Results 11 to 20 of about 545 (197)

Decreased turnover aspirin resistance by bidaily aspirin intake and efficient cytoreduction in myeloproliferative neoplasms

Platelets, 2018
Essential thrombocythemia (ET) and polycythemia vera (PV) are myeloproliferative neoplasms (MPN) with an increased risk of arterial and venous thrombosis.
Andréas Perrier-Cornet, Jean-Christophe Ianotto, Fanny Mingant, Maëla Perrot, Eric Lippert, Hubert Galinat   +5 more
doaj   +1 more source

Mechanistic view into the therapeutic effect, anticancer potential and the adverse effect of aspirin [PDF]

MATEC Web of Conferences
In this research, the working mechanism behind the therapeutic effect of aspirin will be discussed in detail. Aspirin will also be assessed as a promising drug to treat cancerous cells in the future.
Ouyang Juan
doaj   +1 more source

TRUE RESISTANCE AND PSEUDORESISTANCE TO ASPIRIN

Рациональная фармакотерапия в кардиологии, 2015
Low dose aspirin reduces the secondary incidence of myocardial infarction and stroke. Drug resistance to aspirin might result in treatment failure.
A. I. Martynov, E. V. Akatova, I. V. Urlayeva, O. P. Nicolin   +3 more
doaj   +3 more sources

Platelet Function Assays for the Diagnosis of Aspirin Resistance

Platelets, 2022
Aspirin, an antiplatelet drug, is commonly used at low doses for numerous indications, including prophylaxis of cardiovascular, neurovascular, and venous thromboembolic events.
Nameer Van Oosterom, Michael Barras, Neil Cottrell, Robert Bird   +3 more
doaj   +1 more source

'Aspirin resistance' or treatment non-compliance: Which is to blame for cardiovascular complications?

Journal of Translational Medicine, 2008
Aspirin is one of the 'cornerstone' drugs in our current management of cardiovascular disorders. However, despite the prescription of aspirin recurrent vascular events still occur in 10–20% of patients.
Shantsila Eduard, Lip Gregory YH
doaj   +1 more source

Aspirin resistance and ischemic heart disease on Iranian experience

Advanced Biomedical Research, 2012
Background: Coronary artery disease (CAD) and myocardial infarction are the most common causes of mortality and morbidity all over the world.
Masoumeh Sadeghi, Afsoon Emami, Naghmeh Ziyaei, Majid Yaran, Allahyar Golabchi, Azam Sadeghi   +5 more
doaj   +1 more source

Aspirin resistance in patients with ischemic stroke

Southern Clinics of Istanbul Eurasia, 2019
INTRODUCTION[|]Aspirin is the basic agent of antithrombotic treatment in ischemic cerebrovascular disease (CVD) patients. However several patients don't respond to treatment and therefore aspirin resistance term has been used lately.
Anıl Bulut, Sultan Çağırıcı, Vildan Yayla, Murat Çabalar, Songül Şenadım   +4 more
doaj   +1 more source

The association of four common polymorphisms from four candidate genes (COX-1, COX-2, ITGA2B, ITGA2) with aspirin insensitivity: a meta-analysis. [PDF]

PLoS ONE, 2013
OBJECTIVE: Evidence is mounting suggesting that a strong genetic component underlies aspirin insensitivity. To generate more information, we aimed to evaluate the association of four common polymorphisms (rs3842787, rs20417, rs201184269, rs1126643) from ...
Zhiyuan Weng, Xiaobo Li, Yuqiong Li, Jinxiu Lin, Feng Peng, Wenquan Niu   +5 more
doaj   +1 more source

Aspirin resistance: causes, clinical significance, correction

Mìžnarodnij Endokrinologìčnij Žurnal, 2022
Aspirin is the most frequently prescribed antiplatelet agent today. It exerts its antiplatelet effect by irreversible inactivation of the platelet cyclooxygenase-1, resulting in an irreversible inhibition of thromboxane-A2 formation. The clinical benefit
G.F. Gendeleka, A.N. Gendeleka
doaj   +1 more source

Influence of low‐dose aspirin, resistance exercise, and sex on human skeletal muscle PGE2/COX pathway activity

Physiological Reports, 2021
Prostaglandin (PG) E2 has been linked to increased inflammation and attenuated resistance exercise adaptations in skeletal muscle. Nonaspirin cyclooxygenase (COX) inhibitors have been shown to reduce these effects.
Masatoshi Naruse, William A. Fountain, Alex Claiborne, Toby L. Chambers, Andrew M. Jones, Andrew M. Stroh, Cristhian F. Montenegro, Colleen E. Lynch, Kiril Minchev, Scott Trappe, Todd A. Trappe   +10 more
doaj   +1 more source