Aspirin resistance may be relatively common and associated with adverse outcome. Meta-analysis has clearly shown that 75 mg plain aspirin is the lowest effective dose; however, it is not known whether the recent increased use of ...
Byrne, Michael F +5 more
core +1 more source
Herz Kardiovaskuläre Erkrankungen, 2008 Recent clinical studies have shown that the expected antiplatelet effect of aspirin is not always achieved. From the laboratory point of view, resistance to aspirin is the inability to achieve the expected inhibition of platelet cyclooxygenase-(COX-)1 with prevention of platelet thromboxane (TX) A2 formation.
Norbert, Zimmermann +2 more
+7 more sources