Results 191 to 200 of about 359,713 (306)

Combining Spatial Multi‐Omics Data to Decipher Spatial Domains and Elucidate Cell Heterogeneity Based on Self‐Supervised Graph Learning

Advanced Science, EarlyView.
A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu, Rui Qiao, Ying Li, Junhong Li, Nuoya Yue, Jing Ge, Jiao Wang, Luonan Chen, Peiluan Li   +8 more
wiley   +1 more source

Long-term single antiplatelet therapy for patients with acute coronary syndrome at high-risk for ischemia and bleeding: a precision cohort study. [PDF]

Front Cardiovasc Med
Wanda M, Mengjie L, Jingyao W, Xue S, Xiao W, Cairong L, Yachao L, Zhigang Z, Zengming X.   +8 more
europepmc   +1 more source

Versatile DNA‐Functionalized Biohybrid Hydrogel Platforms for Electrothermally Activated On‐Demand Payload Release

Advanced Science, EarlyView.
A DNA‐functionalized biohybrid hydrogel is developed by integrating Cu‐mediated nucleic acid microflowers into a thermoresponsive matrix, enabling electrothermally triggered, on‐demand payload release. The platform offers spatiotemporally controllable therapeutic delivery with promising applications in precision oncology, neural regulation, and chronic
Mengqiu Sun, Zhenshuai Tang, Jia Zhang, Rui Song, Wei Luo, Juan Huang, Jincheng Zeng, Zhen He, Hao Zhang   +8 more
wiley   +1 more source

Aspirin alters molecular crosstalk between prostaglandin, apoptosis, and invasion pathways in colorectal cancer. [PDF]

BMC Cancer
Mostafavi-Fini HS, Moradi A, Gowdini E, Mohammadi R, Abdollahi T, Jamshidian F, Ganji SM.   +6 more
europepmc   +1 more source

Heterojunction‐Engineered Mass Spectrometry Platform for Deciphering Serum Metabolic Fingerprints in Diagnosis of Respiratory Diseases

Advanced Science, EarlyView.
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen, Chaoqi Wang, Xi Yu, Yuming Jiang, Yijiao Qu, Huihui Fu, Yuyin Bu, Xiaoyong Zhang, Zongxiu Nie   +8 more
wiley   +1 more source

Modifiable Correlates With Systemic Thromboxane Generation and Association With Cardiovascular Outcomes: Results From the Framingham Heart Study. [PDF]

Arterioscler Thromb Vasc Biol
Qian F, Gajjar P, Prescott B, Mitchell GF, Xanthakis V, Rade JJ, Nayor M.   +6 more
europepmc   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan, Hongmei Yang, Renfei Wu, Meng Hao, Xiangpeng Chu, Chuxia Deng, Kathy Qian Luo   +6 more
wiley   +1 more source

CO2‐Assisted Hydrolysis of NaBH4: A Multi‐Function Platform for Enhanced Hydrogen Release, Regeneration of NaBH4, and CO2‐to‐CH4 Conversion

Advanced Science, EarlyView.
CO2 significantly accelerates hydrogen release from aqueous NaBH4 without metal catalysts, eliminating the need for downstream separation. Ball‐milling the hydrolytic products with Mg regenerates NaBH4 with yields exceeding 76% while simultaneously producing methane.
Rui Han, Stella Zhang, Yan Dai, Michael Scott, Brandon He, Sadegh Shabani, Oliver Hutt, Matthew David, Zhenguo Huang   +8 more
wiley   +1 more source

Safety and efficacy of flow diversion for blood blister aneurysms: A comprehensive systematic review and meta-analysis. [PDF]

Neurosurg Rev
Maroufi SF, Fallahi MS, Thomas AJ, Tonetti DA.   +3 more
europepmc   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source